Patents by Inventor Lisa R. Braun

Lisa R. Braun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for purification of nucleic acid from a host cell
    Patent number: 7863050
    Abstract: Methods and compositions are provided for gently lysing and solubilizing cells. Methods and compositions are further provided for quickly purifying high quality low molecular weight nucleic acid from host cells. Target cells are treated with a pre-chilled lysis solution having a zwitterionic detergent, for example n-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate, and a brief room-temperature incubation. Where nucleic acid purification is required, the lysis solution-treated cells are contacted with a nucleic acid capture matrix having an average pore size of at least about 1 ?m.
    Type: Grant
    Filed: January 22, 2009
    Date of Patent: January 4, 2011
    Assignee: Qiagen North American Holdings, Inc.
    Inventors: Michael J. Domanico, Matt Myers, Kristian Keane, Lisa R. Braun, Thomas Kolzau
  • Methods and Compositions for Purification of Nucleic Acid from a Host Cell
    Publication number: 20090246859
    Abstract: Methods and compositions are provided for gently lysing and solubilizing cells. Methods and compositions are further provided for quickly purifying high quality low molecular weight nucleic acid from host cells. Target cells are treated with a pre-chilled lysis solution having a zwitterionic detergent, for example n-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate, and a brief room-temperature incubation. Where nucleic acid purification is required, the lysis solution-treated cells are contacted with a nucleic acid capture matrix having an average pore size of at least about 1 ?m.
    Type: Application
    Filed: January 22, 2009
    Publication date: October 1, 2009
    Applicant: Qiagen North American Holdings, Inc.
    Inventors: Michael J. Domanico, Matt Meyers, Kristian Keane, Lisa R. Braun, Thomas Kolzau
  • Methods and compositions for purification of nucleic acid from a host cell
    Publication number: 20040180445
    Abstract: Methods and compositions are provided for gently lysing and solubilizing cells. Methods and compositions are further provided for quickly purifying high quality low molecular weight nucleic acid from host cells. Target cells are treated with a pre-chilled lysis solution having a zwitterionic detergent, for example n-Dodecyl-N,N-dimethyl-3-ammonio-1-propanesulfonate, and a brief room-temperature incubation. Where nucleic acid purification is required, the lysis solution-treated cells are contacted with a nucleic acid capture matrix having an average pore size of at least about 1 &mgr;m.
    Type: Application
    Filed: March 12, 2003
    Publication date: September 16, 2004
    Inventors: Michael J. Domanico, Matt Meyers, Kristian Keane, Lisa R. Braun, Thomas Kolzau