Patents by Inventor Lishu ZHANG

Lishu ZHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Disubstituted and trisubstituted 1,2,3-triazoles as Wnt inhibitors
    Patent number: 10793544
    Abstract: The present disclosure provides compounds that may be useful for inhibiting Wnt pathway comprising compounds of the formula: (Ia) or (Ib) wherein the variables are as defined herein. In some aspects, the compounds may be used to inhibit the Wnt pathway and used to treat cancer, myocardial infarction, osteopetrosis, or used in the maturation of a precursor cell to a mature cell. Also provided herein in are pharmaceutical compositions of the compounds described herein.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: October 6, 2020
    Inventors: Nageswari Yarravarapu, Chuo Chen, Lawrence Lum, Lin You, Chengwei Zhang, Xiaolei Wang, Lishu Zhang
  • DISUBSTITUTED AND TRISUBSTITUTED 1,2,3-TRIAZOLES AS WNT INHIBITORS
    Publication number: 20190202804
    Abstract: The present disclosure provides compounds that may be useful for inhibiting Wnt pathway comprising compounds of the formula: (Ia) or (Ib) wherein the variables are as defined herein. In some aspects, the compounds may be used to inhibit the Wnt pathway and used to treat cancer, myocardial infarction, osteopetrosis, or used in the maturation of a precursor cell to a mature cell. Also provided herein in are pharmaceutical compositions of the compounds described herein.
    Type: Application
    Filed: August 31, 2017
    Publication date: July 4, 2019
    Inventors: Nageswari YARRAVARAPU, Chuo CHEN, Lawrence LUM, Lin YOU, Chengwei ZHANG, Xiaolei WANG, Lishu ZHANG