Patents by Inventor Lone Kjær Rasmussen

Lone Kjær Rasmussen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
    Patent number: 9029091
    Abstract: The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of the final polyclonal products. The structural characterization platform is based on genetic analysis as well as protein characterization techniques that alone or in combination provides the necessary information to characterize the polyclonal cell line and final products. The collection of different homologous proteins to be analyzed with the platform techniques is for example a recombinant polyclonal antibody or a mixture of monoclonal antibodies.
    Type: Grant
    Filed: October 16, 2012
    Date of Patent: May 12, 2015
    Assignee: Symphogen A/S
    Inventors: Lone Kjær Rasmussen, Torben Frandsen, Søren Kofoed Rasmussen, Peter Sejer Andersen
  • Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line
    Patent number: 8288109
    Abstract: The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of the final polyclonal products. The structural characterization platform is based on genetic analyses as well as protein characterization techniques that alone or in combination provide the necessary information to characterize the polyclonal cell line and final products. The collection of different homologous proteins to be analyzed with the platform techniques if for example a recombinant polyclonal antibody or a mixture of monoclonal antibodies.
    Type: Grant
    Filed: July 20, 2005
    Date of Patent: October 16, 2012
    Assignee: Symphogen A/S
    Inventors: Lone Kjaer Rasmussen, Torben Frandsen, Soren Kofoed Rasmussen, Peter Sejer Andersen
  • ANTI-ORTHOPOXVIRUS RECOMBINANT POLYCLONAL ANTIBODY
    Publication number: 20110158984
    Abstract: Disclosed is an anti-orthopoxvirus recombinant polyclonal antibody comprising distinct members which in union are capable of binding at least three orthopoxvirus related antigens, a pharmaceutical composition comprising the antibody, and a method for its production. Also disclosed is a polyclonal cell line capable of producing the recombinant polyclonal antibody as therapeutic methods utilizing the polyclonal antibody. Finally, the invention also pertains to a method for screening for useful VH and VL pairs useful when preparing the polyclonal antibody.
    Type: Application
    Filed: December 10, 2010
    Publication date: June 30, 2011
    Applicant: Symphogen A/S
    Inventors: Allan Jensen, Johan Lantto, Margit Haahr Hansen, Lone Kjær Rasmussen, Søren Kofoed Rasmussen, Lucilla Steinaa
  • Anti-orthopoxvirus recombinant polyclonal antibody
    Patent number: 7850965
    Abstract: Disclosed is an anti-orthopoxvirus recombinant polyclonal antibody comprising distinct members which in union are capable of binding at least three orthopoxvirus related antigens, a pharmaceutical composition comprising the antibody, and a method for its production. Also disclosed is a polyclonal cell line capable of producing the recombinant polyclonal antibody as therapeutic methods utilizing the polyclonal antibody. Finally, the invention also pertains to a method for screening for useful VH and VL pairs useful when preparing the polyclonal antibody.
    Type: Grant
    Filed: December 4, 2006
    Date of Patent: December 14, 2010
    Assignee: Symphogen A/S
    Inventors: Allan Jensen, Johan Lantto, Margit Haahr Hansen, Lone Kjær Rasmussen, Søren Kofoed Rasmussen, Lucilla Steinaa
  • Method for Characterization of a Recombinant Polyclonal Protein
    Publication number: 20090186423
    Abstract: The present invention provides a characterization platform that can be used to assess the amount of different antibodies produced by a polyclonal cell line during production, as well as batch-to-batch consistency of the antibodies present in the polyclonal products. The structural characterization platform is based on removal of the heavy chains and separation of the light chains remaining via a chromatographic separation technique followed by mass spectrometry analysis on the intact light chain species.
    Type: Application
    Filed: November 20, 2008
    Publication date: July 23, 2009
    Applicant: Symphogen A/S
    Inventors: Torben P. FRANDSEN, Lone Kjaer RASMUSSEN, Anders ENGSTROM, Erland HOLMBERG, Pia PERSSON
  • Procedure for Structural Characterization of a Recombinant Polylonal Protein or a Polyclonal Cell Line
    Publication number: 20080131882
    Abstract: The present invention provides a structural characterization platform that can be used to assess the stability of a polyclonal cell line during production, as well as batch-to-batch consistency of the final polyclonal products. The structural characterization platform is based on genetic analyses as well as protein characterization techniques that alone or in combination provide the necessary information to characterize the polyclonal cell line and final products. The collection of different homologous proteins to be analyzed with the platform techniques if for example a recombinant polyclonal antibody or a mixture of monoclonal antibodies.
    Type: Application
    Filed: July 20, 2005
    Publication date: June 5, 2008
    Applicant: Symphogen A/S
    Inventors: Lone Kjaer Rasmussen, Torben Frandsen, Soren Kofoed Rasmussen, Peter Sejer Andersen