Patents by Inventor Lise Lund
Lise Lund has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240139173Abstract: The present invention provides a reproxalap ophthalmic solution, and methods of using the same for treating a disease or disorder such as allergic conjunctivitis.Type: ApplicationFiled: September 12, 2023Publication date: May 2, 2024Inventors: David CLARK, Susan MACDONALD, Stephen Gitu MACHATHA, Lise Lund KJEMS
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Patent number: 11786518Abstract: The present invention provides a reproxalap ophthalmic solution, and methods of using the same for treating a disease or disorder such as allergic conjunctivitis.Type: GrantFiled: March 20, 2020Date of Patent: October 17, 2023Assignee: Aldeyra Therapeutics, Inc.Inventors: David Clark, Susan Macdonald, Stephen Gitu Machatha, Lise Lund Kjems
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Patent number: 11013781Abstract: The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2, Phl p 3, Phl p 4 and/or Phl p 5, or a peptide variant thereof. Such peptides comprise at least one T cell epitope mid a high number of patients in a worldwide population will have HLA Class II alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by grass pollen species.Type: GrantFiled: July 1, 2016Date of Patent: May 25, 2021Assignees: ALK-ABELLÓ AS, LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGYInventors: Claus Lundegaard, Shashank Gupta, Bjoern Peters, Susanne Sønderkær, Jens Brimnes, Peter Adler Würtzen, Helene Henmar, Thomas Christian Mygind, Lise Lund Mærkedahl, Alessandro Sette
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Publication number: 20200323841Abstract: The present invention provides a reproxalap ophthalmic solution, and methods of using the same for treating a disease or disorder such as allergic conjunctivitis.Type: ApplicationFiled: March 20, 2020Publication date: October 15, 2020Inventors: David CLARK, Susan MACDONALD, Stephen Gitu MACHATHA, Lise Lund KJEMS
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Patent number: 10471008Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: GrantFiled: September 8, 2017Date of Patent: November 12, 2019Assignee: ALK-Abelló A/SInventors: Henrik Hugo Jacobi, Annette Rømmelmayer Lundegaard, Christian Gauguin Houghton, Jan Søndergaard-Andersen, Stig Asmul-Olsen, Lise Lund Mærkedahl
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Patent number: 10080719Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: GrantFiled: July 6, 2016Date of Patent: September 25, 2018Assignee: ALK-ABELLÓ A/SInventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen
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Publication number: 20180207228Abstract: The invention relates to combinations of peptides derived from a portion of an amino sequence of a grass pollen allergen, e.g. the allergens Phl p 1, Phl p 2, Phl p 3, Phl p 4 and/or Phl p 5, or a peptide variant thereof. Such peptides comprise at least one T cell epitope mid a high number of patients in a worldwide population will have HLA Class II alleles with the potential to bind the peptides of the peptide combinations. The invention also relates to the use of such peptide combinations in relieving an immune response caused by grass pollen species.Type: ApplicationFiled: July 1, 2016Publication date: July 26, 2018Applicants: ALK-Abelló A/SInventors: Claus Lundegaard, Shashank Gupta, Bjoern Peters, Susanne Sønderkær, Jens Brimnes, Peter Adler Würtzen, Helene Henmar, Thomas Christian Mygind, Lise Lund Mærkedahl
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Publication number: 20170367970Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: ApplicationFiled: September 8, 2017Publication date: December 28, 2017Applicant: ALK-Abelló A/SInventors: Henrik Hugo Jacobi, Annette Rømmelmayer Lundegaard, Christian Gauguin Houghton, Jan Søndergaard Andersen, Stig Asmul-Olsen, Lise Lund Mærkedahl
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Publication number: 20160324767Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: ApplicationFiled: July 6, 2016Publication date: November 10, 2016Applicants: ALK-Abello A/S, R.P. Scherer Technologies, LLCInventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
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Patent number: 9415015Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: GrantFiled: April 4, 2008Date of Patent: August 16, 2016Assignees: ALK-Abello A/S, R.P. Scherer Technologies, LLCInventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
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Patent number: 9408805Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: GrantFiled: May 27, 2014Date of Patent: August 9, 2016Assignees: ALK-Abello A/S, R.P. Scherer Technologies, LLCInventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
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Publication number: 20150126459Abstract: The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.Type: ApplicationFiled: April 16, 2013Publication date: May 7, 2015Inventors: Kaare Lund, Jens Brimnes, Helene Henmar, Hans-Henrik Ipsen, Lise Lund Mærkedahl, Gitte Nordskov Hansen, Rafael Ignacio Monsalve Clemente
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Publication number: 20140271722Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: ApplicationFiled: May 27, 2014Publication date: September 18, 2014Applicants: ALK-Abello A/S, R.P. Scherer Technologies, LLCInventors: Henrik Hugo Jacobi, Annette Roemmelmayer Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
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Patent number: 8491911Abstract: This invention relates to the use of a pharmaceutical product comprising allergen and optionally an adjuvant for fast up-dosing in connection with allergy vaccination wherein a reduced number of injections are used. The invention also relates to the pharmaceutical product as such.Type: GrantFiled: October 15, 2009Date of Patent: July 23, 2013Assignee: Alk-Abello A/SInventors: Henrik Hugo Jacobi, Eike Gunther Wüstenberg, Lise Lund Mærkedahl
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Patent number: 8329196Abstract: The invention provides allergen containing pharmaceutical products and in particular fast-dispersing solid allergen dosage forms. In particular, fast-dispersing, non-compressed solid dosage forms suitable for oromucosal administration comprising a matrix and at least one allergen are provided. Suitable matrices are gelatine, starch and mannitol. Methods for the dosage forms are also provided.Type: GrantFiled: April 4, 2008Date of Patent: December 11, 2012Assignees: ALK-Abello A/S, R.P. Scherer Technologies, LLCInventors: Henrik Hugo Jacobi, Annette R. Lundegaard, Christian Gauguin Houghton, Stig Aasmul-Olsen, Lise Lund Maerkedahl, Jan Sondergaard Andersen, Kerry Mallindine, Owen James Murray, Susan Gerrard Banbury, Desmond Yik Teng Wong, Lisa Marie Garrett, Michael Hall
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Publication number: 20110236426Abstract: This invention relates to the use of a pharmaceutical product comprising allergen and optionally an adjuvant for fast up-dosing in connection with allergy vaccination wherein a reduced number of injections are used. The invention also relates to the pharmaceutical product as such.Type: ApplicationFiled: October 15, 2009Publication date: September 29, 2011Applicant: ALK-ABELLO A/SInventors: Henrik Hugo Jacobi, Eike Gunther Wüstenberg, Lise Lund Maerkedahl
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Patent number: 7785611Abstract: Parenteral vaccine formulations and adjuvant compositions comprising certain salts as adjuvants are disclosed. Such parenteral vaccine formulations are used for generating an immune response in a subject following administration of the vaccine formulation or the adjuvant composition. Also disclosed is the use of these salts as adjuvants in parenteral vaccine formulations and adjuvant compositions, and to vaccine adjuvants comprising such salts.Type: GrantFiled: June 9, 2005Date of Patent: August 31, 2010Assignee: ALK-Abello A/SInventors: Nanna Kristensen Soni, Janne Uldal Rahbek, Stig Aasmul-Olsen, Lise Lund
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Publication number: 20090155351Abstract: The invention relates to a solid vaccine formulation adapted for mucosal administration comprising at least one antigen as active substance, wherein the formulation comprises a lyophilisate of a suspension comprising an oxygen-containing metal salt, the antigen(s) and one or more excipients selected from (i) saccharides, (ii) sugar alcohols, and (iii) amino acids or pharmaceutically acceptable salts thereof.Type: ApplicationFiled: October 4, 2006Publication date: June 18, 2009Applicant: ALK-ABELLO A/SInventors: Charlotte Hejl, Lise Lund Maerkedahl, Hans-Henrik Ipsen, Susanne Sonderkaer, Annette Rommelmayer Lundegaard, Ulla Seppala
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Publication number: 20050244420Abstract: Parenteral vaccine formulations and adjuvant compositions comprising certain salts as adjuvants are disclosed. Such parenteral vaccine formulations are used for generating an immune response in a subject following administration of the vaccine formulation or the adjuvant composition. Also disclosed is the use of these salts as adjuvants in parenteral vaccine formulations and adjuvant compositions, and to vaccine adjuvants comprising such salts.Type: ApplicationFiled: June 9, 2005Publication date: November 3, 2005Applicant: ALK-Abello A/SInventors: Nanna Soni, Janne Rahbek, Stig Aasmul-Olsen, Lise Lund
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Publication number: 20020051794Abstract: Parenteral vaccine formulations and adjuvant compositions comprising certain salts as adjuvants are disclosed. Such parenteral vaccine formulations are used for generating an immune response in a subject following administration of the vaccine formulation or the adjuvant composition. Also disclosed is the use of these salts as adjuvants in parenteral vaccine formulations and adjuvant compositions, and to vaccine adjuvants comprising such salts.Type: ApplicationFiled: August 9, 2001Publication date: May 2, 2002Applicant: ALK-ABELLO A/SInventors: Nanna Kristensen Soni, Janne Uldal Rahbek, Stig Aasmul-Olsen, Lise Lund