Patents by Inventor Lo CHANG
Lo CHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 12208104Abstract: The present disclosure relates to pharmaceutical composition for the treatment of joint pain. The composition contains a lipid mixture comprising one or more phospholipids; and an effective amount of a therapeutic agent or a pharmaceutically acceptable salt thereof, where the total amount of phospholipids in said composition is about 20 mM to about 150 mM, optionally 70 mM to 110 mM. Also provided is the use of the pharmaceutical composition in the treatment of joint pain by articular injection.Type: GrantFiled: September 16, 2019Date of Patent: January 28, 2025Assignees: Taiwan Liposome Co., Ltd., TLC Biopharmaceuticals, Inc.Inventors: Yun-Long Tseng, Sheue-Fang Shih, Po-Chun Chang, Lo Chang
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Patent number: 11932756Abstract: The present invention relates to a modified polyvinyl butyral (PVB) material, comprising a PVB composite material, a first filler, an anti-hydrolysis agent, zinc stearate, calcium stearate, a polymeric dispersant, a deodorant, tetramethylthiuram monosulfide, and trimethylolpropane tris(3-mercaptopropionate); wherein the PVB composite material is obtained by plasticizing a composition comprising PVB and a first plasticizer. The present invention also relates to a preparation method of the modified PVB material, and a modified PVB product comprising a modified PVB layer prepared from a material comprising the modified PVB material.Type: GrantFiled: April 12, 2022Date of Patent: March 19, 2024Assignee: LEADER SHINING MATERIAL CO., LTD.Inventor: Chi-Lo Chang
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Publication number: 20230323106Abstract: The present invention relates to a modified polyvinyl butyral (PVB) material, comprising a PVB composite material, a first filler, an anti-hydrolysis agent, zinc stearate, calcium stearate, a polymeric dispersant, a deodorant, tetramethylthiuram monosulfide, and trimethylolpropane tris(3-mercaptopropionate); wherein the PVB composite material is obtained by plasticizing a composition comprising PVB and a first plasticizer. The present invention also relates to a preparation method of the modified PVB material, and a modified PVB product comprising a modified PVB layer prepared from a material comprising the modified PVB material.Type: ApplicationFiled: April 12, 2022Publication date: October 12, 2023Inventor: CHI-LO CHANG
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Publication number: 20210338688Abstract: The present disclosure relates to pharmaceutical composition for the treatment of joint pain. The composition contains a lipid mixture comprising one or more phospholipids; and an effective amount of a therapeutic agent or a pharmaceutically acceptable salt thereof, where the total amount of phospholipids in said composition is about 20 mM to about 150 mM, optionally 70 mM to 110 mM. Also provided is the use of the pharmaceutical composition in the treatment of joint pain by articular injection.Type: ApplicationFiled: September 16, 2019Publication date: November 4, 2021Inventors: Yun-Long TSENG, Sheue-Fang SHIH, Po-Chun CHANG, Lo CHANG
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Publication number: 20160354781Abstract: The invention provides a microfluidic plate for various biological experiments and analyses. The microfluidic plate of the invention comprises one or more unit formed on or in the plate, wherein the unit comprises (a) a chamber; (b) a fluid channel adjacent to the chamber; (c) at least one microfluidic gap region connected between the chamber and the channel and in fluidic communication therewith; and (d) at least one opening located at the channel and connected with the gaps and in fluidic communication with the gaps.Type: ApplicationFiled: April 12, 2016Publication date: December 8, 2016Inventors: Andrew Man Chung Wo, Lo-Chang Hsiung, Wei-Yuan Ma
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Publication number: 20120074108Abstract: Disclosed is a micro-hole structure and a method for forming the micro-hole. A working energy source is projected onto a predetermined drilling site on a first surface of a substrate for a given period of time so as to melt a portion of the substrate to form a working energy entering section until the working energy source penetrates through a second surface of the substrate to form a micro-hole. A melt formed by melting a portion of the substrate in the micro-hole next to the second surface is allowed to reflow in a direction opposite to the projection of the working energy source to thereby form a reflow section in the substrate. Further, a two or more stages emission of laser pulses is used to form the micro-hole to control the bore diameter of the micro-hole.Type: ApplicationFiled: December 6, 2011Publication date: March 29, 2012Applicant: NATIONAL TAIWAN UNIVERSITYInventors: ANDREW M. WO, DE-SHIEN JONG, CHANG-YU CHEN, KUAN-TING LIU, LO-CHANG HSIUNG
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Patent number: 7919048Abstract: A cellular microarray is disclosed, which has a substrate, multiple first conductive lines, multiple second conductive lines, and multiple PIREs arranged on the surface of the substrate in an array. Each PIRE includes multiple first ring-shaped electrodes, and multiple second ring-shaped electrodes. The first ring-shaped electrodes, and the second ring-shaped electrodes are located on the surface of the substrate alternately in each PIRE. Moreover, the outermost ring-shaped electrodes of any two adjacent feather-shaped electrodes are different. The disclosed cellular microarray can adhere the cells rapidly and uniformly, increase the output of manufacturing, and reduce the cost for manufacturing and application.Type: GrantFiled: April 25, 2008Date of Patent: April 5, 2011Assignee: National Taiwan UniversityInventors: Andrew M. Wo, Lo-Chang Hsiung, Chun-Hui Yang, Hsin-Yu Lee
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Publication number: 20100062214Abstract: Disclosed is a micro-hole structure and a method for forming the micro-hole. A working energy source is projected onto a predetermined drilling site on a first surface of a substrate for a given period of time so as to melt a portion of the substrate to form a working energy entering section until the working energy source penetrates through a second surface of the substrate to form a micro-hole. A melt formed by melting a portion of the substrate in the micro-hole next to the second surface is allowed to reflow in a direction opposite to the projection of the working energy source to thereby form a reflow section in the substrate. Further, a two or more stages emission of laser pulses is used to form the micro-hole to control the bore diameter of the micro-hole.Type: ApplicationFiled: September 5, 2008Publication date: March 11, 2010Inventors: Andrew M. Wo, De-Shien Jong, Chang-Yu Chen, Kuan-Ting Liu, Lo-Chang Hsiung
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Publication number: 20090093376Abstract: A cellular microarray is disclosed, which has a substrate, multiple first conductive lines, multiple second conductive lines, and multiple PIREs arranged on the surface of the substrate in an array. Each PIRE includes multiple first ring-shaped electrodes, and multiple second ring-shaped electrodes. The first ring-shaped electrodes, and the second ring-shaped electrodes are located on the surface of the substrate alternately in each PIRE. Moreover, the outermost ring-shaped electrodes of any two adjacent feather-shaped electrodes are different. The disclosed cellular microarray can adhere the cells rapidly and uniformly, increase the output of manufacturing, and reduce the cost for manufacturing and application.Type: ApplicationFiled: April 25, 2008Publication date: April 9, 2009Applicant: National Taiwan UniversityInventors: Andrew M. Wo, Lo-Chang Hsiung, Chun-Hui Yang, Hsin-Yu Lee
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Patent number: 6991007Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.Type: GrantFiled: March 4, 2005Date of Patent: January 31, 2006Inventor: Chi-Lo Chang
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Patent number: 6978813Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.Type: GrantFiled: March 4, 2005Date of Patent: December 27, 2005Inventor: Chi-Lo Chang
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Patent number: 6929042Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner, so as to cut the mortises and tenons in the workpiece.Type: GrantFiled: July 30, 2003Date of Patent: August 16, 2005Inventor: Chi-Lo Chang
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Publication number: 20050145298Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.Type: ApplicationFiled: March 4, 2005Publication date: July 7, 2005Inventor: Chi-Lo Chang
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Publication number: 20050145299Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.Type: ApplicationFiled: March 4, 2005Publication date: July 7, 2005Inventor: Chi-Lo Chang
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Publication number: 20050145297Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.Type: ApplicationFiled: March 4, 2005Publication date: July 7, 2005Inventor: Chi-Lo Chang
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Publication number: 20050022899Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner, so as to cut the mortises and tenons in the workpiece.Type: ApplicationFiled: July 30, 2003Publication date: February 3, 2005Inventor: Chi-Lo Chang
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Publication number: 20040206865Abstract: A position confining device of a dovetail machin has a panel, a pair of locking blocks, and a plurality of fastening bolts. The panel has at least two through holes. Each locking block has a locking plate, a protruded ring disposed on the locking plate, an inner post disposed on the locking plate and surrounded by the protruded ring, and a groove defined by the inner post and the protruded ring. Each protruded ring is inserted in the corresponding through hole of the panel. Each fastening bolt fastens the corresponding locking plate and the panel.Type: ApplicationFiled: August 12, 2003Publication date: October 21, 2004Inventor: Chi-Lo Chang
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Patent number: 6751039Abstract: A method of controlling bias supply sources for magneto-resistive transducer (MR) heads to provide essentially the same predetermined lifetime for the MR heads, by determining dependence of head lifetime on bias supply level and on head stripe temperature, and setting a bias supply level for each head based on said dependence of lifetime on bias supply level and on head temperature, to provide essentially the same predetermined lifetime for the heads.Type: GrantFiled: November 3, 2001Date of Patent: June 15, 2004Assignee: Maxtor CorporationInventors: Nelson Shih-Cheng Cheng, Caleb Kai-Lo Chang, Steven Lambert, Tue Thanh Ngo
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Patent number: 6424505Abstract: A method and system for protecting a suspension assembly, such as a flex-on-suspension or trace suspension assembly, is disclosed. The suspension assembly is for use with a magnetoresistive (MR) head including an MR sensor. The MR sensor has a first end and a second end. The method and system include providing a first lead coupled with the first end of the MR sensor and providing a second lead coupled with the second end of the MR sensor. The method and system further include providing an insulating film supporting a first portion of the first lead and a second portion of the second lead. The method and system also include providing a resistor coupled with the first lead, the resistor being sufficiently large to damp a transient current in the MR sensor.Type: GrantFiled: May 6, 1999Date of Patent: July 23, 2002Assignee: Read-Rite CorporationInventors: Chung F. Lam, Caleb Kai-lo Chang, Dino Tommy Anthony Martinez
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Patent number: 6373660Abstract: A method and system for protecting a magnetoresistive (MR) head from electrostatic discharge damage is disclosed. The MR head includes an MR sensor having a first end and a second end. The MR head is coupled with a suspension assembly including a first lead coupled with the first end of the MR sensor, a second lead coupled with the second end of the MR sensor, and an insulating film supporting first and second portions of the first and second leads. In one aspect, the method and system include providing first and second test pads coupled with the first and second leads, respectively. The first and second test pads are for testing the MR head. The method and system also include providing a permanent resistor coupled to the first and second test pads. The permanent resistor has a resistance of less than approximately ten thousand ohms. In another aspect, the suspension assembly includes first and second head gimbal assembly pads coupled to the first and second leads, respectively.Type: GrantFiled: March 14, 2000Date of Patent: April 16, 2002Assignee: Read-Rite CorporationInventors: Chung Fai Lam, Caleb Kai-lo Chang, Dino Tommy Anthony Martinez, Dallas W. Meyer, Seila Chao Chim