Patents by Inventor Liu Ye

Liu Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260200831
    Abstract: The invention belongs to the field of biomedicine technology, and discloses a plant oil ceramide, which is obtained by reacting a plant oil fatty acid with a sphingoid base compound, wherein the sphingoid base compound is selected from sphingosine, phytosphingosine, and dihydrosphingosine, and the plant oil fatty acid is selected from olive oil fatty acid, camellia oil fatty acid, sea buckthorn oil fatty acid, grape seed oil fatty acid, nut oil fatty acid, borage oil fatty acid, rosehip oil fatty acid, soybean oil fatty acid, rice bran oil fatty acid and the like. This invention also discloses a synthesis method and use of plant oil ceramide. Said plant oil ceramide exhibits outstanding performance in skin's natural barrier repair, anti-inflammatory activity, tissue healing, anti-aging effects, and more, with broad application prospects in cosmetics, health supplements, and biopharmaceuticals.
    Type: Application
    Filed: November 23, 2023
    Publication date: July 16, 2026
    Applicant: SHENZHEN DIKEMAN BIOTECHNOLOGY CO., LTD.
    Inventors: Chaowen YANG, Liu YE, Qing LI
  • Publication number: 20260152468
    Abstract: The present disclosure belongs to the technical field of biological medicines. Disclosed is a novel ceramide which has a structure represented as formula I Further disclosed in the present disclosure are a preparation method for and the use of the ceramide. The present disclosure uses naturally-sourced and readily-available 10-hydroxycarboxylic acid as a starting raw material to construct the ceramide having a novel structure. The preparation method has a simple and convenient synthetic route and is suitable for large-scale production. Meanwhile, the obtained ceramide shows more excellent effects in the aspects of tissue repair, anti-inflammatory repair, tissue healing, moisturizing and anti-aging, and thus can be used in the fields of health care products, cosmetics and drugs.
    Type: Application
    Filed: October 10, 2023
    Publication date: June 4, 2026
    Inventors: Chaowen YANG, Liu YE
  • Publication number: 20250179007
    Abstract: The present invention provides A ceramide compound, comprising: a structure of general formula I or an enantiomer or diastereomer of general formula I: in which: R1 is selected from the condensation residues of ferulic acid, sinapic acid, abscisic acid, sotretinoin, tretinoin, fusidic acid, royal jelly acid, sorbic acid, caffeic acid or trans-cinnamic acid; R2 is selected from one of the following structures:—C15H29, —C15H31, —C15H27, —CHOHC14H27, —CHOHC14H29. The present disclosure also provides a ceramide compound containing conjugated carboxylic acid, preparation method therefor and application thereof. The invention reacts functional carboxylic acid with sphingosine base to obtain a class of ceramide compound with novel structure. The introduction of physiologically active molecular fragments of functional carboxylic acids into ceramides will enhance the original efficacy of this type of molecules and also improve the physical and chemical properties of ceramide compound.
    Type: Application
    Filed: December 1, 2023
    Publication date: June 5, 2025
    Inventors: Chaowen Yang, Liu Ye
  • Patent number: 7666650
    Abstract: The inventors have identified amylases in fungal strains of Valsaria and found that the amylase can increase the shelf life of baked products. Particularly, the novel amylase in combination with a maltogenic amylase further improves the softness of bread crumb without having detrimental effects on elasticity.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: February 23, 2010
    Assignee: NovoZymes A/S
    Inventors: Liu Ye, Tang Lan, Tina Spendler, Mary Ann Stringer