Patents by Inventor Lisa Marie Thomasco

Lisa Marie Thomasco has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 8420646
    Abstract: The present invention is directed to tricyclic tetrahydroquinoline compounds of formula I, and pharmaceutically acceptable salts thereof wherein the variables R1, R2, R3, R4, R5, R20 and X are as described herein and to pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Grant
    Filed: December 20, 2010
    Date of Patent: April 16, 2013
    Assignee: PAH P&U LLC
    Inventors: Michael Robert Barbachyn, Paul Joseph Dobrowolski, Alexander Ross Hurd, Dennis Joseph McNamara, John Raymond Palmer, Arthur Glenn Romero, J. Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood
  • Tricyclic Tetrahydroquinoline Antibacterial Agents
    Publication number: 20110092494
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: December 20, 2010
    Publication date: April 21, 2011
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • TRICYCLIC TETRAHYDROQUINOLINE ANTIBACTERIAL AGENTS
    Publication number: 20100022524
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: August 28, 2009
    Publication date: January 28, 2010
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 7605157
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I and pharmaceutical compositions thereof, that exhibit useful antibacterial activity again a wide range of human and veterinary pathogens
    Type: Grant
    Filed: March 7, 2007
    Date of Patent: October 20, 2009
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Acyloxymethylcarbamate prodrugs of oxazolidinones
    Patent number: 7265140
    Abstract: The present invention relates to acyloxymethylcarbamate oxazolidinones. The compounds of the present invention have potent activity with excellent oral bioavailability against Gram-positive and Gram-negative bacteria.
    Type: Grant
    Filed: September 9, 2004
    Date of Patent: September 4, 2007
    Assignee: Pfizer Inc
    Inventors: Vara Prasad Venkata Nagendra Josyula, Robert C. Gadwood, Lisa Marie Thomasco, Ji-Young Kim, Allison Laura Choy, Frederick Earl Boyer
  • Tricyclic tetrahydroquinoline antibacterial agents
    Patent number: 7208490
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens
    Type: Grant
    Filed: October 2, 2003
    Date of Patent: April 24, 2007
    Assignee: Pharmacia & Upjohn Company LLC
    Inventors: Michael Robert Barbachyn, Gordan L. Bundy, Paul Joseph Dobrowolski, Alexander Ross Hurd, Gary E. Martin, Dennis Joseph McNamara, John Raymond Palmer, Donna L. Romero, Arthur Glenn Romero, J. Craig Ruble, Debra Ann Sherry, Lisa Marie Thomasco, Peter Laurence Toogood
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Patent number: 6972286
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Grant
    Filed: November 14, 2001
    Date of Patent: December 6, 2005
    Assignee: Pharmacia and Upjohn Company
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Oxazolidinone photoaffinity probes
    Patent number: 6875871
    Abstract: Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: April 5, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Lisa Marie Thomasco, Robert C. Gadwood
  • Oxazolidinone photoaffinity probes
    Patent number: 6861433
    Abstract: The present invention provides compounds of the formula: compositions comprising such compounds, and methods for using the same.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: March 1, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Lisa Marie Thomasco, Robert C. Gadwood
  • Oxazolidinone photoaffinity probes
    Patent number: 6858635
    Abstract: Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.
    Type: Grant
    Filed: February 6, 2003
    Date of Patent: February 22, 2005
    Assignee: Pharmacia & Upjohn Company
    Inventors: Lisa Marie Thomasco, Robert C. Gadwood
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Publication number: 20040186293
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Application
    Filed: March 19, 2004
    Publication date: September 23, 2004
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Publication number: 20040176609
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Application
    Filed: March 19, 2004
    Publication date: September 9, 2004
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Tricyclic tetrahydroquinoline antibacterial agents
    Publication number: 20040162279
    Abstract: The invention includes tetrahydroquinoline and related compounds of formula I, and pharmaceutical compositions thereof, that exhibit useful antibacterial activity against a wide range of human and veterinary pathogens.
    Type: Application
    Filed: October 2, 2003
    Publication date: August 19, 2004
    Inventors: Michael Robert Barbachyn, J. Craig Ruble, Arthur Glenn Romero, Lisa Marie Thomasco, Alexander Ross Hurd, John Raymond Palmer, Peter Laurence Toogood, Dennis Joseph McNamara, Debra Ann Sherry, Paul Joseph Dobrowolski
  • Oxazolidinone photoaffinity probes
    Publication number: 20030232008
    Abstract: Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.
    Type: Application
    Filed: February 6, 2003
    Publication date: December 18, 2003
    Inventors: Lisa Marie Thomasco, Robert C. Gadwood
  • Oxazolidinone photoaffinity probes
    Publication number: 20030232840
    Abstract: Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.
    Type: Application
    Filed: February 6, 2003
    Publication date: December 18, 2003
    Inventors: Lisa Marie Thomasco, Robert C. Gadwood
  • Oxazolidinone photoaffinity probes
    Publication number: 20030073696
    Abstract: Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.
    Type: Application
    Filed: December 15, 2000
    Publication date: April 17, 2003
    Inventors: Lisa Marie Thomasco, Robert C. Gadwood
  • Oxazolidinones having a benzannulated 6- or 7-membered heterocycle
    Publication number: 20020133021
    Abstract: The present invention provides oxazolidinones having a benzannelated 6- or 7-membered heterocycle as antibacterial agents.
    Type: Application
    Filed: November 14, 2001
    Publication date: September 19, 2002
    Inventors: Paul D. Johnson, Paul Adrian Aristoff, Toni-Jo Poel, Lisa Marie Thomasco
  • Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agents
    Patent number: 5977373
    Abstract: The present invention provides thiadiazolyl and oxadiazolyl phenyl oxzolidinone compounds of formula I ##STR1## wherein Q is thiadiazolyl or oxadiazolyl; wherein X.sup.1 and X.sup.2 are independently hydrogen, fluorine or chlorine; andwherein R.sup.1 is, for example, --COCH.sub.3 or --COCH.sub.2 CH.sub.3.These compounds are useful antimicrobial agents, effective against a number of human and veterinary pathogens, including gram-positive and gram-negative aerobic bacteria.
    Type: Grant
    Filed: July 8, 1998
    Date of Patent: November 2, 1999
    Assignee: Pharmacia & Upjohn Company
    Inventors: Robert C. Gadwood, Lisa Marie Thomasco, David John Anderson