Abstract: A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer. Administration of an OSM antagonist such as a small molecule pharmaceutical is provided as well as an anti-OSM antibody, an anti-OSM aptamer, and an OSM mRNA antagonist. The OSM antagonists were found to inhibit or prevent tumor cell detachment, progression, proliferation and metastasis in several cancer types.

Abstract: A method of treating cancer or metastasis is provided involving administering at least one oncostatin M (OSM) antagonist to a subject, wherein the subject has been diagnosed with cancer. Administration of an OSM antagonist such as a small molecule pharmaceutical is provided as well as an anti-OSM antibody, an anti-OSM aptamer, and an OSM mRNA antagonist. The OSM antagonists were found to inhibit or prevent tumor cell detachment, progression, proliferation and metastasis in several cancer types.

Abstract: An apparatus may be adaptable for laboratory, field, or in vivo detection and measurement of benzene, benzenoids, or other organic molecules or compounds. A selective binding agent is created by binding a target molecule or similar molecule with an appropriate monomer, polymerizing the monomer, and removing the target or similar molecule. This procedure results in binding agent sites that are highly selective for the target molecule over other similar organic molecules. The finished binding agent is coated onto or otherwise incorporated with an electrode. The size of the electrode diameter may range from a scale of inches to a scale of sub micrometers, depending on the application. In preferred embodiments, polymers templated with a derivatized benzene molecule have shown to be effective even for detection and measurement of benzene, which is non-electroreactive.