Patents by Inventor Lisa Minor

Lisa Minor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of measuring the biological activity of an urotensin II receptor
    Patent number: 7939052
    Abstract: Administration of U-II to rats caused an increase in the redness or the skin temperature of the ear of the rats. The increase was inhibited by compounds that decease the biological activity of the U-II/UT receptor. Thus, the present invention provides methods of measuring the biological activity of an U-II receptor by monitoring the redness or the skin temperature of the ear of an animal, and the use of the methods to test compounds for their abilities to increase or decrease the biological activity of an U-II receptor.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: May 10, 2011
    Assignee: Janssen Pharmaceutica NV
    Inventors: Robert Schulingkamp, Jianshen Qi, Raymond Colburn, Dennis Stone, Christopher Van Besien, Lisa Minor, Patricia Andrade-Gordon, Bruce Damiano
  • Human cell clones having an endogeneous urotensin II receptor
    Patent number: 7892826
    Abstract: Human cell clones with increased specific binding to urotensin II have been sub-cloned from SJRH30 (ATCC® Number: CRL-2061™). These cell clones have been used for functional analyses of the biological activity of an endogeneous urotensin II receptor, as well as for identifying compounds that regulate the biological activity of an Urotensin II receptor.
    Type: Grant
    Filed: August 9, 2006
    Date of Patent: February 22, 2011
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Lisa Minor, Jenson Qi, Yuanping Wang
  • Method of measuring the biological activity of an urotensin II receptor
    Publication number: 20070087326
    Abstract: Administration of U-II to a cell having a functional urotensin II receptor caused an increase in the electrical impedance of the cell in a receptor specific and dose dependent manner. Thus, the present invention provides methods of measuring the biological activity of an U-II receptor by monitoring the electrical impedance of the cell, and the use of the methods to identify a cell having a functional U-II receptor, as well as to identify compounds that increase or decrease the biological activity of an U-II receptor.
    Type: Application
    Filed: August 10, 2006
    Publication date: April 19, 2007
    Inventors: Lisa Minor, Jenson Qi, Yuanping Wang
  • Human cell clones useful for functional analyses of the biological activity of an endogeneous urotensin II receptor and uses thereof
    Publication number: 20070082368
    Abstract: Human cell clones with increased specific binding to urotensin II have been sub-cloned from SJRH30 (ATCC® Number: CRL-2061™). These cell clones have been used for functional analyses of the biological activity of an endogeneous urotensin II receptor, as well as for identifying compounds that regulate the biological activity of an Urotensin II receptor.
    Type: Application
    Filed: August 9, 2006
    Publication date: April 12, 2007
    Inventors: Lisa Minor, Jenson Qi, Yuanping Wang
  • Method of measuring the biological activity of an urotensin II receptor
    Publication number: 20060280686
    Abstract: Administration of U-II to rats caused an increase in the redness or the skin temperature of the ear of the rats. The increase was inhibited by compounds that decease the biological activity of the U-II/UT receptor. Thus, the present invention provides methods of measuring the biological activity of an U-II receptor by monitoring the redness or the skin temperature of the ear of an animal, and the use of the methods to test compounds for their abilities to increase or decrease the biological activity of an U-II receptor.
    Type: Application
    Filed: May 11, 2006
    Publication date: December 14, 2006
    Inventors: Robert Schulingkamp, Jianshen Qi, Raymond Colburn, Dennis Stone, Christopher Van Besien, Lisa Minor, Patricia Andrade-Gordon, Bruce Damiano