Abstract: Apparatus and methods according to various aspects of the present technology may comprise a treatment device configured for localized application of temperature treatment to aid in the therapeutic treatment of hemorrhoid disease. In one embodiment, the treatment device may comprise a body suitably configured to be placed directly against an external portion of an intergluteal space proximate to an anal verge of a user to allow localized exchange of heat energy between the external portion of the intergluteal space and composition disposed within a cavity of the body. In one embodiment, the body may be configured to be retained in position against the treatment area during use and to decrease a possibility of being inadvertently displaced after being positioned for use.