Patents by Inventor Lisa Polin
Lisa Polin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8183379Abstract: The invention provides compounds of formula I: wherein Y is F or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof, and methods of inhibiting cancer cells.Type: GrantFiled: November 14, 2008Date of Patent: May 22, 2012Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Lisa Polin, Stuart T. Hazeldine, Thomas H. Corbett
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Patent number: 7728007Abstract: The invention provides compounds of the formula: wherein X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.Type: GrantFiled: October 29, 2008Date of Patent: June 1, 2010Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Thomas H. Corbett, Eduardo Palomino, Lisa Polin, Stuart T. Hazeldine
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Patent number: 7585863Abstract: The invention provides compounds of the formula: wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.Type: GrantFiled: August 31, 2006Date of Patent: September 8, 2009Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Thomas H. Corbett, Eduardo Palomino, Lisa Polin, Stuart T. Hazeldine
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Patent number: 7507749Abstract: The invention provides compounds of formula I: wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agent. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: GrantFiled: May 24, 2007Date of Patent: March 24, 2009Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Stuart T. Hazeldine, Thomas H. Corbett, Lisa Polin
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Publication number: 20090076073Abstract: The invention provides compounds of the formula: wherein X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.Type: ApplicationFiled: October 29, 2008Publication date: March 19, 2009Inventors: Jerome P. Horwitz, Thomas H. Corbett, Eduardo Palomino, Lisa Polin, Stuart T. Hazeldine
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Publication number: 20090069372Abstract: The invention provides compounds of formula I: wherein Y is F or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof, and methods of inhibiting cancer cells.Type: ApplicationFiled: November 14, 2008Publication date: March 12, 2009Inventors: Jerome P. Horwitz, Lisa Polin
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Patent number: 7470788Abstract: The invention provides compounds of formula I: wherein Y is F, Cl or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: GrantFiled: September 9, 2005Date of Patent: December 30, 2008Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Lisa Polin, Stuart T. Hazeldine, Thomas H. Corbett
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Publication number: 20070232643Abstract: The invention provides compounds of formula I: wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salt thereof. The compounds are effective antitumor agent. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: ApplicationFiled: May 24, 2007Publication date: October 4, 2007Inventors: Jerome Horwitz, Stuart Hazeldine, Thomas Corbett, Lisa Polin
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Patent number: 7241894Abstract: The invention provides compounds of formula I: wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: GrantFiled: December 10, 2004Date of Patent: July 10, 2007Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Stuart T. Hazeldine, Thomas H. Corbett, Lisa Polin
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Publication number: 20070060612Abstract: The invention provides compounds of formula I: wherein Y is F, Cl or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: ApplicationFiled: September 9, 2005Publication date: March 15, 2007Inventors: Jerome Horwitz, Lisa Polin
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Publication number: 20070054938Abstract: The invention provides compounds of formula I: wherein Y is F, Cl or Br; or a pharmaceutically acceptable salt thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: ApplicationFiled: September 7, 2005Publication date: March 8, 2007Inventors: Jerome Horwitz, Lisa Polin, Stuart Hazeldine, Thomas Corbett
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Publication number: 20060293333Abstract: The invention provides compounds of the formula: wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.Type: ApplicationFiled: August 31, 2006Publication date: December 28, 2006Inventors: Jerome Horwitz, Thomas Corbett, Eduardo Palomino, Lisa Polin, Stuart Hazeldine
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Patent number: 7109341Abstract: The invention provides compounds of the formula: wherein A, X, Y, and Z are as defined in the specification. The compounds are effective anti-tumor agents. The invention also provides pharmaceutical compositions comprising a compound of the above formula or a salt thereof, intermediates useful for preparing a compound of the above formula, and therapeutic methods comprising administering a compound of the above formula or a salt thereof to a mammal in need thereof.Type: GrantFiled: July 3, 2003Date of Patent: September 19, 2006Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Thomas H. Corbett, Eduardo Palomino, Lisa Polin, Stuart T. Hazeldine
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Publication number: 20050159447Abstract: The invention provides compounds of formula I: wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: ApplicationFiled: December 10, 2004Publication date: July 21, 2005Inventors: Jerome Horwitz, Stuart Hazeldine, Thomas Corbett, Lisa Polin
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Patent number: 6867219Abstract: The invention provides compounds of formula I: wherein Y is F, Cl, Br, methyl or methoxy; and pharmaceutically acceptable salts thereof. The compounds are effective antitumor agents. The invention also provides pharmaceutical compositions comprising a compound of formula I or a salt thereof, intermediates useful for preparing a compound of formula I, and therapeutic methods comprising administering a compound of formula I or a salt thereof to a mammal in need thereof.Type: GrantFiled: July 31, 2002Date of Patent: March 15, 2005Assignee: Wayne State UniversityInventors: Jerome P. Horwitz, Stuart T. Hazeldine, Thomas H. Corbett, Lisa Polin
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Publication number: 20040132618Abstract: The invention provides compounds of the formula: 1Type: ApplicationFiled: July 3, 2003Publication date: July 8, 2004Inventors: Jerome P. Horwitz, Thomas H. Corbett, Eduardo Palomino, Lisa Polin, Stuart T. Hazeldine
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Publication number: 20030144321Abstract: The invention provides compounds of formula I: 1Type: ApplicationFiled: July 31, 2002Publication date: July 31, 2003Inventors: Jerome P. Horwitz, Stuart T. Hazeldine, Thomas H. Corbett, Lisa Polin
