Patents by Inventor Lodewijk Julius Anton TOONEN

Lodewijk Julius Anton TOONEN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOSITIONS AND METHODS FOR MODULATING ATAXIN 3 EXPRESSION
    Publication number: 20230040829
    Abstract: Disclosed are methods for modulating splicing of Ataxin 3 mRNA in an animal with modified oligonucleotides. Such compounds and methods are useful to treat, prevent, or ameliorate spinocerebellar ataxia type 3 (SCA3) in an individual in need thereof.
    Type: Application
    Filed: February 23, 2022
    Publication date: February 9, 2023
    Inventors: Frank RIGO, Thazha P. PRAKASH, Wilhelmina Maria Clasina VAN ROON-MOM, Lodewijk Julius Anton TOONEN
  • Compositions and methods for modulating Ataxin 3 expression
    Patent number: 11293025
    Abstract: Disclosed are methods for modulating splicing of Ataxin 3 mRNA in an animal with modified oligonucleotides. Such compounds and methods are useful to treat, prevent, or ameliorate spinocerebellar ataxia type 3 (SCA3) in an individual in need thereof.
    Type: Grant
    Filed: November 26, 2019
    Date of Patent: April 5, 2022
    Assignees: Ionis Pharmaceuticals, Inc., Academisch Ziekenhuis Leiden
    Inventors: Frank Rigo, Thazha P. Prakash, Wilhelmina Maria Clasina Van Roon-Mom, Lodewijk Julius Anton Toonen
  • COMPOSITIONS AND METHODS FOR MODULATING ATAXIN 3 EXPRESSION
    Publication number: 20200325473
    Abstract: Disclosed are methods for modulating splicing of Ataxin 3 mRNA in an animal with modified oligonucleotides. Such compounds and methods are useful to treat, prevent, or ameliorate spinocerebellar ataxia type 3 (SCA3) in an individual in need thereof.
    Type: Application
    Filed: November 26, 2019
    Publication date: October 15, 2020
    Inventors: Frank RIGO, Thazha P. PRAKASH, Wilhelmina Maria Clasina VAN ROON-MOM, Lodewijk Julius Anton TOONEN
  • Compositions and methods for modulating Ataxin 3 expression
    Patent number: 10533175
    Abstract: Disclosed are methods for modulating splicing of Ataxin 3 mRNA in an animal with modified oligonucleotides. Such compounds and methods are useful to treat, prevent, or ameliorate spinocerebellar ataxia type 3 (SCA3) in an individual in need thereof.
    Type: Grant
    Filed: September 23, 2016
    Date of Patent: January 14, 2020
    Assignees: Ionis Pharmaceuticals, Inc., Academisch Ziekenhuis Leiden
    Inventors: Frank Rigo, Thazha P. Prakash, Wilhelmina Maria Clasina Van Roon-Mom, Lodewijk Julius Anton Toonen
  • COMPOSITIONS AND METHODS FOR MODULATING ATAXIN 3 EXPRESSION
    Publication number: 20180258425
    Abstract: Disclosed are methods for modulating splicing of Ataxin 3 mRNA in an animal with modified oligonucleotides. Such compounds and methods are useful to treat, prevent, or ameliorate spinocerebellar ataxia type 3 (SCA3) in an individual in need thereof.
    Type: Application
    Filed: September 23, 2016
    Publication date: September 13, 2018
    Inventors: Frank RIGO, Thazha P. PRAKASH, Wilhelmina Maria Clasina VAN ROON-MOM, Lodewijk Julius Anton TOONEN