Patents by Inventor Lisa N. Kasiewicz

Lisa N. Kasiewicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
    Publication number: 20240131166
    Abstract: Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.
    Type: Application
    Filed: September 19, 2023
    Publication date: April 25, 2024
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Alexandra Chadwick, Caroline Reiss
  • COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
    Publication number: 20240100169
    Abstract: Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.
    Type: Application
    Filed: September 19, 2023
    Publication date: March 28, 2024
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Alexandra Chadwick, Caroline Reiss
  • LIPID FORMULATIONS FOR GENE EDITING
    Publication number: 20240010609
    Abstract: The present disclosure relates to PEG-lipids, cationic and/or ionizable lipids and nucleic acid-lipid particle compositions comprising the same. The present disclosure also relates to methods of making, using and delivering the described lipids and lipid-containing particles.
    Type: Application
    Filed: March 8, 2023
    Publication date: January 11, 2024
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Aaron Beach, Thomas V., Colace
  • Compositions and methods for targeted RNA delivery
    Patent number: 11801306
    Abstract: Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.
    Type: Grant
    Filed: November 23, 2021
    Date of Patent: October 31, 2023
    Assignee: Verve Therapeutics, Inc.
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Alexandra Chadwick, Caroline Reiss
  • COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
    Publication number: 20220152210
    Abstract: Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.
    Type: Application
    Filed: November 23, 2021
    Publication date: May 19, 2022
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Alexandra Chadwick, Caroline Reiss
  • Compositions and methods for targeted RNA delivery
    Patent number: 11207416
    Abstract: Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.
    Type: Grant
    Filed: March 4, 2021
    Date of Patent: December 28, 2021
    Assignee: Verve Therapeutics, Inc.
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Alexandra Chadwick, Caroline Reiss
  • COMPOSITIONS AND METHODS FOR TARGETED RNA DELIVERY
    Publication number: 20210299261
    Abstract: Provided herein are compositions, methods of making the same, and methods for targeted delivery of therapeutic agents for modifying expression and function of target genes, e.g. proteins involved in lipid and cholesterol metabolism such as PCSK9. Further provided herein are compositions and methods of treating conditions related to coronary disease.
    Type: Application
    Filed: March 4, 2021
    Publication date: September 30, 2021
    Inventors: Kallanthottathil G. Rajeev, Souvik Biswas, Padma Malyala, Lisa N. Kasiewicz, Alexandra Chadwick, Caroline Reiss