Patents by Inventor Lloyd J. Simons

Lloyd J. Simons has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SYNTHETIC TRITERPENOIDS WITH NITROGEN-BASED SUBSTITUENTS AT C-17 AND METHODS OF USE THEREOF
    Publication number: 20230111914
    Abstract: In some aspects, the present disclosure provides compounds of the formula: (I) and (II), wherein the variables are defined herein. Also provided are pharmaceutical compositions thereof. In some aspects, the compounds and compositions provided herein may be used as antioxidant inflammation modulators. In some aspects, the present disclosure provides methods wherein the compounds and composition described herein are used for the treatment of diseases and disorders associated with inflammation and cancer.
    Type: Application
    Filed: December 18, 2020
    Publication date: April 13, 2023
    Inventors: Christopher F. BENDER, Ha DO, Xin JIANG, Haizhou SUN, Melean VISNICK, Ingo JANSER, Lloyd J. SIMONS, Heinrich J. SCHOSTAREZ
  • ANTIBACTERIAL FLUOROQUINOLONE ANALOGS
    Publication number: 20120058989
    Abstract: Compounds having antibacterial activity are disclosed. The compounds have the following structure (I): including stereoisomers, pharmaceutically acceptable salts and prodrugs thereof, wherein A, B, D, E, G, R1, R2, R3, R4, R5, R6 and R7 are as defined herein. Methods associated with preparation and use of such compounds, as well as pharmaceutical compositions comprising such compounds, are also disclosed.
    Type: Application
    Filed: April 7, 2011
    Publication date: March 8, 2012
    Applicant: Achaogen, Inc.
    Inventors: Allan S. Wagman, Heinz E. Moser, Glenn A. McEnroe, James B. Aggen, Martin S. Linsell, Adam A. Goldblum, John H. Griffin, Lloyd J. Simons, Thomas R. Belliotti, Christina R. Harris, Toni-Jo Poel, Michael J. Melnick, Ricky D. Gaston
  • Piperidine Derivatives
    Publication number: 20100120858
    Abstract: The invention relates to compounds of Formula (I) and pharmaceutically acceptable acid addition salts thereof, wherein *, X1, X2, R5A, R5B, R6, R7, and R8 are as defined in the specification; pharmaceutical compositions; therapeutic combinations; and methods of treating diseases and disorders.
    Type: Application
    Filed: August 13, 2007
    Publication date: May 13, 2010
    Inventors: Bradley W. Caprathe, Rocco D. Gogliotti, Rex A. Jennings, Lloyd J. Simons