Patents by Inventor Lisa Nagy

Lisa Nagy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for determining crystallization parameters and apparatus for use with the same
    Patent number: 8304241
    Abstract: The present disclosure provides a method to allow a user to pre-screen numerous crystallization conditions in the crystallization space to identify those conditions with the highest probability of yielding crystals and high quality diffracting crystals. In one embodiment, the dilute solution thermodynamic virial coefficient, termed B, is used to aid in the determination crystallization conditions that increase the probability of producing crystals for the crystallant of interest. The present disclosure also provide methods for predicting solution conditions that generate beneficial solubility and/or stability conditions for a polypeptide of interest using the B parameter. Devices for use in the described methods are also described.
    Type: Grant
    Filed: November 30, 2011
    Date of Patent: November 6, 2012
    Assignees: The UAB Research Foundation, Colorado State University Research Foundation, Mississippi State University
    Inventors: Lawrence J DeLucas, Wilbur W Wilson, Charles S Henry, Lisa Nagy, David Johnson
  • METHOD FOR DETERMINING CRYSTALLIZATION PARAMETERS AND APPARATUS FOR USE WITH THE SAME
    Publication number: 20120077248
    Abstract: The present disclosure provides a method to allow a user to pre-screen numerous crystallization conditions in the crystallization space to identify those conditions with the highest probability of yielding crystals and high quality diffracting crystals. In one embodiment, the dilute solution thermodynamic virial coefficient, termed B, is used to aid in the determination crystallization conditions that increase the probability of producing crystals for the crystallant of interest. The present disclosure also provide methods for predicting solution conditions that generate beneficial solubility and/or stability conditions for a polypeptide of interest using the B parameter. Devices for use in the described methods are also described.
    Type: Application
    Filed: November 30, 2011
    Publication date: March 29, 2012
    Inventors: Lawrence J. DeLucas, Wilbur W. Wilson, Tom Lewis, Ken Banaslewlcz, Lisa Nagy, David Johnson, Charles S. Henry
  • Method for determining crystallization parameters and apparatus for use with the same
    Patent number: 8080421
    Abstract: The present disclosure provides a method to allow a user to pre-screen numerous crystallization conditions in the crystallization space to identify those conditions with the highest probability of yielding crystals and high quality diffracting crystals. In one embodiment, the dilute solution thermodynamic virial coefficient, termed B, is used to aid in the determination crystallization conditions that increase the probability of producing crystals for the crystallant of interest. The present disclosure also provide methods for predicting solution conditions that generate beneficial solubility and/or stability conditions for a polypeptide of interest using the B parameter. Devices for use in the described methods are also described.
    Type: Grant
    Filed: November 13, 2007
    Date of Patent: December 20, 2011
    Assignees: The UAB Research Foundation, Mississippi State University, Colorado State University Research Foundation
    Inventors: Lawrence J. DeLucas, Wilbur W. Wilson, Lisa Nagy, David Johnson, Charles S. Henry
  • METHOD FOR DETERMINING CRYSTALLIZATION PARAMETERS AND APPARATUS FOR USE WITH THE SAME
    Publication number: 20090042743
    Abstract: The present disclosure provides a method to allow a user to pre-screen numerous crystallization conditions in the crystallization space to identify those conditions with the highest probability of yielding crystals and high quality diffracting crystals. In one embodiment, the dilute solution thermodynamic virial coefficient, termed B, is used to aid in the determination crystallization conditions that increase the probability of producing crystals for the crystallant of interest. The present disclosure also provide methods for predicting solution conditions that generate beneficial solubility and/or stability conditions for a polypeptide of interest using the B parameter. Devices for use in the described methods are also described.
    Type: Application
    Filed: November 13, 2007
    Publication date: February 12, 2009
    Inventors: Lawrence J. DeLucas, Wilbur W. Wilson, Tom Lewis, Ken Banasiewicz, Lisa Nagy, David Johnson, Charles S. Henry