Patents by Inventor Loic Le Hir de Fallois
Loic Le Hir de Fallois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Long-acting injectable formulations comprising an isoxazoline active agent, methods and uses thereof
Patent number: 11484528Abstract: This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.Type: GrantFiled: September 30, 2019Date of Patent: November 1, 2022Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Susan Mancini Cady, Peter Cheifetz, Izabela Galeska, Loic Le Hir de Fallois -
Patent number: 11382949Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) wherein the stereochemical configuration of at least one carbon atom bearing the groups Cy1, Cy2, R1, R2, R3, R4, Ra and Rb is inverted compared with the naturally occurring cyclic depsipeptide PF1022A. The invention also provides compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: GrantFiled: November 15, 2017Date of Patent: July 12, 2022Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Publication number: 20220098241Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.Type: ApplicationFiled: December 8, 2021Publication date: March 31, 2022Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Patent number: 11230571Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.Type: GrantFiled: April 23, 2019Date of Patent: January 25, 2022Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Publication number: 20200354408Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: ApplicationFiled: July 30, 2020Publication date: November 12, 2020Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Meng, Hyoung Ik Lee, Cyprian O. Ogbu
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Patent number: 10793604Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: GrantFiled: August 23, 2018Date of Patent: October 6, 2020Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Meng, Hyoung Ik Lee, Cyprian O. Ogbu
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Long-acting injectable formulations comprising an isoxazoline active agent, methods and uses thereof
Patent number: 10561641Abstract: This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.Type: GrantFiled: February 26, 2016Date of Patent: February 18, 2020Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Susan Mancini Cady, Peter Cheifetz, Izabela Galeska, Loic Le Hir de Fallois -
LONG-ACTING INJECTABLE FORMULATIONS COMPRISING AN ISOXAZOLINE ACTIVE AGENT, METHODS AND USES THEREOF
Publication number: 20200022959Abstract: This invention relates to long-acting injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a poloxamer, and a co-solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the long-acting injectable formulations of the invention to the animal in need thereof.Type: ApplicationFiled: September 30, 2019Publication date: January 23, 2020Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Susan Mancini Cady, Peter Cheifetz, Izabela Galeska, Loic Le Hir de Fallois -
Publication number: 20190307838Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) wherein the stereochemical configuration of at least one carbon atom bearing the groups Cy1, Cy2, R1, R2, R3, R4, Ra and Rb is inverted compared with the naturally occurring cyclic depsipeptide PF1022A. The invention also provides compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: ApplicationFiled: November 15, 2017Publication date: October 10, 2019Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Publication number: 20190248840Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.Type: ApplicationFiled: April 23, 2019Publication date: August 15, 2019Applicant: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Patent number: 10344056Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.Type: GrantFiled: December 14, 2016Date of Patent: July 9, 2019Assignee: BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Patent number: 10251863Abstract: The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one indole derivative active agent. The invention also provides for an improved method for eradicating and controlling liver fluke parasite infections and infestations in a mammal comprising administering the compositions of the invention to the mammal in need thereof.Type: GrantFiled: June 26, 2017Date of Patent: April 9, 2019Assignee: MERIAL INC.Inventors: Charles Meng, Loïc Le Hir de Fallois
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Publication number: 20180362589Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: ApplicationFiled: August 23, 2018Publication date: December 20, 2018Applicant: MERIAL INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Meng, Hyoung Ik Lee, Cyprian O. Ogbu
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Patent number: 10081656Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: GrantFiled: May 20, 2016Date of Patent: September 25, 2018Assignee: MERIAL, INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Meng, Hyoung Ik Lee, Cyprian O. Ogbu
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Publication number: 20170290803Abstract: The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one indole derivative active agent. The invention also provides for an improved method for eradicating and controlling liver fluke parasite infections and infestations in a mammal comprising administering the compositions of the invention to the mammal in need thereof.Type: ApplicationFiled: June 26, 2017Publication date: October 12, 2017Applicant: MERIAL, INC.Inventors: Charles Meng, Loïc Le Hir de Fallois
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Patent number: 9776986Abstract: The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one indole derivative active agent. The invention also provides for an improved method for eradicating and controlling liver fluke parasite infections and infestations in a mammal comprising administering the compositions of the invention to the mammal in need thereof.Type: GrantFiled: June 19, 2015Date of Patent: October 3, 2017Assignee: MERIAL INC.Inventors: Charles Meng, Loïc Le Hir de Fallois
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Publication number: 20170233438Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals, including humans. The compounds and compositions may be used for combating parasites in or on animals including mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in animals, including birds and mammals.Type: ApplicationFiled: December 14, 2016Publication date: August 17, 2017Applicant: MERIAL INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Q. Meng, Hyoung Ik Lee
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Publication number: 20170020848Abstract: This invention relates to extended release injectable formulations for combating parasites in animals, comprising at least one isoxazoline active agent, a pharmaceutically acceptable polymer, and a solvent. This invention also provides for improved methods for eradicating, controlling, and preventing parasite infections and infestations in an animal comprising administering the extended release injectable formulations of the invention to the animal in need thereof.Type: ApplicationFiled: April 6, 2016Publication date: January 26, 2017Applicant: MERIAL INC.Inventors: Susan Mancini Cady, Peter Cheifetz, Izabela Galeska, Loic Le Hir de Fallois
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Publication number: 20170022253Abstract: The present invention provides cyclic depsipeptide compounds of formula (I) and compositions comprising the compounds that are effective against parasites that harm animals. The compounds and compositions may be used for combating parasites in or on mammals and birds. The invention also provides for an improved method for eradicating, controlling and preventing parasite infestation in birds and mammals.Type: ApplicationFiled: May 20, 2016Publication date: January 26, 2017Applicant: MERIAL INC.Inventors: Loic Le Hir de Fallois, Greg Pacofsky, Alan Long, Charles Meng, Hyoung Ik Lee, Cyprian O. Ogbu
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Publication number: 20150366198Abstract: The invention relates to oral, topical or injectable compositions for combating liver fluke parasites in mammals, comprising at least one indole derivative active agent. The invention also provides for an improved method for eradicating and controlling liver fluke parasite infections and infestations in a mammal comprising administering the compositions of the invention to the mammal in need thereof.Type: ApplicationFiled: June 19, 2015Publication date: December 24, 2015Applicant: MERIAL, INC.Inventors: Charles Meng, Loïc Le Hir de Fallois