Patents by Inventor Lloyd Gordon Bentley

Lloyd Gordon Bentley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NORMALIZATION CONTROLS FOR MANAGING LOW SAMPLE INPUTS IN NEXT GENERATION SEQUENCING
    Publication number: 20220002781
    Abstract: The disclosure provides compositions and methods for the quantification of a target nucleic acid sequence or sequences in a sample using next generation sequencing. The methods of the disclosure can be used to determine titer of one or more target organisms in a sample.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 6, 2022
    Inventors: Eric HARNESS, Vaishnavi NAGESH, Lloyd Gordon BENTLEY, Meredith L. CARPENTER
  • Determination of KIR haplotypes associated with disease
    Patent number: 9914970
    Abstract: Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual.
    Type: Grant
    Filed: February 3, 2015
    Date of Patent: March 13, 2018
    Assignees: Roche Molecular Systems, Inc., Conexio Genomics Pty Ltd, Children's Hospital & Research Center at Oakland
    Inventors: Martha Ladner, Elizabeth Trachtenberg, Lloyd Gordon Bentley, Damian Goodridge, Henry A. Erlich
  • Determination of KIR Haplotypes Associated with Disease
    Publication number: 20150184243
    Abstract: Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual.
    Type: Application
    Filed: February 3, 2015
    Publication date: July 2, 2015
    Applicants: Roche Molecular Systems, Inc., Children's Hospital Oakland Research Institute
    Inventors: Martha Ladner, Elizabeth Trachtenberg, Lloyd Gordon Bentley, Damian Goodridge, Henry A. Erlich
  • Determination of KIR haplotypes associated with disease
    Patent number: 9005894
    Abstract: Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: April 14, 2015
    Assignees: Roche Molecular Systems, Inc., Childrens Hospital & Research Center at Oakland, Conexio Genomics Pty Ltd
    Inventors: Martha Ladner, Elizabeth Trachtenberg, Lloyd Gordon Bentley, Damian Goodridge, Henry A. Erlich
  • DETERMINATION OF KIR HAPLOTYPES ASSOCIATED WITH DISEASE
    Publication number: 20110129830
    Abstract: Disclosed is a method of determining KIR genotypes for one or more individuals in parallel, the method comprising: for each individual, amplifying the polymorphic exon sequences of the KIR genes, pooling the KIR amplicons, performing emulsion PCR followed by pyrosequencing in parallel to determine all the amplicon sequences present in the individual to determine which KIR alleles are present in the individual.
    Type: Application
    Filed: September 17, 2010
    Publication date: June 2, 2011
    Applicant: ROCHE MOLECULAR SYSTEMS, INC.
    Inventors: Martha Ladner, Elizabeth Trachtenberg, Lloyd Gordon Bentley, Damian Goodridge, Henry A. Erlich