Patents by Inventor Lizbeth Cornivelli

Lizbeth Cornivelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • IPSC-DERIVED CELL COMPOSITIONS, AND RELATED SYSTEMS AND METHODS FOR CARTILAGE REPAIR
    Publication number: 20210038651
    Abstract: Presented herein are personalized compositions comprising iPSCs and/or iPSC-derived cells (cells) and methods of producing personalized compositions suitable for various therapies, including chondrogenesis therapies, to be administered to an individual or a group of individuals. The cells and/or cell lines, and any compositions derived therefrom, are identified as compatible with a specific individual or specific group of individuals using an identification of a cell type indicative of compatibility such as an HLA match. The compatible cells are then used to derive “personalized” compositions, wherein the “personalized” compositions comprise one or more cell-secreted molecules suitable for therapy. It is found herein that a composition comprising one or more iPSC-derived MSCs, iPSC-derived chondrocytes, and iPSC-derived chondrons may provide improved treatment efficacy than would be offered by bone marrow-MSCs (BM-MSCs) or compositions comprising BM-MSCs.
    Type: Application
    Filed: March 5, 2019
    Publication date: February 11, 2021
    Inventors: Robin Y. Smith, Marcie A. Glicksman, Lizbeth Cornivelli
  • DIAGNOSIS AND TREATMENT OF AUTOANTIBODY-MEDIATED HEART DISEASE
    Publication number: 20150247851
    Abstract: Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 antibodies to cardiac autoantigens.
    Type: Application
    Filed: May 14, 2015
    Publication date: September 3, 2015
    Inventors: MYRA A. LIPES, LIZBETH CORNIVELLI
  • DIAGNOSIS OF MYOCARDIAL AUTOIMMUNITY IN HEART DISEASE
    Publication number: 20140255956
    Abstract: Provided herein are, inter alia, methods of diagnosing myocardial autoimmunity in subjects by detecting the presence of autoantibodies to cardiac antigens in the subjects.
    Type: Application
    Filed: May 27, 2014
    Publication date: September 11, 2014
    Inventors: Myra A. Lipes, Lizbeth Cornivelli, Venkata Siva Rama Krishnam Raju Gottumukkala
  • DIAGNOSIS AND TREATMENT OF AUTOANTIBODY-MEDIATED HEART DISEASE
    Publication number: 20140112912
    Abstract: Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 antibodies to cardiac autoantigens.
    Type: Application
    Filed: March 12, 2013
    Publication date: April 24, 2014
    Inventors: Myra A. Lipes, Lizbeth Cornivelli
  • DIAGNOSIS AND TREATMENT OF AUTOANTIBODY-MEDIATED HEART DISEASE
    Publication number: 20130202589
    Abstract: Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 antibodies to cardiac autoantigens.
    Type: Application
    Filed: March 12, 2013
    Publication date: August 8, 2013
    Inventors: Myra A. Lipes, Lizbeth Cornivelli
  • Diagnosis of Myocardial Autoimmunity in Heart Disease
    Publication number: 20130121998
    Abstract: Provided herein are, inter alia, methods of diagnosing myocardial autoimmunity in subjects by detecting the presence of autoantibodies to cardiac antigens in the subjects.
    Type: Application
    Filed: June 10, 2011
    Publication date: May 16, 2013
    Inventors: Myra A. Lipes, Lizbeth Cornivelli, Venkata Siva Rama Krishnam Raju Gottumukkala
  • Diagnosis and treatment of cardiac troponin 1 (cTn1) autoantibody-mediated heart disease
    Patent number: 8420330
    Abstract: Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 autoantibodies to cardiac troponin I (cTnI).
    Type: Grant
    Filed: July 15, 2011
    Date of Patent: April 16, 2013
    Inventors: Myra A. Lipes, Lizbeth Cornivelli
  • Diagnosis and Treatment of Autoantibody-Mediated Heart Disease
    Publication number: 20130017192
    Abstract: Provided herein are, inter alia, methods of diagnosing and treating autoimmune cardiomyopathy in subjects, based upon the detection of IgG4 autoantibodies to cardiac troponin I (cTnI).
    Type: Application
    Filed: July 15, 2011
    Publication date: January 17, 2013
    Inventors: Myra A. Lipes, Lizbeth Cornivelli