Patents by Inventor Ljudmila F. Kozyreva

Ljudmila F. Kozyreva has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for preparing strains which produce aminoacids
    Patent number: 4278765
    Abstract: A method for constructing strains which produce aminoacids comprising combining of a DNA chromosome fragment of a donor microorganism containing genes controlling the synthesis of a selected aminoacid and having a mutation destroying the negative regulation of the synthesis of this aminoacid with a vector DNA molecule to form a hybrid DNA molecule. Use is made of a vector DNA molecule capable of providing amplification of the hybrid DNA molecule. The resulting hybrid DNA molecule is used for transforming cells of the recipient strain having the mutation blocking the synthesis of the selected aminoacid in this strain and the mutation partly blocking the related step of metabolism of this aminoacid to yield the strain capable of increased productivity of the selected aminoacid.
    Type: Grant
    Filed: June 28, 1979
    Date of Patent: July 14, 1981
    Inventors: Vladimir G. Debabov, Jury I. Kozlov, Nelli I. Zhdanova, Evgeny M. Khurges, Nikolai K. Yankovsky, Mikhail N. Rozinov, Rustem S. Shakulov, Boris A. Rebentish, Vitaly A. Livshits, Mikhail M. Gusyatiner, Sergei V. Mashko, Vera N. Moshentseva, Ljudmila F. Kozyreva, Raisa A. Arsatiants
  • Method of producing L-isoleucine using Brevibacterium flavum
    Patent number: 4237228
    Abstract: A method of producing L-isoleucine which comprises culturing the strain of Brevibacterium flavum VNII Genetika 10-89 deposited under the number CMIM B-1507 in a nutrient medium containing sources of nitrogen, carbon, mineral salts and vitamins and under aerobic conditions.Said strain makes it possible to produce L-isoleucine with a yield of 17 g/l and more.
    Type: Grant
    Filed: June 22, 1978
    Date of Patent: December 2, 1980
    Inventors: Nelli I. Zhdanova, Tatyana V. Leonova, Ljudmila F. Kozyreva