Abstract: A closure assembly for a medical container having a sleeve with a tip cap disposed therein in an accessible position relative to an access opening. A cover is fixedly secured to one end of said sleeve, opposite to said access opening and a retainer is fixedly secured within the sleeve, adjacent the cover and in a removably retaining engagement with the tip cap. The removably retaining engagement includes the retainer having one or more segments disposed in retaining engagement with an exterior of the tip cap. Upon detachment of the tip cap from the retainer and the removal thereof from the sleeve, the one or more segments are separable from one another and/or a remainder of the retainer, while being maintained in a captured position within the sleeve.