Patents by Inventor Lise Brown Christiansen

Lise Brown Christiansen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Urea glucokinase activators
    Patent number: 8362049
    Abstract: This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composition comprising a compound according to the invention and a process for preparing such.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: January 29, 2013
    Assignee: Novo Nordisk A/S
    Inventors: Anthony Murray, Jesper Lau, Per Vedsoe, Lise Brown Christiansen
  • Urea glucokinase activators
    Patent number: 8318778
    Abstract: This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composition comprising a compound according to the invention and a process for preparing such.
    Type: Grant
    Filed: January 8, 2008
    Date of Patent: November 27, 2012
    Assignee: Novo Nordisk A/S
    Inventors: Anthony Murray, Jesper Lau, Per Vedsø, Lise Brown Christiansen
  • Urea Glucokinase Activators
    Publication number: 20120165375
    Abstract: This application relates to novel urea glucokinase activators and use of the compounds of the invention for preparation of a medicament for the treatment of various diseases, e.g. for the treatment of type 2 diabetes. Further encompassed is a pharmaceutical composition comprising a compound according to the invention and a process for preparing such.
    Type: Application
    Filed: March 8, 2012
    Publication date: June 28, 2012
    Applicant: Novo Nordisk A/S
    Inventors: Anthony Murray, Jasper Lau, Per Vedsø, Lise Brown Christiansen
  • 2-(2-hydroxyphenyl) benzothiadiazines useful for treating obesity and diabetes
    Patent number: 8022066
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: September 20, 2011
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Anders Klarskov Petersen, Preben Houlberg Olesen, Lise Brown Christiansen, Holger Claus Hansen, Flemming Elmelund Nielsen
  • Haloalkylsulfone substituted compounds useful for treating obesity and diabetes
    Patent number: 7939690
    Abstract: The present invention relates to novel compounds of formula [I], wherein R1 represents heteroaryl, at least one substituent among R5, R6 and R7 represent —SR12, —S(O)R12 or —S(O)2R12 and the remaining substituents are as defined in the claims, that act as chemical uncouplers. Compounds of the invention are useful inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases associated therewith.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: May 10, 2011
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Anders Klarskov Petersen, Preben Houlberg Olesen, Lise Brown Christiansen, Flemming Elmelund Nielsen
  • 2-(2-hydroxyphenyl)benzimidazoles useful for treating obesity and diabetes
    Patent number: 7915299
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
    Type: Grant
    Filed: November 15, 2007
    Date of Patent: March 29, 2011
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Anders Klarskov Petersen, Preben Houlberg Olesen, Lise Brown Christiansen, Holger Claus Hansen, Flemming Elmelund Nielsen
  • 2- ( 2 -HYDROXYPHENYL) -QUINAZOLIN-4-ONES USEFUL FOR TREATING OBESITY AND DIABETES
    Publication number: 20100249161
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
    Type: Application
    Filed: November 15, 2007
    Publication date: September 30, 2010
    Inventors: Anders Klarskov Petersen, Preben Houlberg Olesen, Lise Brown Christiansen, Holger Claus Hansen, Flemming Elmelund Nielsen
  • HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES
    Publication number: 20100113536
    Abstract: The present invention relates to novel compounds of formula [I], wherein R1 represents heteroaryl, at least one substituent among R5, R6 and R7 represent —SR12, —S(O)R12 or —S(O)2R12 and the remaining substituents are as defined in the claims, that act as chemical uncouplers. Compounds of the invention are useful inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases associated therewith.
    Type: Application
    Filed: November 15, 2007
    Publication date: May 6, 2010
    Inventors: Anders Klarskov Petersen, Preben Houlberg Olesen, Lise Brown Christiansen, Flemming Elmelund Nielsen
  • NOVEL SALICYLIC ANILIDES
    Publication number: 20100075932
    Abstract: Novel salicylic anilides are chemical uncouplers useful e.g. for the treatment of obesity.
    Type: Application
    Filed: November 24, 2009
    Publication date: March 25, 2010
    Applicant: HIGH POINT PHARMACEUTICALS, LLC
    Inventors: Preben Olesen, Thomas Kruse Hansen, Lise Brown Christiansen, Holger Claus Hansen
  • NOVEL 2-(2-HYDROXYPHENYL)BENZIMlDAZOLES USEFUL FOR TREATING OBESITY AND DIABETES
    Publication number: 20100063122
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
    Type: Application
    Filed: November 15, 2007
    Publication date: March 11, 2010
    Inventors: Anders Klarskov Peterson, Preben Houlberg Olesen, Lise Brown Christiansen, Holger Claus Hansen, Flemming Elmelund Nielsen
  • HALOALKYLSULFONE SUBSTITUTED COMPOUNDS USEFUL FOR TREATING OBESITY AND DIABETES
    Publication number: 20100041657
    Abstract: The present invention relates to compounds of formula I, in which at least one of R5, R6 and R7 is SR12, S(O)R12 or S(O)2R12 group where R12 is a C1-6haloalkyl group, that act, as chemical uncouplers. Compounds of the invention are useful in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
    Type: Application
    Filed: May 11, 2006
    Publication date: February 18, 2010
    Applicant: NOVO NORDICK A/S
    Inventors: Preben Houlberg Olesen, Holger Claus Hansen, Lise Brown Christiansen, Flemming Elmelund Nielsen, Anders Klarskov Petersen
  • Salicylic anilides
    Patent number: 7645791
    Abstract: Novel salicylic anilides are chemical uncouplers useful e.g. for the treatment of obesity.
    Type: Grant
    Filed: June 27, 2008
    Date of Patent: January 12, 2010
    Assignee: High Point Pharmaceuticals, LLC
    Inventors: Preben Houlberg Olesen, Thomas Kruse Hansen, Lise Brown Christiansen, Holger Claus Hansen
  • NOVEL 2-(2-HYDROXYPHENYL) BENZOTHIADIAZINES USEFUL FOR TREATING OBESITY AND DIABETES
    Publication number: 20090325941
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful, inter alia, in the treatment, including prevention, of obesity, diabetes and a number of diseases or conditions associated therewith.
    Type: Application
    Filed: November 15, 2007
    Publication date: December 31, 2009
    Inventors: Anders Klarskov Petersen, Preben Houlberg Olesen, Lise Brown Christiansen, Holger Claus Hansen, Flemming Elmelund Nielsen
  • Novel Haloalkoxy-Substituted Salicylic Anilides
    Publication number: 20090062396
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful in the treatment, including prevention, of obesity, diabetes and a number of diseases or disorders associated therewith.
    Type: Application
    Filed: May 23, 2006
    Publication date: March 5, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Preben Houlberg Olesen, Holger Claus Hansen, Lise Brown Christiansen, Anders Klarskov Petersen, Flemming Elmelund Nielsen, Birgit Sehested Hansen
  • Novel Salicylic Anilides
    Publication number: 20090005434
    Abstract: Novel salicylic anilides are chemical uncouplers useful e.g. for the treatment of obesity.
    Type: Application
    Filed: June 27, 2008
    Publication date: January 1, 2009
    Applicant: Novo Nordisk A/S
    Inventors: Preben Houlberg Olesen, Thomas Kruse Hansen, Lise Brown Christiansen, Holger Claus Hansen
  • Sulfonamide Derivatives
    Publication number: 20080255240
    Abstract: Novel sulfon amide derivatives are chemical uncouplers useful e.g. for the treatment of obesity.
    Type: Application
    Filed: May 4, 2005
    Publication date: October 16, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Lise Brown Christiansen, Preben Houlberg Olesen, Holger Claus Hansen
  • Novel Trifluoromethoxy-Substituted Aryl Anilides
    Publication number: 20080234381
    Abstract: The present invention relates to novel compounds that act as chemical uncouplers. Compounds of the invention are useful in the treatment, including prevention, of obesity, diabetes and a number of diseases or disorders associated therewith.
    Type: Application
    Filed: May 23, 2006
    Publication date: September 25, 2008
    Applicant: Novo Nordisk A/S
    Inventors: Preben Houlberg Olesen, Holger Claus Hansen, Lise Brown Christiansen, Anders Klarskov Petersen, Flemming Elmelund Nielsen, Birgit Sehested Hansen
  • Heterocyclic compounds, which are inhibitors of the enzyme DPP-IV
    Patent number: 7235538
    Abstract: The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV, which are of formula I wherein each n is one or two independently and R1, R2, R3, R6, R7, R9, and R10 are defined herein. The present invention also relates to pharmaceutical compositions comprising the compounds of formula I and the use of the compounds for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type-2 diabetes and obesity.
    Type: Grant
    Filed: July 17, 2003
    Date of Patent: June 26, 2007
    Assignee: Novo Nordisk A/S
    Inventors: Anders Bendtz Kanstrup, Lise Brown Christiansen, Jane Marie Lundbeck, Christian K. Sams, Marit Kristiansen
  • Heterocyclic compounds that are inhibitors of the enzyme DPP-IV
    Patent number: 7192952
    Abstract: The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV of formula I, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity
    Type: Grant
    Filed: March 2, 2005
    Date of Patent: March 20, 2007
    Assignee: Novo Nordisk, A/S
    Inventors: Anders Bendtz Kanstrup, Christian Klarner Sams, Jane Marie Lundbeck, Lise Brown Christiansen, Marit Kristiansen
  • Heterocyclic compounds that are inhibitors of the enzyme DPP-IV
    Patent number: 6869947
    Abstract: The present invention relates to therapeutically active and selective inhibitors of the enzyme DPP-IV of formula I, pharmaceutical compositions comprising the compounds and the use of such compounds for and the manufacture of medicaments for treating diseases that are associated with proteins that are subject to inactivation by DPP-IV, such as type 2 diabetes and obesity
    Type: Grant
    Filed: June 28, 2002
    Date of Patent: March 22, 2005
    Assignee: Novo Nordisk A/S
    Inventors: Anders Bendtz Kanstrup, Christian Klarner Sams, Jane Marie Lundbeck, Lise Brown Christiansen, Marit Kristiansen