Patents by Inventor Liya Ding

Liya Ding has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Segmenting 3D intracellular structures in microscopy images using an iterative deep learning workflow that incorporates human contributions
    Patent number: 11501446
    Abstract: A facility for identifying the boundaries of 3-dimensional structures in 3-dimensional images is described. For each of multiple 3-dimensional images, the facility receives results of a first attempt to identify boundaries of structures in the 3-dimensional image, and causes the results of the first attempt to be presented to a person. For each of a number of 3-dimensional images, the facility receives input generated by the person providing feedback on the results of the first attempt. The facility then uses the following to train a deep-learning network to identify boundaries of 3-dimensional structures in 3-dimensional images: at least a portion of the plurality of 3-dimensional images, at least a portion of the received results, and at least a portion of provided feedback.
    Type: Grant
    Filed: October 30, 2019
    Date of Patent: November 15, 2022
    Assignee: Allen Institute
    Inventors: Jianxu Chen, Liya Ding, Matheus Palhares Viana, Susanne Marie Rafelski
  • CANCER VACCINE COMPOSITIONS AND METHODS FOR USING SAME TO TREAT CANCER
    Publication number: 20200268864
    Abstract: The present invention provides a cancer vaccine comprising DNA repair-deficient cancer cells, wherein the cancer cells are contacted with a PARP inhibitor to induce DNA breaks. In another aspect, a method of treating a subject afflicted with a cancer comprising administering to the subject a therapeutically effective amount of a cancer vaccine comprising DNA repair-deficient cancer cells, wherein the cancer cells are contacted with a PARP inhibitor to induce DNA breaks, is provided. The present invention also provides a kit comprising DNA repair-deficient cancer cells modified as described herein, PARP inhibitors, immune checkpoint inhibitors, and combinations thereof, packaged in a suitable container.
    Type: Application
    Filed: October 24, 2018
    Publication date: August 27, 2020
    Inventors: Jean Zhao, Liya Ding, Qiwei Wang, Hye-Jung Kim
  • SEGMENTING 3D INTRACELLULAR STRUCTURES IN MICROSCOPY IMAGES USING AN ITERATIVE DEEP LEARNING WORKFLOW THAT INCORPORATES HUMAN CONTRIBUTIONS
    Publication number: 20200134831
    Abstract: A facility for identifying the boundaries of 3-dimensional structures in 3-dimensional images is described. For each of multiple 3-dimensional images, the facility receives results of a first attempt to identify boundaries of structures in the 3-dimensional image, and causes the results of the first attempt to be presented to a person. For each of a number of 3-dimensional images, the facility receives input generated by the person providing feedback on the results of the first attempt. The facility then uses the following to train a deep-learning network to identify boundaries of 3-dimensional structures in 3-dimensional images: at least a portion of the plurality of 3-dimensional images, at least a portion of the received results, and at least a portion of provided feedback.
    Type: Application
    Filed: October 30, 2019
    Publication date: April 30, 2020
    Inventors: Jianxu Chen, Liya Ding, Matheus Palhares Viana, Susanne Marie Rafelski