Patents by Inventor Lone Kierstein Nielsen
Lone Kierstein Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20220372461Abstract: The invention provides liquid enzyme compositions which are physically and microbially stable. The compositions are used, for example, in beer brewing processes.Type: ApplicationFiled: November 6, 2020Publication date: November 24, 2022Applicant: Novozymes A/SInventor: Lone Kierstein Nielsen
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Publication number: 20200157472Abstract: Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.Type: ApplicationFiled: January 22, 2020Publication date: May 21, 2020Applicant: Novozymes A/SInventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
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Patent number: 10577568Abstract: Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.Type: GrantFiled: November 11, 2009Date of Patent: March 3, 2020Assignee: Novozymes A/SInventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
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Patent number: 9181296Abstract: Peptide aldehydes or ketone derivatives are particularly efficient for stabilizing subtilisin-type proteases in aqueous compositions such as liquid detergents, including peptide compounds with OH-substituted phenylalanine aldehyde as the C-terminal residue.Type: GrantFiled: March 26, 2009Date of Patent: November 10, 2015Assignee: NOVOZYMES A/SInventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen, Lotte Rugholm Soerensen
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Publication number: 20110301071Abstract: The present invention relates to a liquid composition comprising an enzyme and an enzyme stabilizer such as an aryl carboxylic acid.Type: ApplicationFiled: August 10, 2011Publication date: December 8, 2011Applicant: Novozymes A/SInventors: Lone Kierstein Nielsen, Ole Simonsen, Karl Werntoft, Niclas Ilestam
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Patent number: 8071345Abstract: The present invention relates to a liquid detergent composition comprising a surfactant, a subtilisin and a protease stabilizer that is 3-chlorobenzoic acid, 4-chlorobenzoic acid, 3-chlorophenylacetic acid, 3,5-dichlorobenzoic acid, 3-(3-chlorophenyl)propionic acid or their corresponding salts. The composition can further comprise a another enzyme that is a lipase, an amylase, a cellulase or mixtures thereof. The stabilizer can be present at a concentration of 0.001 to 20% w/w. The concentration of the subtilisin can be at least 1.5 g/L.Type: GrantFiled: March 29, 2007Date of Patent: December 6, 2011Assignee: Novozymes A/SInventors: Lone Kierstein Nielsen, Ole Simonsen, Karl Werntoft, Niclas Ilestam
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Publication number: 20110212877Abstract: Peptide aldehydes containing a ureido group are effective as stabilizers for protease in a detergent composition, and as stabilizers for a second enzyme in a liquid composition with a protease.Type: ApplicationFiled: November 11, 2009Publication date: September 1, 2011Applicant: Novozymes A/SInventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen
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Publication number: 20110039752Abstract: Peptide aldehydes or ketone derivatives are particularly efficient for stabilizing subtilisin-type proteases in aqueous compositions such as liquid detergents, including peptide compounds with OH-substituted phenylalanine aldehyde as the C-terminal residue.Type: ApplicationFiled: March 26, 2009Publication date: February 17, 2011Applicant: NOVOZYMES A/SInventors: Lone Kierstein Nielsen, Lise Munch Mikkelsen, Esben Peter Friis, Juergen Carsten Franz Knoetzel, Ole Simonsen, Lotte Rugholm Soerensen
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Publication number: 20110034367Abstract: Incorporation of a serine protease inhibitor such as RASI, BASI, WASI (bifunctional alpha-amylase/subtilisin inhibitors of rice, barley and wheat) into a liquid detergent which contains a serine proteasecan stabilize the serine protease and/or a second enzyme and can release the enzyme when the detergent composition is diluted.Type: ApplicationFiled: January 29, 2009Publication date: February 10, 2011Inventors: Ole Simonsen, Juergen Carsten Franz Knoetzel, Lone Kierstein Nielsen
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Publication number: 20070232514Abstract: The present invention relates to a liquid composition comprising an enzyme and an enzyme stabilizer of the following formula: or a salt thereof, wherein R1 is selected from the group consisting of C0-C5 alkyl, substituted C1-C5 alkyl, C1-C5 alkenyl and substituted C1-C6 akenyl and R2, R3, R4, R5 and R6 is selected from the group consisting of hydrogen, C1-C6 alkyl, substituted C1 to C6 alkyl, aryl, substituted aryl, hydroxyl, hydroxyl derivative, amine, C1-C6 alkylated amine, amine derivative, halogen, nitro, thiol, thiol derivative, aldehyde, acid, acid salt, ester, sulfonate or phosphonate.Type: ApplicationFiled: March 29, 2007Publication date: October 4, 2007Applicant: Novozymes A/SInventors: Lone Kierstein Nielsen, Ole Simonsen, Karl Werntoft, Niclas Ilestam
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Patent number: 5985629Abstract: Contact lens are cleaned and disinfected by contacting with an enzyme that functions as a cleaning agent by degrading deposits on the lens, and with an enzyme inhibitor that inhibits remaining enzyme activity and a mild disinfecting agent. If rinsing of the lens is not carried out after cleaning and disinfecting, this procedure prevents eye damage by inhibiting remaining enzyme activity and using a mild disinfectant. Preferred enzymes are proteases such as an acidic aspartic protease, a cysteine protease, a serine protease or a metalloprotease, and preferred enzyme inhibitors function both as an inhibitor and as a mild disinfectant such as chloramine-T, chloramine-B, bacitracin or aryl boronic acids. In a preferred method, the enzyme is subtilisin A and the enzyme inhibitor and disinfectant is chloramine-T.Type: GrantFiled: February 12, 1997Date of Patent: November 16, 1999Assignee: Novo Nordisk A/SInventors: Dorrit Aaslyng, Jack Bech Nielsen, Lone Kierstein Nielsen
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Patent number: 5972873Abstract: The present invention relates to a liquid composition comprising an enzyme and a phenyl boronic acid derivative enzyme stabilizer of the following formula: ##STR1## wherein R is selected from the group consisting of hydrogen, hydroxy, C.sub.1 -C.sub.6 alkyl, substituted C.sub.1 -C.sub.6 alkyl, C.sub.1 -C.sub.6 alkenyl and substituted C.sub.1 -C.sub.6 alkenyl.Type: GrantFiled: November 21, 1997Date of Patent: October 26, 1999Assignee: Novo Nordisk A/SInventors: Lone Kierstein Nielsen, Allison Deane-Wray
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Patent number: 5968887Abstract: The invention relates to a liquid composition which comprises an enzyme and a enzyme stabilizing component. The enzyme stabilizing component is a boronic acid derivative.Type: GrantFiled: July 9, 1998Date of Patent: October 19, 1999Assignee: Novo Nordisk A/SInventors: Lone Kierstein Nielsen, Allison Deane-Wray
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Patent number: 5840677Abstract: The invention relates to a detergent composition comprising an enzyme and a boronic acid or borinic acid derivative which acts as a stabilizer for the enzyme in detergent compositions. Specific boronic acid inhibiters include benzofuran substituted boronic acids.Type: GrantFiled: January 25, 1996Date of Patent: November 24, 1998Assignees: Novo Nordisk A/S, Borax Consolidated Ltd.Inventors: Lone Kierstein Nielsen, Allison Deane-Wray
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Patent number: 5834415Abstract: A liquid detergent composition comprising a surfactant, an enzyme and a naphthalene boronic acid derivative enzyme stabilizer.Type: GrantFiled: October 21, 1996Date of Patent: November 10, 1998Assignee: Novo Nordisk A/SInventors: Lone Kierstein Nielsen, Allison Deane-Wray