Patents by Inventor Liu Yan

Liu Yan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240287494
    Abstract: Provided are an immune cell treated by means of a magnetic field and the use thereof. A medium static magnetic field with an intensity of 0.3 T can promote the secretion of granzymes and cytokines of mouse CD8+ T cells, increase the level of ATP and mitochondrial respiration, and up-regulate the expression of mitochondrial respiratory chain related genes Uqcrb and/or Ndufs6. In addition, magnetic receptor candidate genes Isca1 and Cry1/Cry2 are involved in regulating the expression of Uqcrb and/or Ndufs6. An in-vivo experiment shows that the static magnetic field can inhibit the growth and development of tumors by means of promoting the secretion of the granzymes and cytokines of the CD8+ T cells. A killing ability test shows that the static magnetic field treatment can enhance the killing ability of the CD8+ T cells, and infusion of the CD8+ T cells treated by means of the magnetic field back into a tumor-grafted mouse has an anti-tumor effect.
    Type: Application
    Filed: April 30, 2021
    Publication date: August 29, 2024
    Inventors: XIAOYAN ZHU, Zhicai FANG, Yanwen FANG, LIU Yan, Xianxia CAO, Haifeng LIU
  • Patent number: 7919215
    Abstract: A corrosion-resistant electrode catalyst for oxygen reduction includes a main catalyst composed of at least one transition metal oxide selected from oxygen-deficient ZrO2, Ta2O5, Nb2O5, TiO2, V2O5, MoO3, and WO3 and a co-catalyst composed of gold. The electrode catalyst is used in contact with an acidic electrolyte at a potential at least 0.4 V higher than the reversible hydrogen electrode potential. The catalyst may be used, for example, in such a form that the transition metal oxide in the form of fine particles and gold in the form of fine particles, or fine particles including fine gold particles coated with the transition metal oxide are dispersed on a catalyst carrier which is an electron conductive powder. This electrode catalyst is suitable as an electrode catalyst for an electrochemical system using an acidic electrolyte in the fields of water electrolysis, inorganic/organic electrolysis, fuel cells, etc.
    Type: Grant
    Filed: August 18, 2005
    Date of Patent: April 5, 2011
    Assignee: Japan Science and Technology Agency
    Inventors: Kenichiro Ota, Nobuyuki Kamiya, Shigenori Mitsushima, Akimitsu Ishihara, Liu Yan
  • Publication number: 20070259267
    Abstract: A corrosion-resistant electrode catalyst for oxygen reduction includes a main catalyst composed of at least one transition metal oxide selected from oxygen-deficient ZrO2, Ta2O5, Nb2O5, TiO2, V2O5, MoO3, and WO3 and a co-catalyst composed of gold. The electrode catalyst is used in contact with an acidic electrolyte at a potential at least 0.4 V higher than the reversible hydrogen electrode potential. The catalyst may be used, for example, in such a form that the transition metal oxide in the form of fine particles and gold in the form of fine particles, or fine particles including fine gold particles coated with the transition metal oxide are dispersed on a catalyst carrier which is an electron conductive powder. This electrode catalyst is suitable as an electrode catalyst for an electrochemical system using an acidic electrolyte in the fields of water electrolysis, inorganic/organic electrolysis, fuel cells, etc.
    Type: Application
    Filed: August 18, 2005
    Publication date: November 8, 2007
    Applicant: JAPAN SCIENCE AND TECHNOLOGY AGENCY
    Inventors: Kenichiro Ota, Nobuyuki Kamiya, Shigenori Mitsushima, Akimitsu Ishihara, Liu Yan