Patents by Inventor Liuxin DONG

Liuxin DONG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUNDS, PREPARATION METHOD AND MEDICAL USE THEREOF
    Publication number: 20240109890
    Abstract: Bridged heterocyclyl-substituted pyrimidine compounds, a preparation method and medical use thereof. The compounds or pharmaceutical compositions comprising same can be used as JAK1 and TYK2 kinase inhibitors for treating JAK1 and TYK2 kinase activity-related diseases such as inflammations, autoimmune diseases and cancers.
    Type: Application
    Filed: January 12, 2022
    Publication date: April 4, 2024
    Inventors: Huijun Yin, Xu Yan, Jizhou Shi, Guobiao Liu, Liuxin Dong, Mingzhao Shao
  • BRIDGED HETEROCYCLYL-SUBSTITUTED PYRIMIDINE COMPOUND, PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL USE THEREOF
    Publication number: 20220348572
    Abstract: A bridged heterocyclyl-substituted pyrimidine compound, a preparation method therefor, and pharmaceutical use thereof. In particular, the present invention relates to a compound represented by general formula (I), a preparation method for the compound, a pharmaceutical composition containing the compound, use of the compound as a JAK1 and TYK2 kinase inhibitor, and use in treating diseases related to JAK1 and TYK2 kinase activity, such as inflammations, autoimmune diseases, and cancers. The definition of each substituent in general formula (I) is the same as that in the description.
    Type: Application
    Filed: August 5, 2020
    Publication date: November 3, 2022
    Inventors: Huijun YIN, Xu YAN, Jizhou SHI, Guobiao LIU, Teng FEI, Liuxin DONG, Yuanye LIU