Patents by Inventor Lisa Lindesmith

Lisa Lindesmith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • STABILIZED NOROVIRUS VIRUS-LIKE PARTICLES AS VACCINE IMMUNOGENS
    Publication number: 20230381293
    Abstract: Recombinant Norovirus Virus-Like Particles (VLPs) formed from recombinant Norovirus VP1 proteins, and methods of their use and production are disclosed. In several embodiments, the Recombinant Norovirus VLPs can be used to generate an immune response to Norovirus VP1 protein in a subject. In additional embodiments, an effective amount of the recombinant Norovirus VLPs can be administered to a subject in a method of inhibiting a Norovirus infection.
    Type: Application
    Filed: October 14, 2021
    Publication date: November 30, 2023
    Applicants: The United States of America, as represented by the Secretary, Department of Health and Human Servic, The University of North Carolina at Chapel Hill, Board of Regents, the University of Texas System
    Inventors: Peter Kwong, Raffaello Verardi, Yaroslav Tsybovsky, Jason Gorman, Gwo-Yu Chuang, Li Ou, Lisa Lindesmith, Ralph Baric, George Georgiou, Inga Rimkute, Mario Roederer
  • Multivalent Immunogenic Compositions Against Noroviruses and Methods of Use
    Publication number: 20110070260
    Abstract: The invention provides immunogenic formulations comprising virus-like particles (VLPs) from two or more genoclusters and/or strains of norovirus in a pharmaceutically acceptable carrier. In representative embodiments, the formulation also comprises an adjuvant, for example, a viral adjuvant or CpG. The invention also provides methods of inducing an immune response to one or more noroviruses.
    Type: Application
    Filed: September 3, 2010
    Publication date: March 24, 2011
    Inventors: Ralph S. Baric, Anna LoBue, Robert Edward Johnston, Joseph Thompson, Lisa Lindesmith