Patents by Inventor Lone Kierstein Nielsen

Lone Kierstein Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220372461
    Abstract: The invention provides liquid enzyme compositions which are physically and microbially stable. The compositions are used, for example, in beer brewing processes.
    Type: Application
    Filed: November 6, 2020
    Publication date: November 24, 2022
    Applicant: Novozymes A/S
    Inventor: Lone Kierstein Nielsen
  • Publication number: 20200157472
    Abstract: Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.
    Type: Application
    Filed: January 22, 2020
    Publication date: May 21, 2020
    Applicant: Novozymes A/S
    Inventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
  • Patent number: 10577568
    Abstract: Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.
    Type: Grant
    Filed: November 11, 2009
    Date of Patent: March 3, 2020
    Assignee: Novozymes A/S
    Inventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
  • Patent number: 9181296
    Abstract: Peptide aldehydes or ketone derivatives are particularly efficient for stabilizing subtilisin-type proteases in aqueous compositions such as liquid detergents, including peptide compounds with OH-substituted phenylalanine aldehyde as the C-terminal residue.
    Type: Grant
    Filed: March 26, 2009
    Date of Patent: November 10, 2015
    Assignee: NOVOZYMES A/S
    Inventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen, Lotte Rugholm Soerensen
  • Publication number: 20110301071
    Abstract: The present invention relates to a liquid composition comprising an enzyme and an enzyme stabilizer such as an aryl carboxylic acid.
    Type: Application
    Filed: August 10, 2011
    Publication date: December 8, 2011
    Applicant: Novozymes A/S
    Inventors: Lone Kierstein Nielsen, Ole Simonsen, Karl Werntoft, Niclas Ilestam
  • Patent number: 8071345
    Abstract: The present invention relates to a liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer that is 3-chlorobenzoic acid, 4-chlorobenzoic acid, 3-chlorophenylacetic acid, 3,5-dichlorobenzoic acid, 3-(3-chlorophenyl)propionic acid or their corresponding salts. The composition can further comprise a another enzyme that is a lipase, an amylase, a cellulase or mixtures thereof. The stabilizer can be present at a concentration of 0.001 to 20% w/w. The concentration of the subtilisin can be at least 1.5 g/L.
    Type: Grant
    Filed: March 29, 2007
    Date of Patent: December 6, 2011
    Assignee: Novozymes A/S
    Inventors: Lone Kierstein Nielsen, Ole Simonsen, Karl Werntoft, Niclas Ilestam
  • Publication number: 20110212877
    Abstract: Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.
    Type: Application
    Filed: November 11, 2009
    Publication date: September 1, 2011
    Applicant: Novozymes A/S
    Inventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
  • Publication number: 20110039752
    Abstract: Peptide aldehydes or ketone derivatives are particularly efficient for stabilizing subtilisin-type proteases in aqueous compositions such as liquid detergents, including peptide compounds with OH-substituted phenylalanine aldehyde as the C-terminal residue.
    Type: Application
    Filed: March 26, 2009
    Publication date: February 17, 2011
    Applicant: NOVOZYMES A/S
    Inventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen, Lotte Rugholm Soerensen
  • Publication number: 20110034367
    Abstract: Incorporation of a serine protease inhibitor such as RASI, BASI, WASI (bifunctional alpha-amylase/subtilisin inhibitors of rice, barley and wheat) into a liquid detergent which contains a serine proteasecan stabilize the serine protease and/or a second enzyme and can release the enzyme when the detergent composition is diluted.
    Type: Application
    Filed: January 29, 2009
    Publication date: February 10, 2011
    Inventors: Ole Simonsen, Juergen Carsten Franz Knoetzel, Lone Kierstein Nielsen
  • Publication number: 20070232514
    Abstract: The present invention relates to a liquid composition comprising an enzyme and an enzyme stabilizer of the following formula: or a salt thereof, wherein R1 is selected from the group consisting of C0-C5 alkyl, substituted C1-C5 alkyl, C1-C5 alkenyl and substituted C1-C6 akenyl and R2, R3, R4, R5 and R6 is selected from the group consisting of hydrogen, C1-C6 alkyl, substituted C1 to C6 alkyl, aryl, substituted aryl, hydroxyl, hydroxyl derivative, amine, C1-C6 alkylated amine, amine derivative, halogen, nitro, thiol, thiol derivative, aldehyde, acid, acid salt, ester, sulfonate or phosphonate.
    Type: Application
    Filed: March 29, 2007
    Publication date: October 4, 2007
    Applicant: Novozymes A/S
    Inventors: Lone Kierstein Nielsen, Ole Simonsen, Karl Werntoft, Niclas Ilestam
  • Patent number: 5985629
    Abstract: Contact lens are cleaned and disinfected by contacting with an enzyme that functions as a cleaning agent by degrading deposits on the lens, and with an enzyme inhibitor that inhibits remaining enzyme activity and a mild disinfecting agent. If rinsing of the lens is not carried out after cleaning and disinfecting, this procedure prevents eye damage by inhibiting remaining enzyme activity and using a mild disinfectant. Preferred enzymes are proteases such as an acidic aspartic protease, a cysteine protease, a serine protease or a metalloprotease, and preferred enzyme inhibitors function both as an inhibitor and as a mild disinfectant such as chloramine-T, chloramine-B, bacitracin or aryl boronic acids. In a preferred method, the enzyme is subtilisin A and the enzyme inhibitor and disinfectant is chloramine-T.
    Type: Grant
    Filed: February 12, 1997
    Date of Patent: November 16, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Dorrit Aaslyng, Jack Bech Nielsen, Lone Kierstein Nielsen
  • Patent number: 5972873
    Abstract: The present invention relates to a liquid composition comprising an enzyme and a phenyl boronic acid derivative enzyme stabilizer of the following formula: ##STR1## wherein R is selected from the group consisting of hydrogen, hydroxy, C.sub.1 -C.sub.6 alkyl, substituted C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl and substituted C.sub.1 -C.sub.6 alkenyl.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: October 26, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Lone Kierstein Nielsen, Allison Deane-Wray
  • Patent number: 5968887
    Abstract: The invention relates to a liquid composition which comprises an enzyme and a enzyme stabilizing component. The enzyme stabilizing component is a boronic acid derivative.
    Type: Grant
    Filed: July 9, 1998
    Date of Patent: October 19, 1999
    Assignee: Novo Nordisk A/S
    Inventors: Lone Kierstein Nielsen, Allison Deane-Wray
  • Patent number: 5840677
    Abstract: The invention relates to a detergent composition comprising an enzyme and a boronic acid or borinic acid derivative which acts as a stabilizer for the enzyme in detergent compositions. Specific boronic acid inhibiters include benzofuran substituted boronic acids.
    Type: Grant
    Filed: January 25, 1996
    Date of Patent: November 24, 1998
    Assignees: Novo Nordisk A/S, Borax Consolidated Ltd.
    Inventors: Lone Kierstein Nielsen, Allison Deane-Wray
  • Patent number: 5834415
    Abstract: A liquid detergent composition comprising a surfactant, an enzyme and a naphthalene boronic acid derivative enzyme stabilizer.
    Type: Grant
    Filed: October 21, 1996
    Date of Patent: November 10, 1998
    Assignee: Novo Nordisk A/S
    Inventors: Lone Kierstein Nielsen, Allison Deane-Wray