Patents by Inventor Lixiong DAI

Lixiong DAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chiral cyclen compounds and their uses
    Patent number: 11357873
    Abstract: The present invention relates to the preparation of a series of chiral DOTA, DO3A, DO2A, DO1A, cyclen and their metal complexes, which display properties superior to those of previous DOTA-based compounds, and hence are potentially valuable as a platform for diagnostic applications. The chiral DOTAs reveal a high abundance of twisted square antiprism (TSA) geometry favoring them to be used as potential MRI contrast agents, whereas their rapid labelling properties at mild conditions make them excellent candidates for use as radiometal chelators.
    Type: Grant
    Filed: June 23, 2017
    Date of Patent: June 14, 2022
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Ga-Lai Law, Lixiong Dai
  • CHIRAL CYCLEN COMPOUNDS AND THEIR USES
    Publication number: 20210283278
    Abstract: The present invention relates to the preparation of a series of chiral DOTA, DO3A, DO2A, DO1A, cyclen and their metal complexes, which display properties superior to those of previous DOTA-based compounds, and hence are potentially valuable as a platform for diagnostic applications. The chiral DOTAs reveal a high abundance of twisted square antiprism (TSA) geometry favoring them to be used as potential MRI contrast agents, whereas their rapid labelling properties at mild conditions make them excellent candidates for use as radiometal chelators.
    Type: Application
    Filed: June 23, 2017
    Publication date: September 16, 2021
    Inventors: Ga-Lai LAW, Lixiong DAI