Patents by Inventor Lo CHANG

Lo CHANG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12208104
    Abstract: The present disclosure relates to pharmaceutical composition for the treatment of joint pain. The composition contains a lipid mixture comprising one or more phospholipids; and an effective amount of a therapeutic agent or a pharmaceutically acceptable salt thereof, where the total amount of phospholipids in said composition is about 20 mM to about 150 mM, optionally 70 mM to 110 mM. Also provided is the use of the pharmaceutical composition in the treatment of joint pain by articular injection.
    Type: Grant
    Filed: September 16, 2019
    Date of Patent: January 28, 2025
    Assignees: Taiwan Liposome Co., Ltd., TLC Biopharmaceuticals, Inc.
    Inventors: Yun-Long Tseng, Sheue-Fang Shih, Po-Chun Chang, Lo Chang
  • Patent number: 11932756
    Abstract: The present invention relates to a modified polyvinyl butyral (PVB) material, comprising a PVB composite material, a first filler, an anti-hydrolysis agent, zinc stearate, calcium stearate, a polymeric dispersant, a deodorant, tetramethylthiuram monosulfide, and trimethylolpropane tris(3-mercaptopropionate); wherein the PVB composite material is obtained by plasticizing a composition comprising PVB and a first plasticizer. The present invention also relates to a preparation method of the modified PVB material, and a modified PVB product comprising a modified PVB layer prepared from a material comprising the modified PVB material.
    Type: Grant
    Filed: April 12, 2022
    Date of Patent: March 19, 2024
    Assignee: LEADER SHINING MATERIAL CO., LTD.
    Inventor: Chi-Lo Chang
  • Publication number: 20230323106
    Abstract: The present invention relates to a modified polyvinyl butyral (PVB) material, comprising a PVB composite material, a first filler, an anti-hydrolysis agent, zinc stearate, calcium stearate, a polymeric dispersant, a deodorant, tetramethylthiuram monosulfide, and trimethylolpropane tris(3-mercaptopropionate); wherein the PVB composite material is obtained by plasticizing a composition comprising PVB and a first plasticizer. The present invention also relates to a preparation method of the modified PVB material, and a modified PVB product comprising a modified PVB layer prepared from a material comprising the modified PVB material.
    Type: Application
    Filed: April 12, 2022
    Publication date: October 12, 2023
    Inventor: CHI-LO CHANG
  • Publication number: 20210338688
    Abstract: The present disclosure relates to pharmaceutical composition for the treatment of joint pain. The composition contains a lipid mixture comprising one or more phospholipids; and an effective amount of a therapeutic agent or a pharmaceutically acceptable salt thereof, where the total amount of phospholipids in said composition is about 20 mM to about 150 mM, optionally 70 mM to 110 mM. Also provided is the use of the pharmaceutical composition in the treatment of joint pain by articular injection.
    Type: Application
    Filed: September 16, 2019
    Publication date: November 4, 2021
    Inventors: Yun-Long TSENG, Sheue-Fang SHIH, Po-Chun CHANG, Lo CHANG
  • Publication number: 20160354781
    Abstract: The invention provides a microfluidic plate for various biological experiments and analyses. The microfluidic plate of the invention comprises one or more unit formed on or in the plate, wherein the unit comprises (a) a chamber; (b) a fluid channel adjacent to the chamber; (c) at least one microfluidic gap region connected between the chamber and the channel and in fluidic communication therewith; and (d) at least one opening located at the channel and connected with the gaps and in fluidic communication with the gaps.
    Type: Application
    Filed: April 12, 2016
    Publication date: December 8, 2016
    Inventors: Andrew Man Chung Wo, Lo-Chang Hsiung, Wei-Yuan Ma
  • Publication number: 20120074108
    Abstract: Disclosed is a micro-hole structure and a method for forming the micro-hole. A working energy source is projected onto a predetermined drilling site on a first surface of a substrate for a given period of time so as to melt a portion of the substrate to form a working energy entering section until the working energy source penetrates through a second surface of the substrate to form a micro-hole. A melt formed by melting a portion of the substrate in the micro-hole next to the second surface is allowed to reflow in a direction opposite to the projection of the working energy source to thereby form a reflow section in the substrate. Further, a two or more stages emission of laser pulses is used to form the micro-hole to control the bore diameter of the micro-hole.
    Type: Application
    Filed: December 6, 2011
    Publication date: March 29, 2012
    Applicant: NATIONAL TAIWAN UNIVERSITY
    Inventors: ANDREW M. WO, DE-SHIEN JONG, CHANG-YU CHEN, KUAN-TING LIU, LO-CHANG HSIUNG
  • Patent number: 7919048
    Abstract: A cellular microarray is disclosed, which has a substrate, multiple first conductive lines, multiple second conductive lines, and multiple PIREs arranged on the surface of the substrate in an array. Each PIRE includes multiple first ring-shaped electrodes, and multiple second ring-shaped electrodes. The first ring-shaped electrodes, and the second ring-shaped electrodes are located on the surface of the substrate alternately in each PIRE. Moreover, the outermost ring-shaped electrodes of any two adjacent feather-shaped electrodes are different. The disclosed cellular microarray can adhere the cells rapidly and uniformly, increase the output of manufacturing, and reduce the cost for manufacturing and application.
    Type: Grant
    Filed: April 25, 2008
    Date of Patent: April 5, 2011
    Assignee: National Taiwan University
    Inventors: Andrew M. Wo, Lo-Chang Hsiung, Chun-Hui Yang, Hsin-Yu Lee
  • Publication number: 20100062214
    Abstract: Disclosed is a micro-hole structure and a method for forming the micro-hole. A working energy source is projected onto a predetermined drilling site on a first surface of a substrate for a given period of time so as to melt a portion of the substrate to form a working energy entering section until the working energy source penetrates through a second surface of the substrate to form a micro-hole. A melt formed by melting a portion of the substrate in the micro-hole next to the second surface is allowed to reflow in a direction opposite to the projection of the working energy source to thereby form a reflow section in the substrate. Further, a two or more stages emission of laser pulses is used to form the micro-hole to control the bore diameter of the micro-hole.
    Type: Application
    Filed: September 5, 2008
    Publication date: March 11, 2010
    Inventors: Andrew M. Wo, De-Shien Jong, Chang-Yu Chen, Kuan-Ting Liu, Lo-Chang Hsiung
  • Publication number: 20090093376
    Abstract: A cellular microarray is disclosed, which has a substrate, multiple first conductive lines, multiple second conductive lines, and multiple PIREs arranged on the surface of the substrate in an array. Each PIRE includes multiple first ring-shaped electrodes, and multiple second ring-shaped electrodes. The first ring-shaped electrodes, and the second ring-shaped electrodes are located on the surface of the substrate alternately in each PIRE. Moreover, the outermost ring-shaped electrodes of any two adjacent feather-shaped electrodes are different. The disclosed cellular microarray can adhere the cells rapidly and uniformly, increase the output of manufacturing, and reduce the cost for manufacturing and application.
    Type: Application
    Filed: April 25, 2008
    Publication date: April 9, 2009
    Applicant: National Taiwan University
    Inventors: Andrew M. Wo, Lo-Chang Hsiung, Chun-Hui Yang, Hsin-Yu Lee
  • Patent number: 6991007
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: January 31, 2006
    Inventor: Chi-Lo Chang
  • Patent number: 6978813
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: December 27, 2005
    Inventor: Chi-Lo Chang
  • Patent number: 6929042
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner, so as to cut the mortises and tenons in the workpiece.
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: August 16, 2005
    Inventor: Chi-Lo Chang
  • Publication number: 20050145298
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.
    Type: Application
    Filed: March 4, 2005
    Publication date: July 7, 2005
    Inventor: Chi-Lo Chang
  • Publication number: 20050145299
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.
    Type: Application
    Filed: March 4, 2005
    Publication date: July 7, 2005
    Inventor: Chi-Lo Chang
  • Publication number: 20050145297
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner so as to cut the mortises and tenons in the workpiece.
    Type: Application
    Filed: March 4, 2005
    Publication date: July 7, 2005
    Inventor: Chi-Lo Chang
  • Publication number: 20050022899
    Abstract: A semi-automatic mortising machine includes a support base, a support bar, a guide device, a working device, a distance adjusting device, and a dust collection box. Thus, the displacement direction can be controlled in a manual manner during the working process, and the cutting operation is performed in an automatic manner, so as to cut the mortises and tenons in the workpiece.
    Type: Application
    Filed: July 30, 2003
    Publication date: February 3, 2005
    Inventor: Chi-Lo Chang
  • Publication number: 20040206865
    Abstract: A position confining device of a dovetail machin has a panel, a pair of locking blocks, and a plurality of fastening bolts. The panel has at least two through holes. Each locking block has a locking plate, a protruded ring disposed on the locking plate, an inner post disposed on the locking plate and surrounded by the protruded ring, and a groove defined by the inner post and the protruded ring. Each protruded ring is inserted in the corresponding through hole of the panel. Each fastening bolt fastens the corresponding locking plate and the panel.
    Type: Application
    Filed: August 12, 2003
    Publication date: October 21, 2004
    Inventor: Chi-Lo Chang
  • Patent number: 6751039
    Abstract: A method of controlling bias supply sources for magneto-resistive transducer (MR) heads to provide essentially the same predetermined lifetime for the MR heads, by determining dependence of head lifetime on bias supply level and on head stripe temperature, and setting a bias supply level for each head based on said dependence of lifetime on bias supply level and on head temperature, to provide essentially the same predetermined lifetime for the heads.
    Type: Grant
    Filed: November 3, 2001
    Date of Patent: June 15, 2004
    Assignee: Maxtor Corporation
    Inventors: Nelson Shih-Cheng Cheng, Caleb Kai-Lo Chang, Steven Lambert, Tue Thanh Ngo
  • Patent number: 6424505
    Abstract: A method and system for protecting a suspension assembly, such as a flex-on-suspension or trace suspension assembly, is disclosed. The suspension assembly is for use with a magnetoresistive (MR) head including an MR sensor. The MR sensor has a first end and a second end. The method and system include providing a first lead coupled with the first end of the MR sensor and providing a second lead coupled with the second end of the MR sensor. The method and system further include providing an insulating film supporting a first portion of the first lead and a second portion of the second lead. The method and system also include providing a resistor coupled with the first lead, the resistor being sufficiently large to damp a transient current in the MR sensor.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: July 23, 2002
    Assignee: Read-Rite Corporation
    Inventors: Chung F. Lam, Caleb Kai-lo Chang, Dino Tommy Anthony Martinez
  • Patent number: 6373660
    Abstract: A method and system for protecting a magnetoresistive (MR) head from electrostatic discharge damage is disclosed. The MR head includes an MR sensor having a first end and a second end. The MR head is coupled with a suspension assembly including a first lead coupled with the first end of the MR sensor, a second lead coupled with the second end of the MR sensor, and an insulating film supporting first and second portions of the first and second leads. In one aspect, the method and system include providing first and second test pads coupled with the first and second leads, respectively. The first and second test pads are for testing the MR head. The method and system also include providing a permanent resistor coupled to the first and second test pads. The permanent resistor has a resistance of less than approximately ten thousand ohms. In another aspect, the suspension assembly includes first and second head gimbal assembly pads coupled to the first and second leads, respectively.
    Type: Grant
    Filed: March 14, 2000
    Date of Patent: April 16, 2002
    Assignee: Read-Rite Corporation
    Inventors: Chung Fai Lam, Caleb Kai-lo Chang, Dino Tommy Anthony Martinez, Dallas W. Meyer, Seila Chao Chim