Abstract: One or more aspects of the present disclosure relate to performant destaging of write pending (WP) data to disk. In embodiments, an input/output (IO) workload is received at a storage array. Additionally, the IO workload can include an IO request with a random write request. Further, a write destage context for write-pending (WP) data corresponding to the random write request can be generated by a data services engine of the storage array. In addition, using the write destage context, a disk adapter (DA), at a backend of the storage array, is enabled to destage write-pending (WP) data without reading from a target write location of the random write request on a storage device on the storage array.

Abstract: A polypeptide-coupled small molecule compound and its antiviral applications are provided. The polypeptide-coupled small molecule compound is obtained by linking a polypeptide with a sequence X?nLXGG and a small molecule compound capable of inhibiting activity of papain-like protease (PLpro) of coronavirus through a chemical bond. The polypeptide with the sequence X?nLXGG is a polypeptide with a sequence LXGG at its carboxyl terminal, X and X? are independently any amino acid, and n is an integer between 1-50. The structure of the small molecule compound capable of inhibiting the activity of PLpro contains an amino group or a hydroxyl group. The polypeptide-coupled small molecule compound can inhibit the PLpro of SARS-CoV-2 in a targeted manner, thereby inhibiting the polyprotein cleavage of coronavirus in the host, and achieving the purpose of inhibiting the replication of coronavirus in the host. It has the advantages of synergistic inhibition, low cytotoxicity and favorable solubility.

Abstract: The present disclosure provides methods, compounds and compositions that are relevant to DNA-repair and DNA-repair proteins such as tyrosyl-DNA phosphodiesterase 1 (TDP1) and type I topoisomerase (TOP1).

Abstract: The present disclosure belongs to the technical field of wastewater treatment, and discloses an electrochemical nitrogen and phosphorus removal device and a method.

Abstract: An information embedded method is used with a broadcast source and a broadcast signal receiver using a unidirectional transmission medium. The information embedded method includes steps of: storing information-push files in the broadcast signal receiver during a first time period; the broadcast source delivering broadcast signals to the broadcast signal receiver through the unidirectional transmission medium during a second time period posterior to the first time period; and the broadcast signal receiver selecting one of the information-push files according to a predetermined rule and combining the broadcast signals and information content of the selected information-push file to form an information embedded program. An information embedded system includes the broadcast source and the broadcast signal receiver.

Abstract: A signal analysis system is provided that includes master DSP circuitry, slave DSP circuitry, a LVDS bus, wherein the LVDS bus couples the master DSP circuitry to the slave DSP circuitry, and a USB interface, wherein the USB interface is coupled to the master DSP circuit.