Patents by Inventor Lloyd B. Jeffs

Lloyd B. Jeffs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NON-LIPOSOMAL SYSTEMS FOR NUCLEIC ACID DELIVERY
    Publication number: 20130303587
    Abstract: The present invention provides novel, stable lipid particles having a non-lamellar structure and comprising one or more active agents or therapeutic agents, methods of making such lipid particles, and methods of delivering and/or administering such lipid particles. More particularly, the present invention provides stable nucleic acid-lipid particles (SNALP) that have a non-lamellar structure and that comprise a nucleic acid (such as one or more interfering RNA), methods of making the SNALP, and methods of delivering and/or administering the SNALP.
    Type: Application
    Filed: June 30, 2011
    Publication date: November 14, 2013
    Applicant: Protiva Biotherapeutics, Inc.
    Inventors: Ed Yaworski, Lloyd B. Jeffs, Lorne R. Palmer
  • siRNA SILENCING OF APOLIPOPROTEIN B
    Publication number: 20110189300
    Abstract: The present invention provides nucleic acid-lipid particles comprising siRNA molecules that silence ApoB expression and methods of using such nucleic acid-lipid particles to silence ApoB expression.
    Type: Application
    Filed: May 20, 2010
    Publication date: August 4, 2011
    Applicant: Protiva Biotherapeutics, Inc.
    Inventors: Ian MacLachlan, Lloyd B. Jeffs, Adam Judge, Amy C.H. Lee, Lorne R. Palmer, Vandana Sood
  • siRNA silencing of genes expressed in cancer
    Publication number: 20090149403
    Abstract: The present invention provides nucleic acid-lipid particles comprising siRNA molecules that silence genes expressed in cancer (e.g., Eg5, EGFR or XIAP) and methods of using such nucleic acid-lipid particles to silence Eg5, EGFR or XIAP gene expression.
    Type: Application
    Filed: May 29, 2007
    Publication date: June 11, 2009
    Applicant: Protiva Biotherapeutics, Inc.
    Inventors: Ian MacLachlan, Adam Judge, Vandana Sood, James Heyes, Lloyd B. Jeffs, Lorne Palmer