Patents by Inventor Liv JENSEN

Liv JENSEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • OMPG VARIANTS
    Publication number: 20240010688
    Abstract: The present disclosure provides variant OmpG polypeptides, compositions comprising the OmpG variant polypeptides, and methods for using the variant OmpG polypeptides as nanopores for determining the sequence of single stranded nucleic acids. The variant OmpG nanopores reduce the ionic current noise versus the parental OmpG polypeptide from which they are derived and thereby enable sequencing of polynucleotides with single nucleotide resolution. The reduced ionic current noise also provides for the use of these OmpG nanopore variants in other single molecule sensing applications, e.g., protein sequencing.
    Type: Application
    Filed: August 15, 2023
    Publication date: January 11, 2024
    Applicant: Roche Sequencing Solutions, Inc.
    Inventors: Cynthia CECH, Tim CRAIG, Christos TZITZILONIS, Alexander Yang, Liv JENSEN, Charlotte YANG, Corissa HARRIS, Matthew DIPIETRO, Dhruti DALAL
  • OmpG variants
    Patent number: 11767348
    Abstract: The present disclosure provides variant OmpG polypeptides, compositions comprising the OmpG variant polypeptides, and methods for using the variant OmpG polypeptides as nanopores for determining the sequence of single stranded nucleic acids. The variant OmpG nanopores reduce the ionic current noise versus the parental OmpG polypeptide from which they are derived and thereby enable sequencing of polynucleotides with single nucleotide resolution. The reduced ionic current noise also provides for the use of these OmpG nanopore variants in other single molecule sensing applications, e.g., protein sequencing.
    Type: Grant
    Filed: July 10, 2020
    Date of Patent: September 26, 2023
    Assignee: Roche Sequencing Solutions, Inc.
    Inventors: Cynthia Cech, Tim Craig, Christos Tzitzilonis, Alexander Yang, Liv Jensen, Charlotte Yang, Corissa Harris, Matthew Dipietro, Dhruti Dalal
  • OMPG VARIANTS
    Publication number: 20200392191
    Abstract: The present disclosure provides variant OmpG polypeptides, compositions comprising the OmpG variant polypeptides, and methods for using the variant OmpG polypeptides as nanopores for determining the sequence of single stranded nucleic acids. The variant OmpG nanopores reduce the ionic current noise versus the parental OmpG polypeptide from which they are derived and thereby enable sequencing of polynucleotides with single nucleotide resolution. The reduced ionic current noise also provides for the use of these OmpG nanopore variants in other single molecule sensing applications, e.g., protein sequencing.
    Type: Application
    Filed: July 10, 2020
    Publication date: December 17, 2020
    Applicant: Roche Sequencing Solutions, Inc.
    Inventors: Cynthia CECH, Tim CRAIG, Christos TZITZILONIS, Alexander YANG, Liv JENSEN, Charlotte YANG, Corissa HARRIS, Matthew DIPIETRO, Dhruti DALAL
  • OmpG variants
    Patent number: 10752658
    Abstract: The present disclosure provides variant OmpG polypeptides, compositions comprising the OmpG variant polypeptides, and methods for using the variant OmpG polypeptides as nanopores for determining the sequence of single stranded nucleic acids. The variant OmpG nanopores reduce the ionic current noise versus the parental OmpG polypeptide from which they are derived and thereby enable sequencing of polynucleotides with single nucleotide resolution. The reduced ionic current noise also provides for the use of these OmpG nanopore variants in other single molecule sensing applications, e.g., protein sequencing.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: August 25, 2020
    Assignee: ROCHE SEQUENCING SOLUTIONS, INC.
    Inventors: Cynthia Cech, Tim Craig, Christos Tzitzilonis, Alexander Yang, Liv Jensen, Charlotte Yang, Corissa Harris, Matthew DiPietro, Dhruti Dalal
  • OMPG VARIANTS
    Publication number: 20180362594
    Abstract: The present disclosure provides variant OmpG polypeptides, compositions comprising the OmpG variant polypeptides, and methods for using the variant OmpG polypeptides as nanopores for determining the sequence of single stranded nucleic acids. The variant OmpG nanopores reduce the ionic current noise versus the parental OmpG polypeptide from which they are derived and thereby enable sequencing of polynucleotides with single nucleotide resolution. The reduced ionic current noise also provides for the use of these OmpG nanopore variants in other single molecule sensing applications, e.g., protein sequencing.
    Type: Application
    Filed: September 20, 2016
    Publication date: December 20, 2018
    Applicant: GENIA TECHNOLOGIES, INC.
    Inventors: Cynthia CECH, Tim CRAIG, Christos TZITZILONIS, Alexander YANG, Liv JENSEN, Charlotte YANG, Corissa HARRIS