Patents by Inventor Lohray Vidya Bhushan

Lohray Vidya Bhushan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for preparing diltiazem
    Patent number: 6180785
    Abstract: A process for preparing a 2R-hydroxy-3-[(2-amino-phenylthio)]-3-[(p-alkoxyaryl)] propanoic acid alkyl ester of formula (V) wherein R is an alkyl, or benzoyl residue, R1 is hydrogen, an alkyl, alkoxy, aryloxy, phenyl, naphthyl, or hydroxy residue, and R2 and R3 are independently of each other hydrogen, and alkyl, alkoxy, alkylamino, alkylthio, aryl, or halogen residue, which comprises refluxing 2-aminothiophenol, or 2-aminothionaphthol with a compound of Formula (IV) that is 5S-(p-alkoxyphenyl)-4R-carboalkoxy-1,3,2-dioxathiolane-2-oxide when X is S, or the corresponding cyclic carbonate, in the presence of an organic solvent and an inert atmosphere, and recovering the resultant compound of Formula (V).
    Type: Grant
    Filed: January 28, 1999
    Date of Patent: January 30, 2001
    Inventors: Lohray Braj Bhushan, Balakrishnan Ezhuthachan Jayachandran, Lohray Vidya Bhushan, Ravindranathan Thottappillil
  • Process for preparing diltiazem
    Patent number: 5869697
    Abstract: A compound of formula (IV) ##STR1## wherein R.sup.1 is hydrogen, an alkyl, alkoxy, alkylamino, alkylthio, aryl, aryloxy, or halogen residue; R is an alkyl, or aryl residue, and X is S or C, which is a valuable intermediate for producing Diltiazem.
    Type: Grant
    Filed: July 7, 1997
    Date of Patent: February 9, 1999
    Assignee: Council of Scientific & Industrial Research
    Inventors: Lohray Braj Bhushan, Balakrishnan Ezhuthachan Jayachandran, Lohray Vidya Bhushan, Ravindranathan Thottappillil