Abstract: There is provided a holder (300) for an inhaler article (200), the holder (300) comprising an inhalation volume estimator (350) and an air flow passage (322). The inhalation volume estimator (350) comprises a turbine (352) and an indicator coupled to the turbine (352) for indicating inhalation volume information relating to a volume of an air flow through the air flow passage (322). In use, the turbine (352) is configured to rotate in response to air flow through the air flow passage (322) and alter the inhalation volume information indicated by the indicator. An inhalation system (100) comprising the holder (300) is also provided.

Abstract: An inhalation counter (350, 450, 550) for an inhalation system (100) is provided. The inhalation system comprises a fluid flow passage (322) and the inhalation counter comprises an escapement wheel (352, 452), a biasing means (354, 454) for incrementing the escapement wheel, a conversion mechanism which, in use, is configured to perform a first action in response to a temporary increase in fluid flow rate through the fluid flow passage, and an anchor (356, 456). The anchor is coupled to the conversion mechanism and configured to interact with the escapement wheel so as to allow the biasing means to increment the escapement wheel in response to the first action of the conversion mechanism. A holder (300) and an inhalation system comprising the inhalation counter are also provided.

Abstract: An ultrasonic cutting tool for use in an ultrasonic instrument, the tool being a blade manufactured from a tubular blank by flattening a section of the blank. The blade includes a flat section designed to be used for cutting, a tubular section, and a transition section joining the flat section to the tubular section. The tubular section is joined to or includes an attachment section for attaching the blade to an ultrasonic generator and serving as a conduit to bring a cooling fluid to the distal end or to suck particles into the hand tool.

Abstract: An ultrasonic cutting tool is designed for use in an ultrasonic instrument. The tool is a blade having a flat section manufactured from at least a first blade layer and second blade layer. The first and second blade layer each being a flat metal plate arranged in parallel to one another and bonded to one another.

Abstract: The invention resides in the field of medical technology. It relates in particular to a sonotrode suitable for use with an ultrasonic surgical instrument. The invention refers further to an ultrasonic surgical instrument for cutting or punching bones, including such a sonotrode as well as a method for manufacturing the sonotrode of the invention.

Abstract: A method for cell stimulation by mechanical energy as well as a method for determining a subject specific set of treatment parameters for acoustic wave stimulation and a method for validating a set of treatment parameters for acoustic wave stimulation. The method for determining a subject specific set of treatment parameters includes generating subject specific data, which includes measuring a geometric property of a body portion, and determining a target field distribution in the body portion. The method for validating a set of treatment parameters for acoustic wave stimulation includes determining a target field distribution of an acoustic field in a body portion, receiving a related set of treatment parameters for at least one transducer, generating a subject specific 3D model of the body portion, and determining a difference between the target field distribution and a field distribution determined in the subject specific 3D model.

Abstract: The invention relates to the field of cell stimulation by mechanical energy, in particular by acoustic energy, for example stimulation by ultrasound, such as focused ultrasound (FUS). It relates to treatment devices and components thereof as well as methods for setting up or producing such devices or components. One purpose of the invention is to make devices for cell stimulation by mechanical energy more user friendly and applicable for a wider public and for additional applications. A treatment device for acoustic wave stimulation to a body portion is portable and includes a carrier element, at least one transducer and communication device configured to receive operating parameters for the at least one transducer from a remote computerized device. A method for setting up a treatment device for acoustic wave stimulation includes receiving operating parameters for the at least one transducer from a remote computerized device.

Abstract: A sonotrode includes a stem extending along a longitudinal axis and a cap configured to carry out an ablative process on tissue using mechanical oscillation. The cap has at least one portion that protrudes further in a radial direction than the stem, and the at least one portion has at least one sharp rim. A surface of the cap, which is arranged between a distal end of the stem and the sharp rim of the portion, is a concave surface and/or runs at an opening angle with respect to the stem that is equal or smaller than 90 degrees. A center of mass of the cap is on the longitudinal axis.

Abstract: A sonotrode suitable for use with an ultrasonic surgical instrument for cutting or punching bones, as well as a method for manufacturing the sonotrode.

Abstract: A device for cutting bone tissue and, more particularly, a sonotrode suitable for use with an ultrasonic surgical instrument. The sonotrode has a head and a distal end piece, the distal end piece being equipped as a rectangular blade for cutting bones using mechanical vibration. The sonotrode has at least one structural element and the structural element is selected from the group including: a support structure, a lateral depression on each side, an increased width of the blade together with a slit at the distal end of the blade, or at least one lateral rib.

Abstract: A cleaning tool for an aerosol-generating device is provided, the cleaning tool including an elongate body having a proximal end portion and a distal end portion, the distal end portion defining a recess configured to receive a heating element of an aerosol-generating device, the recess extending from an opening in a distal end face of the elongate body towards the proximal end portion of the elongate body, the distal end portion of the elongate body being provided with at least one protrusion inwardly projecting into the recess, and the elongate body further including a scraping surface at the distal end face of the elongate body.

Abstract: The invention resides in the field of medical technology. It relates in particular to a sonotrode suitable for use with an ultrasonic surgical instrument. The invention refers further to an ultrasonic surgical instrument for cutting or punching bones, including such a sonotrode as well as a method for manufacturing the sonotrode of the invention.