Patents by Inventor Loic Patrick Le Hir de Fallois

Loic Patrick Le Hir de Fallois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20150073153
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Application
    Filed: November 17, 2014
    Publication date: March 12, 2015
    Applicant: Merial Limited
    Inventors: Charles Q. Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • Patent number: 8937185
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: January 20, 2015
    Assignee: Merial Limited
    Inventors: Charles Q Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • Patent number: 8921408
    Abstract: This invention relates to compositions for combating parasites in animals, comprising 1-arylpyrazole compounds alone or in combination with formamidine compounds. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infestation in an animal comprising administering the compositions of the invention to the animal in need thereof.
    Type: Grant
    Filed: May 23, 2013
    Date of Patent: December 30, 2014
    Assignee: Merial Limited
    Inventors: Mark David Soll, Luiz Gustavo Cramer, Patrice Wurtz, James Pate, Natalya Shub, Loic Patrick Le Hir de Fallois, Philip Reid Timmons
  • Publication number: 20140315794
    Abstract: The present invention relates to novel dihydroazole of formula (I) and salts thereof: Wherein R1, A1, A2, G, X and Y are as defined in the description, compositions thereof, processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
    Type: Application
    Filed: November 21, 2013
    Publication date: October 23, 2014
    Applicant: MERIAL LIMITED
    Inventors: Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Douglas Edward Wilkinson, Brent Christopher Beck
  • Patent number: 8822689
    Abstract: The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Grant
    Filed: September 19, 2012
    Date of Patent: September 2, 2014
    Assignees: Merial Limited, Aventis Agriculture
    Inventors: Loic Patrick Le Hir de Fallois, Scot Kevin Huber, Hyoung Ik Lee, Robert Toms Jacobs
  • Publication number: 20140228785
    Abstract: This invention relates to compositions for combating parasites in animals, comprising 1-arylpyrazole compounds alone or in combination with formamidine compounds. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infestation in an animal comprising administering the compositions of the invention to the animal in need thereof.
    Type: Application
    Filed: February 12, 2013
    Publication date: August 14, 2014
    Applicant: MERIAL LIMITED
    Inventors: Mark David Soll, Luiz Gustavo Cramer, Patrice Wurtz, James Pate, Natalya Shub, Loic Patrick Le Hir de Fallois, Philip Reid Timmons
  • Patent number: 8785372
    Abstract: Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R1 is hydrogen, cyano, halogen, R8, formyl, —C(O)R8, —C(O)OR8, —C(O)NR9R10, or —C(S)NH2; R2 is R8 or —S(O)mR11; R3 is methyl, ethyl or C1-C4 haloalkyl; R4, R5 and R7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R12, —S(O)nR12 or SF5; Z is a nitrogen atom or C—R13; R8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R9 is hydrogen, alkyl, haloalkyl or alkoxy; R10 is hydrogen, alkyl, haloalkyl or alkoxy; R11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R12 is alkyl or haloalkyl; R13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.
    Type: Grant
    Filed: May 15, 2013
    Date of Patent: July 22, 2014
    Assignee: Aventis Agriculture
    Inventors: Hyoung Ik Lee, Loic Patrick Le Hir de Fallois, Philip Reid Timmons, William Glenn Cawthorne, Adalberto Perez de Leon
  • Publication number: 20140080862
    Abstract: The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Application
    Filed: September 19, 2012
    Publication date: March 20, 2014
    Applicants: AVENTIS AGRICULTURE, MERIAL LIMITED
    Inventors: Mark David Soll, Loic Patrick Le Hir de Fallois, Scot Kevin Huber, Hyoung Ik Lee, Douglas Edward Wilkinson, Robert Toms Jacobs
  • Patent number: 8618126
    Abstract: The present invention relates to novel dihydroazole of formula (I) and salts thereof: Wherein R1, A1, A2, G, X and Y are as defined in the description, compositions thereof, processes for their preparation and their uses to prevent or treat parasitic infections or infestations in animals and as pesticides.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: December 31, 2013
    Assignee: Merial Limited
    Inventors: Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Douglas Edward Wilkinson, Brent Christopher Beck
  • Publication number: 20130324457
    Abstract: Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R1 is hydrogen, cyano, halogen, R8, formyl, —C(O)R8, —C(O)OR8, —C(O)NR9R10, or —C(S)NH2; R2 is R8 or —S(O)mR11; R3 is methyl, ethyl or C1-C4 haloalkyl; R4, R5 and R7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R12, —S(O)nR12 or SF5; Z is a nitrogen atom or C—R13; R8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R9 is hydrogen, alkyl, haloalkyl or alkoxy; R10 is hydrogen, alkyl, haloalkyl or alkoxy; R11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R12 is alkyl or haloalkyl; R13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.
    Type: Application
    Filed: May 15, 2013
    Publication date: December 5, 2013
    Applicants: AVENTIS AGRICULTURE, MERIAL LIMITED
    Inventors: Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Philip Reid Timmons, William Glenn Cawthorne, Jr., Alberto Perez de Leon
  • Publication number: 20130281710
    Abstract: Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
    Type: Application
    Filed: April 22, 2013
    Publication date: October 24, 2013
    Applicant: MERIAL LIMITED
    Inventors: Charles Q. Meng, Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Xinxi Zhan, Jean Robert Labrosse, Michel Mulhauser
  • Publication number: 20130256170
    Abstract: This invention relates to compositions for combating parasites in animals, comprising 1-arylpyrazole compounds alone or in combination with formamidine compounds. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infestation in an animal comprising administering the compositions of the invention to the animal in need thereof.
    Type: Application
    Filed: May 23, 2013
    Publication date: October 3, 2013
    Applicant: MERIAL LIMITED
    Inventors: Mark David Soll, Luiz Gustavo Cramer, Patrice Wurtz, James Pate, Natalya Shub, Loic Patrick Le Hir de Fallois, Philip Reid Timmons
  • Patent number: 8461176
    Abstract: The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives substantially enriched in an enantiomer of formula (I): and compounds of formula (IH) wherein R3, R4, R5, R6, R7, R13a, R13b, R14a, R14b, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: June 11, 2013
    Assignee: Merial Limited
    Inventors: Mark David Soll, Loic Patrick Le Hir de Fallois, Scot Kevin Huber, Hyoung Ik Lee, Douglas Edward Wilkinson, Robert Toms Jacobs, Brent Christopher Beck
  • Patent number: 8450357
    Abstract: This invention relates to compositions for combating parasites in animals, comprising 1-arylpyrazole compounds alone or in combination with formamidine compounds. This invention also provides for an improved methods for eradicating, controlling, and preventing parasite infestation in an animal comprising administering the compositions of the invention to the animal in need thereof.
    Type: Grant
    Filed: November 13, 2009
    Date of Patent: May 28, 2013
    Assignee: Merial Limited
    Inventors: Mark David Soll, Luiz Gustavo Cramer, James Pate, Natalya Shub, Loic Patrick Le Hir de Fallois, Philip Reid Timmons
  • Patent number: 8445519
    Abstract: Provided are 1-aryl-5-alkyl pyrazole compounds, of formula (I): wherein: R1 is hydrogen, cyano, halogen, R8, formyl, —C(O)R8, —C(O)OR8, —C(O)NR9R10, or —C(S)NH2; R2 is R8 or —S(O)mR11; R3 is methyl, ethyl or C1-C4 haloalkyl; R4, R5 and R7 are independently hydrogen, halogen, alkyl, haloalkyl, cyano or nitro; R6 is halogen, alkyl, haloalkyl, alkoxy, haloalkyloxy, cyano, nitro, —C(O)R12, —S(O)nR12 or SF5; Z is a nitrogen atom or C—R13; R8 is alkyl, haloalkyl, cycloalkyl or halocycloalkyl; R9 is hydrogen, alkyl, haloalkyl or alkoxy; R10 is hydrogen, alkyl, haloalkyl or alkoxy; R11 is alkyl, haloalkyl, alkenyl, haloalkenyl, alkynyl, haloalkynyl or cycloalkyl; R12 is alkyl or haloalkyl; R13 is hydrogen, halogen, cyano, nitro, alkyl, haloalkyl, alkoxy or haloalkoxy; m is 0, 1 or 2; and n is 0, 1 or 2; or a salt thereof, the method of making compounds of formula (I) and the use of these compounds against ectoparasites, endoparasites and pests.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: May 21, 2013
    Assignee: Aventis Agriculture
    Inventors: Hyoung Ik Lee, Loïc Patrick Le Hir de Fallois, Philip Reid Timmons, William Glenn Cawthorne, Jr., Adalberto Perez de Leon
  • Patent number: 8314146
    Abstract: The present invention relates to novel thioamide derivatives of formula (I) and formula (Ia): wherein, R3, R4, R5, R6, R7, P, Q, T, V, W, X, Y, Z, a, m and n are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Grant
    Filed: April 13, 2011
    Date of Patent: November 20, 2012
    Assignee: Merial Limited
    Inventors: Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Philip Reid Timmons
  • Patent number: 8283475
    Abstract: The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Grant
    Filed: December 14, 2011
    Date of Patent: October 9, 2012
    Assignees: Merial Limited, Aventis Agriculture
    Inventors: Mark David Soll, Loïc Patrick Le Hir de Fallois, Scot Kevin Huber, Hyoung Ik Lee, Douglas Edward Wilkinson, Robert Toms Jacobs
  • Publication number: 20120149750
    Abstract: The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Application
    Filed: December 14, 2011
    Publication date: June 14, 2012
    Inventors: Mark David Soll, Loïc Patrick Le Hir de Fallois, Scot Kevin Huber, Hyoung Ik Lee, Douglas Edward Wilkinson, Robert Toms Jacobs
  • Patent number: 8088801
    Abstract: The present invention relates to novel aryloazol-2-yl-cyanoethylamino derivatives of formula (I): wherein R3, R4, R5, R6, R7, P, Q, V, W, X, Y, Z and a are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Grant
    Filed: May 12, 2008
    Date of Patent: January 3, 2012
    Assignees: Merial Limited, Aventis Agiziculture
    Inventors: Mark David Soll, Loïc Patrick Le Hir de Fallois, Scot Kevin Huber, Hyoung Ik Lee, Douglas Edward Wilkinson, Robert Toms Jacobs
  • Publication number: 20110190231
    Abstract: The present invention relates to novel thioamide derivatives of formula (I) and formula (Ia): wherein, R3, R4, R5, R6, R7, P, Q, T, V, W, X, Y, Z, a, m and n are as defined in the description, compositions thereof, processes for their preparation and their uses as pesticides.
    Type: Application
    Filed: April 13, 2011
    Publication date: August 4, 2011
    Inventors: Loic Patrick Le Hir de Fallois, Hyoung Ik Lee, Philip Reid Timmons