Abstract: The present invention generally relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogues and mimetics thereof, as neuroprotective agents for the treatment and or prevention of cognitive impairment and neurological disorders including but not limited to cerebral ischemia or cerebral infarction, status epilepticus, perinatal asphyxia, anoxia, and cerebral trauma, as well as to the treatment and prevention of chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Dementia with Lewy Bodies. The present invention also generally provides manufacturing methods to prepare dosage forms. The present invention further generally relates to the use of cyclic Prolyl Glycine and analogues and mimetics thereof, as neuroprotective and neuro-regenerating agents for the treatment and or prevention of depression and other psychological disorders.

Abstract: The present invention recognizes that there is a need for the prophylaxis or treatment of COVID and COVID-19. A first aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using various pharmaceutical compositions. A second aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using combinations of antimalarial drugs and antiviral drugs. A third aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using nanoparticle formulations that include pharmaceutical compositions. A fourth aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using combinations of various pharmaceutical compositions. A fifth aspect of the present invention generally relates to methods of prophylaxis or treatment of COVID or COVID-19 using a polio vaccine and pharmaceutical compositions.

Abstract: A caliper-arm-position sensor comprising a differential variable reluctance transducer (DVRT) and circuits to drive the DVRT with a substantially sinusoidal signal and to sample a signal at the DVRT once per drive-signal cycle at a predetermined position in the drive-signal cycle is disclosed.

Abstract: The present invention generally relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogues and mimetics thereof, as neuroprotective agents for the treatment and or prevention of cognitive impairment and neurological disorders including but not limited to cerebral ischemia or cerebral infarction, status epilepticus, perinatal asphyxia, anoxia, and cerebral trauma, as well as to the treatment and prevention of chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Dementia with Lewy Bodies. The present invention also generally provides manufacturing methods to prepare of dosage forms. The present invention further generally relates to the use of cyclic Prolyl Glycine and analogues and mimetics thereof, as neuroprotective and neuro-regenerating agents for the treatment and or prevention of depression and other psychological disorders.

Abstract: The present invention generally relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogues and mimetics thereof, as neuroprotective agents for the treatment and or prevention of cognitive impairment and neurological disorders including but not limited to cerebral ischemic or cerebral infarction, status epilepticus, perinatal asphyxia, anoxia, and cerebral trauma, as well as to the treatment and prevention of chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, and as anticonvulsants. The present invention also generally provides manufacturing methods to prepare of dosage forms. The present invention further generally relates to the use of cyclic Prolyl Glycine and analogues and mimetics thereof, as neuroprotective and neuro-regenerating agents for the treatment and or prevention of depression and other psychological disorders.

Abstract: A caliper-arm-position sensor comprising a differential variable reluctance transducer (DVRT) and circuits to drive the DVRT with a substantially sinusoidal signal and to sample a signal at the DVRT once per drive-signal cycle at a predetermined position in the drive-signal cycle is disclosed.

Abstract: The present invention generally relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogues and mimetics thereof, as neuroprotective agents for the treatment and or prevention of cognitive impairment and neurological disorders including but not limited to cerebral ischemic or cerebral infarction, status epilepticus, perinatal asphyxia, anoxia, and cerebral trauma, as well as to the treatment and prevention of chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, and as anticonvulsants. The present invention also generally provides manufacturing methods to prepare of dosage forms. The present invention further generally relates to the use of cyclic Prolyl Glycine and analogues and mimetics thereof, as neuroprotective and neuro-regenerating agents for the treatment and or prevention of depression and other psychological disorders.

Abstract: The invention relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogs and mimetics thereof, as neuroprotective agents for the treatment and or prevention of neurological disorders including but not limited to cerebral ischemia or cerebral infarction resulting from a range of phenomena, such as thromboembolic or hemorrhagic stroke, cerebral basospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia such as from drowning, pulmonary surgery, and cerebral trauma, as well as to the treatment and prevention of chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, and as anticonvulsants.

Abstract: An integrated circuit radio transceiver and method therefor includes circuitry and logic for transmitting outgoing or ingoing communication signals as well as one of a digital data signal or a digital clock on the same antenna signal paths between a radio and a switch fabric. The switch fabric is operable to selectively couple any of a plurality of antennas to antenna signal paths based upon the digital data and the digital clock extracted from at least one of the antenna signal paths conducting RF signals. The switch fabric is further operable to extract all required power from at least one antenna signal path that may be used to conduct RF.

Abstract: An integrated circuit radio transceiver and method therefor includes circuitry and logic for transmitting outgoing or ingoing communication signals as well as one of a digital data signal or a digital clock on the same antenna signal paths between a radio and a switch fabric. The switch fabric is operable to selectively couple any of a plurality of antennas to antenna signal paths based upon the digital data and the digital clock extracted from at least one of the antenna signal paths conducting RF signals. The switch fabric is further operable to extract all required power from at least one antenna signal path that may be used to conduct RF.

Abstract: The invention relates to the use of cyclic Prolyl Glycine (“cyclic PG” or “cPG”) and analogs and mimetics thereof, as neuroprotective agents for the treatment and or prevention of neurological disorders including but not limited to cerebral ischemia or cerebral infarction resulting from a range of phenomena, such as thromboembolic or hemorrhagic stroke, cerebral basospasms, hypoglycemia, cardiac arrest, status epilepticus, perinatal asphyxia, anoxia such as from drowning, pulmonary surgery, and cerebral trauma, as well as to the treatment and prevention of chronic neurodegenerative disorders such as Alzheimer's disease, Parkinson's disease, and Huntington's disease, and as anticonvulsants.

Abstract: A tool is provided for assistance in removing tires from wheel rims. The tool has a body with a lateral opening for engaging the flange of a wheel rim, preferably opening into a cavity that is wider than the opening such that the tools pivots between stable positions on a fulcrum at which lips of the lateral opening bear against the flange. A roller is mounted on one end of the tool body to exert a downward pressure on the tire sidewall, and a handle protrudes on an end opposite the cavity and fulcrum from the roller. The roller displaces the tire bead from its seat against the rim when removing or installing the bead of a tire that is already at least partly on the rim, or supports the second bead of a tire whose first bead is axially outside of the rim relative to the wheel rotation axis.

Abstract: A floor cleaning machine has one or more barriers immediately behind one or more scrubbing brushes, wherein the barriers capture and control flow of a cleaning solution (and/or other substances) that exits from beneath the scrubbing brush(es) so that such a solution is retained adjacent the scrub brush(es) and recycled underneath the scrub brush(es) for enhancing the floor cleaning effectiveness of the floor cleaning machine. The captured solution is urged back into contact with the scrubbing brush(es) by the same rotating action that urged the solution to be ejected from the scrubbing brush(es). The machine also includes at least one splash guard and a squeegee mounted at the rear of the machine, with each of these latter components serving distinctly different functions from that of the barriers. The machine may also include an exterior top storage area for retaining various items that are useful in cleaning the floor.

Abstract: The present invention relates generally to a floor treatment component that is designed such that as it passes over an uneven surface it applies a substantially constant downward force to the uneven surface. Specifically, systems for connecting the floor treatment component to a floor treatment apparatus are described.

Abstract: The present invention relates generally to an apparatus for cleaning or otherwise treating a floored surface that includes a platform adapted to support the weight of an operator. In addition, one embodiment of the present invention is capable of generally performing 360° turns to facilitate the treatment of difficult to access portions of the floored surface.

Abstract: A floor care machine that includes a deck having a motor, a rotatable floor care element for engaging a floor surface, and a handle apparatus pivotally mounted to the deck is provided. Additionally, there are first and second sets of wheels toward the rear of the deck and on opposite sides of handle apparatus pivot attachment points. In addition to the attachment points, the handle apparatus and the deck are coupled together by a rigid handle link which is pivotally attached to the deck at one end and pivotally attached to the handle apparatus at the other end. The handle link communicates deck pivot forces between the deck and the handle apparatus, and in particular, communicates such forces resulting from a compressing or decompressing of a compressible component provided along the length of the handle apparatus.

Abstract: A floor cleaning machine has one or more barriers immediately behind one or more scrubbing brushes, wherein the barriers capture and control flow of a cleaning solution (and/or other substances) that exits from beneath the scrubbing brush(es) so that such a solution is retained adjacent the scrub brush(es) and recycled underneath the scrub brush(es) for enhancing the floor cleaning effectiveness of the floor cleaning machine. The captured solution is urged back into contact with the scrubbing brush(es) by the same rotating action that urged the solution to be ejected from the scrubbing brush(es). The machine also includes at least one splash guard and a squeegee mounted at the rear of the machine, with each of these latter components serving distinctly different functions from that of the barriers. The machine may also include an exterior top storage area for retaining various items that are useful in cleaning the floor.

Abstract: A temperature sensing apparatus is disclosed which generates a signal having a frequency which is related to temperature. The apparatus includes means for receiving a temperature input, an output for carrying an output signal having a frequency related to the temperature output, and a converting means for converting the temperature input to the output signal.