Patents by Inventor Liwen Zhao

Liwen Zhao has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl alkyne compound and use thereof
    Patent number: 9255107
    Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: February 9, 2016
    Assignee: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong Wang, Liwen Zhao, Di Zhang, Feng Wu, Sheng Bi, Yiping Gao, Hongbin Chen, Hongyan Chen, Cang Zhang, Yang Nan, Yang Liu
  • NOVEL NUCLEOSIDE PHOSPHORAMIDATE COMPOUND AND USE THEREOF
    Publication number: 20150361123
    Abstract: A novel nucleoside phosphoramidate compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof for the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection is provided. The pharmaceutical composition having the compound, or a stereoisomer, salt, hydrate, solvate or crystal thereof and a use of the compound or the composition in the treatment of Flaviviridae family viral infection, especially hepatitis C viral infection. The compound has a good anti-HCV effect.
    Type: Application
    Filed: March 6, 2014
    Publication date: December 17, 2015
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD
    Inventors: Yong WANG, Liwen ZHAO, Xian ZHANG, Sheng BI, Yiping GAO, Hongyan CHEN, Dezhong WANG, Yang NAN, Cang ZHANG, Yuxiu LI, Di ZHANG
  • HETEROARYL ALKYNE COMPOUND AND USE THEREOF
    Publication number: 20150299202
    Abstract: In the field of pharmaceutical chemistry compounds of general formula I having heteroaryl alkynyl moiety or pharmaceutically acceptable salts, isomers, solvates, crystals or prodrugs thereof, and pharmaceutical compositions including these compounds, as well as uses of these compounds and compositions thereof in the manufacture of a medicament. The compounds have a strong inhibitory effect on BCR-ABL tyrosine kinase and are useful for treating diseases, such as tumors.
    Type: Application
    Filed: November 27, 2013
    Publication date: October 22, 2015
    Applicant: NANJING SANHOME PHARMACEUTICAL CO., LTD.
    Inventors: Yong WANG, Liwen ZHAO, Di ZHANG, Feng WU, Sheng BI, Yiping GAO, Hongbin CHEN, Hongyan CHEN, Cang ZHANG, Yang NAN, Yang LIU
  • ALKYNYL HETEROAROMATIC COMPOUND AND USE THEREOF
    Publication number: 20150152088
    Abstract: The present invention belongs to the field of pharmaceutical chemistry, and specifically relates to compounds having an alkynyl heteroaromatic ring structure and pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates, or prodrugs thereof, and pharmaceutical compositions comprising these compounds, as well as uses of these compounds and compositions in the manufacture of a medicament. The compounds of the present invention and the pharmaceutically acceptable salts, stereoisomers, N-oxides, solvates or prodrugs thereof and the pharmaceutical compositions comprising the compounds have better anti-tumor activity.
    Type: Application
    Filed: September 12, 2013
    Publication date: June 4, 2015
    Applicant: Nanjing Sanhome Pharmaceutical Co., Ltd.
    Inventors: Yong Wang, Liwen Zhao, Wenping Zhang, Hongyan Chen, Sheng Bi, Yiping Gao, Hongbin Chen, Yang Liu, Xin Xu, Cang Zhang