Patents by Inventor Liu Jiuyu

Liu Jiuyu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted urea depsipeptide analogs as activators of the ClpP endopeptidase
    Patent number: 10822377
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: September 30, 2019
    Date of Patent: November 3, 2020
    Assignee: St. Jude Children's Research Hospital
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu
  • Substituted Urea Depsipeptide Analogs as Activators of the CLPP Endopeptidase
    Publication number: 20200031872
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: September 30, 2019
    Publication date: January 30, 2020
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu
  • Substituted urea depsipeptide analogs as activators of the CLPP endopeptidase
    Patent number: 10457707
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: October 29, 2019
    Assignee: St. Jude Children's Research Hospital
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu
  • Substituted Urea Depsipeptide Analogs as Activators of the CLPP Endopeptidase
    Publication number: 20190048040
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: October 15, 2018
    Publication date: February 14, 2019
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu
  • Substituted urea depsipeptide analogs as activators of the CLPP endopeptidase
    Patent number: 10100090
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators with the ClpP endopeptidase; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of search in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: March 4, 2016
    Date of Patent: October 16, 2018
    Assignee: St. Jude Children's Research Hospital
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu
  • Substituted Urea Depsipeptide Analogs as Activators of the CLPP Endopeptidase
    Publication number: 20180079784
    Abstract: In one aspect, the invention relates to substituted urea depsipeptide analogs, derivatives thereof, and related compounds, which are useful as activators with the ClpP endopeptidease; synthesis methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating infectious disease using the compounds and compositions. This abstract is intended as a scanning tool for purposes of search in the particular art and is not intended to be limiting of the present invention.
    Type: Application
    Filed: March 4, 2016
    Publication date: March 22, 2018
    Inventors: Richard E. Lee, Ying Zhao, Liu Jiuyu