Patents by Inventor Lisa Molz

Lisa Molz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl Rheb inhibitors and uses thereof
    Patent number: 11339144
    Abstract: The present invention provides compounds of general Formula I and I?: compositions thereof, and methods of using same to treat Rheb-mediated disorders.
    Type: Grant
    Filed: April 9, 2018
    Date of Patent: May 24, 2022
    Assignee: NAVITOR PHARMACEUTICALS, INC.
    Inventors: Sarah Mahoney, Lisa Molz, Sridhar Narayan, Eddine Saiah
  • HETEROARYL RHEB INHIBITORS AND USES THEREOF
    Publication number: 20210238165
    Abstract: The present invention provides compounds, compositions thereof, and methods of using the same. Compositions comprising a compound of this invention or a pharmaceutically acceptable derivative thereof and a pharmaceutically acceptable carrier, adjuvant, or vehicle. The amount of the compound in compositions of this invention is such that it is effective to measurably inhibit Rheb, in a biological sample or in a patient.
    Type: Application
    Filed: April 9, 2018
    Publication date: August 5, 2021
    Inventors: Sarah MAHONEY, Lisa MOLZ, Sridhar NARAYAN, Eddine SAIAH
  • Methods and reagents for amplification and manipulation of vector and target nucleic acid sequences
    Publication number: 20030082559
    Abstract: The invention provides methods and compositions for the amplification of vector sequences, particularly for amplification of vectors applied to the elucidation of mammalian gene function. The present invention relates to methods and compositions for recovery/amplification of DNA sequences from mammalian complementation screening products, products of the functional inactivation of specific essential or non-essential mammalian genes, and products from the identification of mammalian genes which are modulated in response to specific stimuli.
    Type: Application
    Filed: January 22, 2002
    Publication date: May 1, 2003
    Inventors: David Beach, Lisa Molz, Mark Caddle
  • Polynucleotides encoding phosphatidylinositol 3-kinases
    Patent number: 6291220
    Abstract: The present invention generally provides nucleic acids and polypeptides that are phosphatidylinositol 3-kinases, also known as 1-phosphatidylinositol 3-kinases. The nuclecic acids and polypeptides disclosed are derived from Drosophila and mouse. These polypeptides are generally involved in cell signaling cascades which control, e.g., cell cycle progression and intracellular protein sorting. The family of PI3-kinases from which the polypeptides of the invention are derived are generally characterized by their structure as well as their unique substrate specificity.
    Type: Grant
    Filed: October 13, 1998
    Date of Patent: September 18, 2001
    Assignee: The Regents of the University of California
    Inventors: Lewis T. Williams, Lisa Molz, Yen-Wen Chen
  • PI 3-kinase polypeptides
    Patent number: 5948664
    Abstract: The present invention generally provides polypeptides that are related to and/or derived from the family of PI3-kinases. These polypeptides are generally involved in cell signaling cascades which control, e.g., cell cycle progression and intracellular protein sorting. The family of PI3-kinases from which the polypeptides of the invention are derived are generally characterized by their structure as well as their unique substrate specificity.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: September 7, 1999
    Assignee: The Regents of the University of California
    Inventors: Lewis T. Williams, Lisa Molz, Yen-Wen Chen