Patents by Inventor Lloyd C. Franklin

Lloyd C. Franklin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GABA and L-glutamic acid analogs for antiseizure treatment
    Patent number: 5608090
    Abstract: A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: March 4, 1997
    Assignees: Northwestern University, Warner-Lambert Company
    Inventors: Richard B. Silverman, Ryszard Andruszkiewicz, Po-Wai Yuen, Denis M. Sobieray, Lloyd C. Franklin, Mark A. Schwindt
  • GABA and L-glutamic acid analogs for antiseizure treatment
    Patent number: 5599973
    Abstract: A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: February 4, 1997
    Assignees: Northwestern University, Warner-Lambert Company
    Inventors: Richard B. Silverman, Ryszard Andruszkiewicz, Po-Wai Yuen, Denis M. Sobieray, Lloyd C. Franklin, Mark A. Schwindt
  • GABA and L-glutamic acid analogs for antiseizure treatment
    Patent number: 5563175
    Abstract: A compound of the formula ##STR1## wherein R.sub.1 is a straight or branched alkyl group having from 1 to 6 carbon atoms, phenyl, or cycloalkyl having from 3 to 6 carbon atoms; R.sub.2 is hydrogen or methyl; and R.sub.3 is hydrogen, methyl or carboxyl; which is useful in the treatment of seizure disorders. Processes are disclosed for the preparation of the compound. Intermediates prepared during the synthesis of the compound are also disclosed.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: October 8, 1996
    Assignees: Northwestern University, Warner-Lambert Company
    Inventors: Richard B. Silverman, Ryszard Andruszkiewicz, Po-Wai Yuen, Denis M. Sobieray, Lloyd C. Franklin, Mark A. Schwindt
  • Process for preparing methylolated hydantoins
    Patent number: 4908456
    Abstract: A method for making methylolated hydantoins by reacting a hydantoin, a formaldehyde such as paraformaldehyde and an alkaline catalyst at conditions of temperature and pressure sufficient to induce reaction to obtain a product in essentially 100% active form. Dry methylolated hydantoin product made by this process may be stored or shipped more economically than an aqueous solution containing a methylolated hydantoin.
    Type: Grant
    Filed: April 5, 1989
    Date of Patent: March 13, 1990
    Assignees: Takatori Corporation, Takatori Hitech Co., Ltd.
    Inventors: Thomas E. Farina, Lloyd C. Franklin
  • Method for preparing halogenated hydantoins
    Patent number: 4654424
    Abstract: A halogenated hydantoin product and method of producing same for use as e.g. a bleaching agent or disinfectant comprising a halogenated hydantoin of the formula ##STR1## wherein R is methyl or ethyl and X.sub.1 and X.sub.2 which may be the same or different are chlorine or bromine, either as the sole constituent or in admixture with halogenated dimethylhydantoins. The products are substantially dust-free, free-flowing and upon compaction form a solid product of high physical integrity.
    Type: Grant
    Filed: September 20, 1985
    Date of Patent: March 31, 1987
    Assignee: Glyco Inc.
    Inventors: Theodore A. Girard, Lloyd C. Franklin
  • Shaped halogenated hydantoins
    Patent number: 4560766
    Abstract: A halogenated hydantoin product and method of producing same for use as e.g. a bleaching agent or disinfectant comprising a halogenated hydantoin of the formula ##STR1## wherein R is methyl or ethyl and X.sub.1 and X.sub.2 which may be the same or different is chlorine or bromine, either as the sole constituent or in admixture with halogenated dimethylhydantoins. The products are substantially dust-free, free-flowing and upon compaction form a solid product of high physical integrity.
    Type: Grant
    Filed: February 9, 1983
    Date of Patent: December 24, 1985
    Assignee: Glyco Chemicals, Inc.
    Inventors: Theodore A. Girard, Lloyd C. Franklin
  • Process for the interconversion of crystalline forms of ethylene bis-stearamide
    Patent number: 4248792
    Abstract: A process for preparing alpha and beta crystalline forms of N,N'-ethylene bis-stearamide (EBS). Heating of EBS at temperatures of 120.degree.-160.degree. C. to melt the EBS results in formation of 95+% alpha which when cooled to 40.degree. C. or less remains in the alpha state, but upon reheating to about 80.degree. C. results in 95+% conversion to the beta crystalline form. Heating of the alpha crystalline form at temperatures ranging from about 45.degree.-90.degree. C. for selected periods of time results in mixtures of alpha and beta.
    Type: Grant
    Filed: June 22, 1979
    Date of Patent: February 3, 1981
    Assignee: Glyco Chemicals, Inc.
    Inventors: Marvin Rosen, Lloyd C. Franklin