Abstract: Chromatography devices and methods for forming and using the devices are described. The devices include a polyimide-based support phase and a polymer grafted to a surface of the polyimide-based support phase. A microwave-assisted graft polymerization protocol is described to form the polymer at the surface of the support phase. Devices can be utilized in high-efficiency separation of macromolecules such as proteins.

Abstract: Separation technologies and a support/separation phases for use therein. A surface of a support phase can be modified to include a crosslinked polymer network as stationary phase to perform separation of one or more species from a liquid in highly efficient separations based on chemical interactions, i.e., chromatography. Optionally, the support phase can employ polymer fibers having channels extending axially along their surfaces. The use of the support phase to support the crosslinked stationary phase can be used in one embodiment in the process of performing micro-scale separations.