Abstract: Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form of MTX, the duration of which lasts from about 1 to about 30 days. Also disclosed are methods of treating autoimmune diseases and cancer by administering these formulations of MTX.

Abstract: Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form of MTX, the duration of which lasts from about 1 to about 30 days. Also disclosed are methods of treating autoimmune diseases and cancer by administering these formulations of MTX.

Abstract: The present invention is a disposable garment, such as a glove, a sock, or a shoe, for treating foot or hand inflammation or disease. In a preferred embodiment, the garment comprises a flexible outer cover that is nonporous and an inner layer closely adhered to the inside of the outer cover. The outer cover may preferably have a flexible closure at the level of the ankle or wrist, arranged such that liquids will be retained therein. The inner layer serves as a reservoir for a selected therapeutic product, and preferably comprises a bladder. Preferably, the bladder has a perforation, and may be disposed within the inner layer in a position allowing a user to apply pressure to bladder with his foot or hand. A therapeutic product in liquid form is stored within the reservoir, and is released upon application of pressure by the user's foot or hand.

Abstract: Disclosed is are formulations comprising a multivesicular liposome and MTX, the administration of which results in a Cmax of MTX between 5% and 50% of the Cmax of an immediate release dosage form of MTX, the duration of which lasts from about 1 to about 30 days. Also disclosed are methods of treating autoimmune diseases and cancer by administering these formulations of MTX.

Abstract: Software and a system created by the software with its application are applied in the healthcare setting for various patients corresponding to the CMS or JCAHO core measures. The software and its system captures necessary patient data related to future P4P initiatives designed by federal authorities, private payors or other organizations plus report safety events. The software allows real-time data entry at the bedside, during patient care processes, from admission to discharge. The system provides real-time feedback to practitioners on their performance as well as hospital benchmarking. The software can be used on a variety of hardware devices, and may gather data from various hospital information systems.