Patents by Inventor Lone Nielsen

Lone Nielsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 3-(5-isoxazolyl)-1-methyl-1,2,3,6-tetrahydropyridine useful for treating Alzheimer's disease
    Patent number: 5356912
    Abstract: Novel azacyclic compounds selected from the group consisting of ##STR1## wherein R.sup.1 is H or C.sub.1-6 -alkylR.sup.3 is ##STR2## R" is H or C.sub.1-8 -alkyl or C.sub.1-6 -alkoxy or C.sub.1-4 -alkoxy-C.sub.1-4 -alkyl or aryl, andR.sup.4 is H, C.sub.1-8 -alkyl or Cl;and a salt thereof with a pharmaceutically-acceptable acid.The new compounds are useful in improving the cognitive functions of the forebrain and hippocampus of mammals, and are useful in the treatment of Alzheimer's disease.
    Type: Grant
    Filed: November 12, 1993
    Date of Patent: October 18, 1994
    Assignee: Novo Nordisk A/S
    Inventors: Lone Nielsen, Frank Watjen, Jens W. Kindtler, Preben H. Olesen, Per Sauerberg