Patents by Inventor Lisa Michels

Lisa Michels has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROBABILISTIC IDENTIFICATION OF FEATURES FOR MACHINE LEARNING ENABLED CELLULAR PHENOTYPING
    Publication number: 20250259700
    Abstract: A method may include extracting a plurality of features for each cell depicted in an image. A biomarker identification model may be applied to determine, based on the features associated with each cell, whether the cell is associated with various biomarkers. A set of probabilities for each cell in the population of cells may be determined based on an output of the biomarker identification model. The set of probabilities may include, for each biomarker, a probability of a corresponding cell being associated with the biomarker. One or more subsets of cells, each of which corresponding to a different cellular phenotype, may be identified based on the set of probabilities associated with each cell. A feature set associated with each subset of cells may be identified as being indicative of a probability of a cell being associated with a corresponding phenotype. Related systems and computer program products are also provided.
    Type: Application
    Filed: May 1, 2025
    Publication date: August 14, 2025
    Inventors: Lisa Michelle MCGINNIS, Tatiana NOVITSKAYA, Andries ZIJLSTRA
  • SIMULTANEOUS IMAGING OF NUCLEIC ACID AND PROTEIN IN A SAMPLE
    Publication number: 20250250622
    Abstract: The present disclosure relates to the simultaneous imaging of nucleic acids and proteins in a sample. In particular, the present disclosure provides compositions, methods, systems and kits for imaging at least one target protein and at least one target nucleic acid in a single sample.
    Type: Application
    Filed: April 24, 2025
    Publication date: August 7, 2025
    Applicant: GENENTECH, INC.
    Inventors: Eric Scott LUBECK, Lisa Michelle MCGINNIS, Reuben MONCADA, Orit ROZENBLATT-ROSEN
  • Compositions and methods of a dihydroisoxazole compound that reduces ectoparasite infestations on fish
    Patent number: 12280040
    Abstract: Ectoparasite infestations in fish farming can pose significant challenges and issues for aquaculture operations. This disclosure generally relates to treatment or control of ectoparasite infestations (such as sea lice infestations) on fish (such as salmonids) using a particular dosing regimen of an isoxazoline. In particular, the dosing regimen includes oral administration of the active ingredient: (S)-3-methyl-N-(2-oxo-2-(prop-2-yn-1-ylamino) ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl) thiophene-2-carboxamide, including salts, or N-oxide, or solvates thereof, of structural formula The active ingredient may be administered at a dosage (i.e., in a dose) of from about 0.025 mg/kg/d to about 0.250 mg/kg/d. The dosing regimen may include oral administration from about 3 to about 10 consecutive days.
    Type: Grant
    Filed: September 13, 2024
    Date of Patent: April 22, 2025
    Assignee: EVAH Atlantic Inc.
    Inventor: Lisa Michele Phillips
  • DIHYDROISOXAZOLE COMPOUND FOR USE IN REDUCING ECTOPARASITE INFESTATIONS ON FISH
    Publication number: 20250090503
    Abstract: Ectoparasite infestations in fish farming can pose significant challenges and issues for aquaculture operations. This disclosure generally relates to treatment or control of ectoparasite infestations (such as sea lice infestations) on fish (such as salmonids) using a particular dosing regimen of an isoxazoline. In particular, the dosing regimen includes oral administration of the active ingredient: (S)-3-methyl-N-(2-oxo-2-(prop-2-yn-1-ylamino)ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)thiophene-2-carboxamide, including salts, or N-oxide, or solvates thereof, of structural formula at a dosage (i.e., in a dose) of from about 0.025 mg/kg/d to about 0.250 mg/kg/d, preferably at a dosage of from about 0.025 mg/kg/d to about 0.125 mg/kg/d. In particular, the dosing regimen includes oral administration from about 3 to about 10 consecutive days, preferably during 7 consecutive days.
    Type: Application
    Filed: September 13, 2024
    Publication date: March 20, 2025
    Inventor: Lisa Michele PHILLIPS
  • Optoacoustic probe
    Patent number: 12186099
    Abstract: An optoacoustic probe for optoacoustic imaging of a volume, the optoacoustic probe having a distal end operable to contact the volume and a proximal end. The optoacoustic probe includes at least one primary light source and an auxiliary light source that is configured to generate auxiliary light carried through an optical window to a volume. A detection device is configured to detect signals generated from the auxiliary light or primary light reflecting from the volume or the optical window. A microcontroller including one or more processors is also provided, that receives the signals generated from the auxiliary light reflecting from the volume from the detection device, determines contact between the volume and the optoacoustic probe based on the auxiliary light reflecting from the volume, and prevents the at least one primary light source from generating light until the optoacoustic probe is contacting the volume.
    Type: Grant
    Filed: May 3, 2022
    Date of Patent: January 7, 2025
    Assignee: SENO MEDICAL INSTRUMENTS, INC.
    Inventors: Jeffrey Nelson Harris, Tam Thien Do, Xavier Rey Saenz, Lisa Michelle Richards Cook
  • Training Pipeline for Training Machine-Learned User Interface Customization Models
    Publication number: 20250004797
    Abstract: Example embodiments of the present disclosure provide for an example method. The example method includes obtaining session data descriptive of a plurality of user sessions, the plurality of user sessions respectively including an interaction with an input element rendered at a user device and a request for a resource associated with the input element. The example method includes obtaining, using a first machine-learned model, a plurality of weights associated with the plurality of user sessions by, for a respective user session of the plurality of user sessions: inputting, to the first machine-learned model, data descriptive of one or more characteristics of the respective user session; and obtaining, from the first machine-learned model, a respective weight of the plurality of weights, the respective weight indicative of an incremental probability of the request conditioned on rendering of the input element.
    Type: Application
    Filed: June 14, 2023
    Publication date: January 2, 2025
    Inventors: Lisa Michelle Jakobovits, Jonathan James Mulligan, Mert Dikmen, Xinlong Bao, John Chen, Jing Wang
  • METHODS, PRODUCTS AND SYSTEMS FOR PROGNOSIS OF SUBJECTS SUFFERING FROM MULTIPLE MYELOMA
    Publication number: 20240110915
    Abstract: The present disclosure relates to methods, products and systems for the prognosis of subjects suffering from multiple myeloma. In certain embodiments, the present disclosure provides a method of prognosis for a subject suffering from multiple myeloma. The method comprises determining the level of desmoglein 2 (DSG2) in malignant plasma cells from the subject, wherein an increased level of DSG2 in the plasma cells is indicative of a poorer prognosis for the subject.
    Type: Application
    Filed: November 16, 2021
    Publication date: April 4, 2024
    Applicants: University of South Australia, Central Adelaide Local Health Inc, The University of Adelaide
    Inventors: Craig Thomas Wallington-Beddoe, Claudine Sharon Bonder, Lisa Michelle Ebert
  • Consolidated data restoration framework
    Patent number: 11822435
    Abstract: Embodiments of the present invention provide a system for identifying occurrence of events and performing one or more actions to mitigate the impacts of the events. The system is configured for gathering data from one or more data sources of an entity, generating dataflows using the data gathered from the one or more data sources, identifying an anomaly based on one or more indicators and the dataflows, determining occurrence of an event and generating one or more propagation models associated with the event, performing event impact analysis based on the one or more propagation models, perform one or more actions to contain the event based on the one or more propagation models, identifying a last good copy of data based on the data gathered from the one or more data sources, retrieving the last good copy of data, and restoring the last good copy of data.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: November 21, 2023
    Assignee: BANK OF AMERICA CORPORATION
    Inventors: Christopher Emmanuel Huntley, Musa Ajakaiye, Prasad V. Annadata, Dnyanesh P. Ballikar, Sina Bauer, Jason Kenneth Bellew, Timothy John Bendel, David Alan Beumer, Michelle Andrea Boston, Lisa Julia Brown, Robin J. Buck, Brian C. Busch, Salvatore Michael Certo, Ramesh Naidu Chatta, Lisa Michelle Cook, Joseph Corbett, Joseph Seth Cushing, Steven Paul Davidson, Shailesh Deshpande, Sevara Ergasheva, Maria Ervin, James Wilson Foy, Jr., Noel Mary Fuller, Benjamin Judson Gaines, III, Candace Gordon, Jesse Antonio Hernandez, Christine Hoagland, Robert Charles Hoard, Michael Spiro Karafotis, Wesley Keville, Sandip Kumar, Terri Dorinda Lail, Mukesh Maraj, Wyatt Edward Maxey, Dari Ann Mckenzie, Ashley Meadows, Heather Newell, Conor Mitchell Liam Nodzak, Kenyell Javon Ollie, Jayshree G. Patel, David John Perro, Nivetha Raghavan, Nikhil Ram, Tara Michel Ramirez, Laurie Readhead, Mary Kathleen Riley, Elizabeth Rachel Rock, Angela Dawn Roose, Sanjay Singeetham, Kyle S. Sorensen, Shreyas Srinivas, Constance Jones Suarez, Viresh Taskar, Linda Trent, Sachin Varule, Bradley Walton, Christie M. Weekley, Yvette Alston, Ravindra Bandaru, Carmen R. Barnhill, Jamie Gilchrist, Namrata Kaushik, Fernando A. Maisonett
  • PHANTOM FOR AN OPTOACOUSTIC PROBE AND METHOD OF MAKING THE SAME
    Publication number: 20230346226
    Abstract: A method for forming a phantom for an optoacoustic probe is provided that may include forming a scattering material. The method may also include forming an absorbing material, and mixing the scattering material with the absorbing material to form a tissue material. The method can also include mixing the tissue material with a urethane solution to form a phantom material, and curing the phantom material to form the phantom.
    Type: Application
    Filed: April 20, 2023
    Publication date: November 2, 2023
    Applicant: Seno Medical Instruments, Inc.
    Inventors: Tam Do, Jason Cook, Lisa Michelle Richards Cook
  • METHODS OF GROWING METAL-CONTAINING FILMS
    Publication number: 20230295803
    Abstract: Methods of forming metal-containing films for electronic devices (e.g., logic devices and/or memory devices) and methods for reducing equivalent oxide thickness (EOT) penalty in electronic devices are disclosed. The methods comprise exposing a substrate surface to a metal precursor, such as titanium chloride (TiCl4), a reducing agent, such as a cyclic 1,4-diene, and a reactant, ammonia (NH3), either simultaneously, partially simultaneously or separately and sequentially to form the metal-containing film.
    Type: Application
    Filed: April 14, 2023
    Publication date: September 21, 2023
    Applicant: Applied Materials, Inc.
    Inventors: Haoming Yan, Shih Chung Chen, Mandyam Sriram, EunKee Hong, Janardhan Devrajan, Lakmal C. Kalutarage, Yongjing Lin, Lisa Michelle Mandrell, Arkaprava Dan
  • Systems and methods for screening particle source manufacturing and development test data
    Patent number: 11719727
    Abstract: A computing system obtains test data for a particle source. The test data was generated by the particle source when the particle source was caused to emit particles. The test data comprises a first set of measurements of a first type and a second set of measurements of a second type. The computing system applies a data agnostic predictive model to the test data. The data agnostic predictive model is generated without a parametric analysis of variables of the first type and variables of the second type. The data agnostic predictive model outputs, based upon the test data, a value that is indicative of whether or not the test data is abnormal. Based upon the value, the computing system outputs an indication that the particle source was operating sub-optimally when emitting the particles.
    Type: Grant
    Filed: February 10, 2021
    Date of Patent: August 8, 2023
    Assignee: National Technology & Engineering Solutions of Sandia, LLC
    Inventors: Rosalie A. Multari, Jaideep Ray, Lisa Michelle Miller, Paul Girard Cummings, Jr., Robert Ferrizz, Lisa A. Walla, Nishant Bhupendra Patel, Shawn Martin, Curtis Co
  • OPTOACOUSTIC PROBE
    Publication number: 20220257193
    Abstract: An optoacoustic probe for optoacoustic imaging of a volume, the optoacoustic probe having a distal end operable to contact the volume and a proximal end. The optoacoustic probe includes at least one primary light source and an auxiliary light source that is configured to generate auxiliary light carried through an optical window to a volume. A detection device is configured to detect signals generated from the auxiliary light or primary light reflecting from the volume or the optical window. A microcontroller including one or more processors is also provided, that receives the signals generated from the auxiliary light reflecting from the volume from the detection device, determines contact between the volume and the optoacoustic probe based on the auxiliary light reflecting from the volume, and prevents the at least one primary light source from generating light until the optoacoustic probe is contacting the volume.
    Type: Application
    Filed: May 3, 2022
    Publication date: August 18, 2022
    Applicant: Seno Medical Instruments, Inc.
    Inventors: Jeffrey Nelson Harris, Tam Thien Do, Xavier Rey Saenz, Lisa Michelle Richards Cook
  • Optoacoustic probe
    Patent number: 11382565
    Abstract: An optoacoustic probe for optoacoustic imaging of a volume, the optoacoustic probe having a distal end operable to contact the volume and a proximal end. The optoacoustic probe includes at least one primary light source and an auxiliary light source that is configured to generate auxiliary light carried through an optical window to a volume. A detection device is configured to detect signals generated from the auxiliary light or primary light reflecting from the volume or the optical window. A microcontroller including one or more processors is also provided, that receives the signals generated from the auxiliary light reflecting from the volume from the detection device, determines contact between the volume and the optoacoustic probe based on the auxiliary light reflecting from the volume, and prevents the at least one primary light source from generating light until the optoacoustic probe is contacting the volume.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: July 12, 2022
    Assignee: Seno Medical Instruments, Inc.
    Inventors: Jeffrey Nelson Harris, Tam Thien Do, Xavier Rey Saenz, Lisa Michelle Richards Cook
  • System and method for tinting of computer-generated object(s)
    Patent number: 11328457
    Abstract: Described herein is a system and method for tinting of a computer-generated object. Selection of a target color to be applied to be an object is received. The target color can have a luminosity component and a chroma component (e.g., the luminosity, hue, chroma (LHC) color space). Based, at least in part, upon at least one of the luminosity component or the chroma component of the target color, one or more tinting methods of a plurality of tinting methods is selected to tint the object to the target color. The object can be tinted using the selected one or more tinting methods, and, the tinted object provided (e.g., stored and/or displayed to a user via a graphical user interface).
    Type: Grant
    Filed: November 7, 2019
    Date of Patent: May 10, 2022
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Lisa Michelle Hazen, Dylan Michael Piepenbrok, Sarah Lynn Kisor
  • Polymorphic compounds and uses thereof
    Patent number: 11324769
    Abstract: The present invention provides compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.
    Type: Grant
    Filed: July 28, 2020
    Date of Patent: May 10, 2022
    Assignee: Astrocyte Pharmaceuticals, Inc.
    Inventors: Russell Birch Poe, David T. Jonaitis, Lisa Michelle Grove
  • CONSOLIDATED DATA RESTORATION FRAMEWORK
    Publication number: 20220004465
    Abstract: Embodiments of the present invention provide a system for identifying occurrence of events and performing one or more actions to mitigate the impacts of the events. The system is configured for gathering data from one or more data sources of an entity, generating dataflows using the data gathered from the one or more data sources, identifying an anomaly based on one or more indicators and the dataflows, determining occurrence of an event and generating one or more propagation models associated with the event, performing event impact analysis based on the one or more propagation models, perform one or more actions to contain the event based on the one or more propagation models, identifying a last good copy of data based on the data gathered from the one or more data sources, retrieving the last good copy of data, and restoring the last good copy of data.
    Type: Application
    Filed: July 6, 2021
    Publication date: January 6, 2022
    Applicant: BANK OF AMERICA CORPORATION
    Inventors: Christopher Emmanuel Huntley, Musa Ajakaiye, Prasad V. Annadata, Dnyanesh P. Ballikar, Sina Bauer, Jason Kenneth Bellew, Timothy John Bendel, David Alan Beumer, Michelle Andrea Boston, Lisa Julia Brown, Robin J. Buck, Brian C. Busch, Salvatore Michael Certo, Ramesh Naidu Chatta, Lisa Michelle Cook, Joseph Corbett, Joseph Seth Cushing, Steven Paul Davidson, Shailesh Deshpande, Sevara Ergasheva, Maria Ervin, James Wilson Foy, JR., Noel Mary Fuller, Benjamin Judson Gaines, III, Candace Gordon, Jesse Antonio Hernandez, Christine Hoagland, Robert Charles Hoard, Michael Spiro Karafotis, Wesley Keville, Sandip Kumar, Terri Dorinda Lail, Mukesh Maraj, Wyatt Edward Maxey, Dari Ann McKenzie, Ashley Meadows, Heather Newell, Conor Mitchell Liam Nodzak, Kenyell Javon Ollie, Jayshree G. Patel, David John Perro, Nivetha Raghavan, Nikhil Ram, Tara Michel Ramirez, Laurie Readhead, Mary Kathleen Riley, Elizabeth Rachel Rock, Angela Dawn Roose, Sanjay Singeetham, Kyle S. Sorensen, Shreyas Srinivas, Constance Jones Suarez, Viresh Taskar, Linda Trent, Sachin Varule, Bradley Walton, Christie M. Weekley, Yvette Alston, Ravi K. Bandaru, Carmen R. Barnhill, Joseph Benet, Jamie Gilchrist, Namrata Kaushik, Fernando A. Maisonett
  • Methods and Systems for Determining Body Composition of Biological Bodies Using a Resonant Cavity
    Publication number: 20210321900
    Abstract: Systems and methods for generating a body composition measurement of a biological body include a resonant cavity, antennae used to measure resonance of the empty cavity and a biological body in the cavity, a network analyzer, and a controller configured to generate a body composition measurement based on the resonance measurements. The body composition measurement is used to determine risk assessments of developing metabolic disease, particularly for children, based on body fat composition. Height, weight, and body shape are also measured by the systems and methods to contribute to the risk assessment.
    Type: Application
    Filed: April 13, 2021
    Publication date: October 21, 2021
    Inventor: Lisa Michelle Kotowski
  • POLYMORPHIC COMPOUNDS AND USES THEREOF
    Publication number: 20210077518
    Abstract: The present invention provides compounds and methods of use thereof for treatment of certain disorders and conditions, for example brain injuries such as stroke or traumatic brain injuries.
    Type: Application
    Filed: July 28, 2020
    Publication date: March 18, 2021
    Inventors: Russell Birch POE, David T. JONAITIS, Lisa Michelle GROVE
  • A System and Method for Tinting of Computer-Generated Object(s)
    Publication number: 20210074032
    Abstract: Described herein is a system and method for tinting of a computer-generated object. Selection of a target color to be applied to be an object is received. The target color can have a luminosity component and a chroma component (e.g., the luminosity, hue, chroma (LHC) color space). Based, at least in part, upon at least one of the luminosity component or the chroma component of the target color, one or more tinting methods of a plurality of tinting methods is selected to tint the object to the target color. The object can be tinted using the selected one or more tinting methods, and, the tinted object provided (e.g., stored and/or displayed to a user via a graphical user interface).
    Type: Application
    Filed: November 7, 2019
    Publication date: March 11, 2021
    Applicant: Microsoft Technology Licensing, LLC
    Inventors: Lisa Michelle HAZEN, Dylan Michael PIEPENBROK, Sarah Lynn KISOR
  • OPTOACOUSTIC PROBE
    Publication number: 20210022680
    Abstract: An optoacoustic probe for optoacoustic imaging of a volume, the optoacoustic probe having a distal end operable to contact the volume and a proximal end. The optoacoustic probe includes at least one primary light source and an auxiliary light source that is configured to generate auxiliary light carried through an optical window to a volume. A detection device is configured to detect signals generated from the auxiliary light or primary light reflecting from the volume or the optical window. A microcontroller including one or more processors is also provided, that receives the signals generated from the auxiliary light reflecting from the volume from the detection device, determines contact between the volume and the optoacoustic probe based on the auxiliary light reflecting from the volume, and prevents the at least one primary light source from generating light until the optoacoustic probe is contacting the volume.
    Type: Application
    Filed: July 22, 2019
    Publication date: January 28, 2021
    Applicant: Seno Medical Instruments, Inc.
    Inventors: Jeffrey Nelson Harris, Tam Thien Do, Xavier Rey Saenz, Lisa Michelle Richards Cook