Abstract: The present invention provides a double-crosslinked fibrin gel, which is a solid hydrogel composed of a network structure with a blocking function and a network structure with an adhesion function, where the network structure with the blocking function is a three-dimensional fibrin network, and the network structure with the adhesion function is a three-dimensional photosensitive gel network; each channel of the photosensitive gel network has a group of the fibrin network inside, and each group of the fibrin network has overall continuity; on the whole, the three-dimensional fibrin network disperses disorderly throughout a surface and an interior of the solid hydrogel. The present invention further provides a raw material composition, a kit for preparing the double-crosslinked fibrin gel, and an application of the kit to prepare an in-situ rapid clotting and hemostatic material.

Abstract: Provided is a hemostatic composition comprising trypsin and zeolite, wherein pore channels of the zeolite are micropores, the zeolite contains divalent metal cations, and the mass ratio of the trypsin to the zeolite is 1:200-4:10. In the present invention, the trypsin specifically binds to the zeolite, allowing the trypsin to maintain a certain conformation on the surface of the zeolite and to obtain a higher procoagulant activity, thereby obtaining a hemostatic composition with an excellent blood coagulation effect. The hemostatic composition of the present invention has the advantages of a simple preparation method, low cost and convenient use, and can be widely used in hemostasis during trauma and operations, especially in emergent hemostasis in hemophilia patients.

Abstract: A material for manipulating liquid includes a porous substrate having first and second surfaces; and a wedge-shaped transport element disposed on one of the first and second surfaces, wherein the wedge-shaped transport element has a narrow end and a wide end, the wide end connected to a first reservoir, wherein the wedge-shaped transport element is configured to pass liquid from the narrow end to the wide end to the first reservoir, regardless of gravity, and wherein the first reservoir is configured to pass liquid away from the substrate in a z-direction opposite from the surface on which a liquid is deposited. The surface on which the wedge-shaped transport element is disposed is one of hydrophobic or superhydrophobic, and the wedge-shaped transport element is one of a) superhydrophilic when the first surface is hydrophobic, b) superhydrophilic when the first surface is superhydrophobic, and c) hydrophilic when the first surface is superhydrophobic.

Abstract: The present disclosure is to provide a medical material, medical protective equipment with both low cytotoxicity and high-efficiency antibacterial, antiviral properties and its manufacturing method.

Abstract: Provided is a hemostatic composition comprising trypsin and zeolite, wherein pore channels of the zeolite are micropores, the zeolite contains divalent metal cations, and the mass ratio of the trypsin to the zeolite is 1:200-4:10. In the present invention, the trypsin specifically binds to the zeolite, allowing the trypsin to maintain a certain conformation on the surface of the zeolite and to obtain a higher procoagulant activity, thereby obtaining a hemostatic composition with an excellent blood coagulation effect. The hemostatic composition of the present invention has the advantages of a simple preparation method, low cost and convenient use, and can be widely used in hemostasis during trauma and operations, especially in emergent hemostasis in hemophilia patients.

Abstract: A hemostatic compound is provided. The hemostatic compound comprises molecular sieves and a fiber. The molecular sieves are independently dispersed on a fiber surface of the fiber without agglomeration and directly contact the fiber surface. A first surface of the molecular sieve contacted with the fiber is defined as an inner surface, and a second surface of the molecular sieve uncontacted with the fiber is defined as an outer surface. The molecular sieve forms a growth-matched coupling with the fiber on the inner surface, and the growth-matched coupling refers to that a plurality of molecular sieve microparticles grow to match the fiber surface to form a tightly-coupled coupling interface that matches the fiber surface.

Abstract: Improved skin-adhesive compositions for bonding a substrate, such as an absorbent article, to skin are disclosed. More particularly, the skin-adhesive composition has an improved, yet gentle, adhesion to the skin of a user, while maintaining strong, effective bonding to various inanimate, non-skin substrates. In one embodiment, the skin-adhesive composition can provide one or more skin benefit agents to the user. The skin-adhesive composition may applied to an absorbent article, such as a panty-liner, sanitary napkin, or an incontinence article, for directly adhering the article to the skin of a user.

Abstract: The disclosure provides a hemostatic fabric containing trypsin, wherein the hemostatic fabric comprises molecular sieve/fiber composite and trypsin; molecular sieve/fiber composite comprises molecular sieves and a fiber; the molecular sieves are independently dispersed on a fiber surface of the fiber without agglomeration and directly contact the fiber surface; a surface of the molecular sieve contacted with the fiber is an inner surface, and a surface of the molecular sieve uncontacted with the fiber is an outer surface; growth-matched coupling is formed between the molecular sieves and the fiber on the inner surface of the molecular sieves; the inner surface and outer surface are composed of molecular sieve nanoparticles. In the present disclosure, trypsin is specifically combined with the molecular sieve/fiber composite, which maintains a high procoagulant activity, thereby obtaining a hemostatic fabric with excellent coagulation effect.

Abstract: The disclosure provides a molecular sieve/fiber composite material comprising molecular sieves and a fiber, the molecular sieves are distributed on the fiber surface and directly contact the fiber surface; the particle diameter D90 of the molecular sieves is 0.01 to 50 ?m, the particle size D50 of the molecular sieves is 0.005 to 25 ?m; the molecular sieves are distributed uniformly on the fiber surface of the fiber. The disclosure also provides a preparation method for the molecular sieve/fiber composite material and various applications. The molecular sieve/fiber composite material has high strength, elastic recovery ability, and dimensional stability, making the composite material strong and durable.

Abstract: A hemostatic compound is provided. The hemostatic compound comprises molecular sieves and a fiber. The molecular sieves are independently dispersed on a fiber surface of the fiber without agglomeration and directly contact the fiber surface. A first surface of the molecular sieve contacted with the fiber is defined as an inner surface, and a second surface of the molecular sieve uncontacted with the fiber is defined as an outer surface. The molecular sieve forms a growth-matched coupling with the fiber on the inner surface, and the growth-matched coupling refers to that a plurality of molecular sieve microparticles grow to match the fiber surface to form a tightly-coupled coupling interface that matches the fiber surface.

Abstract: A material for manipulating liquid volumes includes a porous substrate having first and second surfaces; and a liquid-manipulating pattern disposed on the first surface, the pattern having a first reservoir connected to a target point via a first wedge-shaped transport element to enable liquid transport from the target point to the first reservoir regardless of gravity, wherein the first surface is one of hydrophobic or superhydrophobic, and wherein the first wedge-shaped transport element is one of superhydrophilic when the first surface is hydrophobic, superhydrophilic when the first surface is superhydrophobic, and hydrophilic when the first surface is superhydrophobic. The pattern can include a second reservoir connected to the target point via a second wedge-shaped transport element to enable liquid transport from the target point to the second reservoir regardless of gravity.

Abstract: A material for manipulating liquid includes a porous substrate having first and second surfaces; and a wedge-shaped transport element disposed on one of the first and second surfaces, wherein the wedge-shaped transport element has a narrow end and a wide end, the wide end connected to a first reservoir, wherein the wedge-shaped transport element is configured to pass liquid from the narrow end to the wide end to the first reservoir, regardless of gravity, and wherein the first reservoir is configured to pass liquid away from the substrate in a z-direction opposite from the surface on which a liquid is deposited. The surface on which the wedge-shaped transport element is disposed is one of hydrophobic or superhydrophobic, and the wedge-shaped transport element is one of a) superhydrophilic when the first surface is hydrophobic, b) superhydrophilic when the first surface is superhydrophobic, and c) hydrophilic when the first surface is superhydrophobic.

Abstract: An absorbent article can include a body facing liner, a back-sheet coupled to the body facing liner, and an absorbent body. The absorbent article can also include a fluid acquisition layer. The fluid acquisition layer can include a plurality of apertures and at least one channel. The channel can include a length and a depth. The length can be defined in a horizontal plane by a distance between a proximal end and a distal end. The proximal end can be connected to a first aperture and the depth can extend from a body facing surface of the fluid acquisition layer to a garment facing surface of the fluid acquisition layer.

Abstract: An absorbent article, for example, a diaper, a training pant, a swimming pant, or a feminine care article, and so forth, includes a topsheet, which forms a body-facing surface of the absorbent article, a backsheet disposed distally from the topsheet, which forms a garment-facing surface of the absorbent article, an absorbent core positioned between the topsheet and the backsheet, and a heat-activatable expandable treatment on the garment-facing surface. The heat-activatable expandable treatment is present on the garment-facing surface in a visually distinctive shape or pattern and provides visual and/or tactile cues to a user of the absorbent article.

Abstract: In some embodiments, a nonwoven fabric includes a first web that is at least partially formed of extruded strands which include an auto-adhesive material. The nonwoven fabric is adapted to be bonded to another item that includes a similar auto-adhesive material. In other embodiments, a method of forming a nonwoven fabric includes extruding a plurality of strands that are formed of an auto-adhesive material. The method further includes routing the plurality of strands toward a moving support, depositing the plurality of strands onto the moving support, and then stabilizing the plurality of strands to form a web. In other embodiments, a fastening system includes a nonwoven fabric that has a web which is formed of a plurality of extruded strands that include an auto-adhesive material. The fastening system further includes a foam layer that has a surface with a plurality of free-standing struts that include a similar auto-adhesive material.

Abstract: Generally silicone materials adapted to releasably adhere to human skin don't attach readily to substrates such as fibrous substrates (e.g., woven and nonwoven webs), films, plastic, etc. Disclosed are inventive blends of low-tack materials, such as a low-tack silicone material, and a high-tack silicone material, such as a high-tack, hot-melt, silicone adhesive, that both releasably adhere to skin and join to various substrates, including fibrous substrates. Furthermore, these same blends may be disposed between, and attached to, a silicone adhesive layer and a substrate. In other words, the disclosed silicone blends may be used to join a silicone adhesive layer to a substrate.

Abstract: An absorbent article, for example, a diaper, a training pant, a swimming pant, or a feminine care article, and so forth, includes a topsheet, which forms a body-facing surface of the absorbent article, a backsheet disposed distally from the topsheet, which forms a garment-facing surface of the absorbent article, an absorbent core positioned between the topsheet and the backsheet, and a heat-activatable expandable treatment on the garment-facing surface. The heat-activatable expandable treatment is present on the garment-facing surface in a visually distinctive shape or pattern and provides visual and/or tactile cues to a user of the absorbent article.

Abstract: In some embodiments, a nonwoven fabric includes a first web that is at least partially formed of extruded strands which include an auto-adhesive material. The nonwoven fabric is adapted to be bonded to another item that includes a similar auto-adhesive material. In other embodiments, a method of forming a nonwoven fabric includes extruding a plurality of strands that are formed of an auto-adhesive material. The method further includes routing the plurality of strands toward a moving support, depositing the plurality of strands onto the moving support, and then stabilizing the plurality of strands to form a web. In other embodiments, a fastening system includes a nonwoven fabric that has a web which is formed of a plurality of extruded strands that include an auto-adhesive material. The fastening system further includes a foam layer that has a surface with a plurality of free-standing struts that include a similar auto-adhesive material.

Abstract: In some embodiments, a nonwoven fabric includes a first web that is at least partially formed of extruded strands which include an auto-adhesive material. The nonwoven fabric is adapted to be bonded to another item that includes a similar auto-adhesive material. In other embodiments, a method of forming a nonwoven fabric includes extruding a plurality of strands that are formed of an auto-adhesive material. The method further includes routing the plurality of strands toward a moving support, depositing the plurality of strands onto the moving support, and then stabilizing the plurality of strands to form a web. In other embodiments, a fastening system includes a nonwoven fabric that has a web which is formed of a plurality of extruded strands that include an auto-adhesive material. The fastening system further includes a foam layer that has a surface with a plurality of free-standing struts that include a similar auto-adhesive material.

Abstract: In a body adhering absorbent article, an absorbent structure is configured for disposition adjacent a female wearer's vaginal region to absorb bodily fluids discharged by the wearer. A shell supports the absorbent structure at the vaginal region and has an adhesive on a body-facing surface thereof for adhering the shell directly to the wearer. A placement aid is disposed on at least one of the absorbent structure and the shell, and is configured for sensory perception by a wearer of the article upon placement of the article on the wearer to facilitate positive alignment of the absorbent article in a target placement region of the wearer with the absorbent structure disposed adjacent the wearer's vaginal region.