Abstract: In certain embodiments, the present invention provides the use of microRNA (miR)-200a to inhibit ossification and bone formation.

Abstract: The present disclosure provides compositions and methods useful for tissue engineering including a composition having chemically modified RNA (cmRNA) encapsulated in or complexed with a non-viral delivery vehicle and a biocompatible, bioresorbable scaffold and methods of using the composition to regenerate, for example, bone tissue.

Abstract: Compositions and methods to prevent, inhibit or treat aveolar or periodontal bone loss, enhance bone regeneration, prevent, inhibit or treat peri-implantitis or periodontitis, e.g., periodontitis or peri-implantitis associated with bone loss, or to prevent, inhibit or treat osteoarthritis are provided.

Abstract: The present disclosure provides a method for assessing hot coal fallout propensity of burning cigarettes based on human behavior features of ash-flicking action. The method is characterized in that the method is accomplished through an apparatus for detecting hot coal fallout propensity based on human behavior features of ash-flicking action, which include behavior features of human action of flicking cigarette ash, features of holding a cigarette, and features of force applying process and other aspects. This method can provide objective and accurate test basis for evaluation of cigarette fallout performance.

Abstract: The present disclosure provides a method for assessing hot coal fallout propensity of burning cigarettes based on human behavior features of ash-tapping action. The method is characterized in that the method is accomplished through an apparatus for detecting hot coal fallout propensity based on human behavior features of ash-tapping action, which include behavior features of human action of tapping cigarette ash, features of holding a cigarette, and features of force applying process and other aspects. This method can provide objective and accurate test basis for evaluation of cigarette fallout performance.

Abstract: A configuration management system provides a partitioned data model for collecting and representing configuration information from a diverse set of sources to allow easier modeling of very large, highly redundant sets of enterprise configuration information. The system partitions large configuration schema into logical subcomponents that can be combined, shared, and reused. The system also partitions instantiated data models into logical sub-models that can be combined, shared, reused, and incrementally updated. Each product team can provide its own configuration schema, which allows the domain experts in a particular field to provide reusable models for their products. These models may include sub-models that allow reuse of selected portions of the configuration schema. When the system stores data related to each portion of the model, it stores the data in a partitioned manner that makes incremental updates of each component of the model more straightforward and less resource intensive.

Abstract: In certain embodiments, the present invention provides the use of microRNA (miR)-200a to inhibit ossification and bone formation.

Abstract: An air negative ion generating apparatus realized by bumping against a collision surface by a high-pressure gas flow carrying water molecules includes a liquid container and a cover body snapped onto a top opening end of the liquid container, and the cover body is provided with a high-pressure gas inlet pipe; a core assembly is provided inside the cover body, and the core assembly (4) includes a liquid flow chamber, a collision component and a liquid flow inlet; and a lower port of the high-pressure gas inlet pipe faces the collision component, the liquid flow inlet is located between the lower port of the high-pressure gas inlet pipe and the collision component, the liquid flow inlet is communicated with the liquid chamber, and a lower port of the liquid flow chamber is fixedly connected with a liquid conduit extending downwards.

Abstract: The present disclosure provides compositions and methods useful for tissue engineering including a composition having chemically modified RNA (cmRNA) encapsulated in or complexed with a non-viral delivery vehicle and a biocompatible, bioresorbable scaffold and methods of using the composition to regenerate, for example, bone tissue.

Abstract: Compositions and methods to prevent, inhibit or treat aveolar or periodontal bone loss, enhance bone regeneration, prevent, inhibit or treat peri-implantitis or periodontitis, e.g., periodontitis or peri-implantitis associated with bone loss, or to prevent, inhibit or treat osteoarthritis are provided.

Abstract: In certain embodiments, the present invention provides the use of microRNA (miR)-200a and/or miR-200c to inhibit ossification and bone formation. In certain embodiments, the present invention provides the use of miR-200a inhibitor to stimulate bone regeneration.

Abstract: An air negative ion generating apparatus realized by bumping against a collision surface by a high-pressure gas flow carrying water molecules includes a liquid container and a cover body snapped onto a top opening end of the liquid container, and the cover body is provided with a high-pressure gas inlet pipe; a core assembly is provided inside the cover body, and the core assembly (4) includes a liquid flow chamber, a collision component and a liquid flow inlet; and a lower port of the high-pressure gas inlet pipe faces the collision component, the liquid flow inlet is located between the lower port of the high-pressure gas inlet pipe and the collision component, the liquid flow inlet is communicated with the liquid chamber, and a lower port of the liquid flow chamber is fixedly connected with a liquid conduit extending downwards.

Abstract: A configuration management system provides a partitioned data model for collecting and representing configuration information from a diverse set of sources to allow easier modeling of very large, highly redundant sets of enterprise configuration information. The system partitions large configuration schema into logical subcomponents that can be combined, shared, and reused. The system also partitions instantiated data models into logical sub-models that can be combined, shared, reused, and incrementally updated. Each product team can provide its own configuration schema, which allows the domain experts in a particular field to provide reusable models for their products. These models may include sub-models that allow reuse of selected portions of the configuration schema. When the system stores data related to each portion of the model, it stores the data in a partitioned manner that makes incremental updates of each component of the model more straightforward and less resource intensive.

Abstract: In certain embodiments, the present invention provides the use of microRNA (miR)-200a and/or miR-200c to inhibit ossification and bone formation. In certain embodiments, the present invention provides the use of miR-200a inhibitor to stimulate bone regeneration.

Abstract: A configuration management system provides a partitioned data model for collecting and representing configuration information from a diverse set of sources to allow easier modeling of very large, highly redundant sets of enterprise configuration information. The system partitions large configuration schema into logical subcomponents that can be combined, shared, and reused. The system also partitions instantiated data models into logical sub-models that can be combined, shared, reused, and incrementally updated. Each product team can provide its own configuration schema, which allows the domain experts in a particular field to provide reusable models for their products. These models may include sub-models that allow reuse of selected portions of the configuration schema. When the system stores data related to each portion of the model, it stores the data in a partitioned manner that makes incremental updates of each component of the model more straightforward and less resource intensive.

Abstract: A configuration management system provides a partitioned data model for collecting and representing configuration information from a diverse set of sources to allow easier modeling of very large, highly redundant sets of enterprise configuration information. The system partitions large configuration schema into logical subcomponents that can be combined, shared, and reused. The system also partitions instantiated data models into logical sub-models that can be combined, shared, reused, and incrementally updated. Each product team can provide its own configuration schema, which allows the domain experts in a particular field to provide reusable models for their products. These models may include sub-models that allow reuse of selected portions of the configuration schema. When the system stores data related to each portion of the model, it stores the data in a partitioned manner that makes incremental updates of each component of the model more straightforward and less resource intensive.

Abstract: A bioprinter and methods of using the bioprinter. The bioprinter permits selective three-dimensional movement of multiple nozzle assemblies during operation of the bioprinter. The bioprinter can be used to produce scaffold-free tissue constructs having a plurality of cellular elements interspersed among a semi-permeable vascular network. The bioprinter can also be used to print a tissue construct directly onto a tissue defect of a subject. The bioprinter can be provided as part of a bioprinting system that includes a scanner for imaging the tissue defect.

Abstract: The present disclosure provides compositions and methods useful for tissue engineering.

Abstract: A configuration management system provides a partitioned data model for collecting and representing configuration information from a diverse set of sources to allow easier modeling of very large, highly redundant sets of enterprise configuration information. The system partitions large configuration schema into logical subcomponents that can be combined, shared, and reused. The system also partitions instantiated data models into logical sub-models that can be combined, shared, reused, and incrementally updated. Each product team can provide its own configuration schema, which allows the domain experts in a particular field to provide reusable models for their products. These models may include sub-models that allow reuse of selected portions of the configuration schema. When the system stores data related to each portion of the model, it stores the data in a partitioned manner that makes incremental updates of each component of the model more straightforward and less resource intensive.

Abstract: A configuration management system provides a partitioned data model for collecting and representing configuration information from a diverse set of sources to allow easier modeling of very large, highly redundant sets of enterprise configuration information. The system partitions large configuration schema into logical subcomponents that can be combined, shared, and reused. The system also partitions instantiated data models into logical sub-models that can be combined, shared, reused, and incrementally updated. Each product team can provide its own configuration schema, which allows the domain experts in a particular field to provide reusable models for their products. These models may include sub-models that allow reuse of selected portions of the configuration schema. When the system stores data related to each portion of the model, it stores the data in a partitioned manner that makes incremental updates of each component of the model more straightforward and less resource intensive.