Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: A supercomputer system having at least one server, a plurality of compute clients and a distributed file system. The server is configured to distribute computation tickets and each compute client is configured to request a computation ticket. The distributed file system is configured to stock input data for all tasks and output data produced by the compute clients. The supercomputer system is characterized in that it further includes at least one I/O client configured to exchange data with each compute client and with the distributed file system, to distribute input data to at least some of the compute clients or to collect output data produced by at least some of the compute clients.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: A method of data compression performed by at least one core communicating with a central memory. The input data presents a two-dimensional input array formed by a plurality data items stored contiguously in the central memory according to a contiguous direction. The method comprises a step of wavelet transform comprising the following sub-steps: forming from the input array at least one tile comprising a plurality of consecutive data block columns, each data block column being formed by a plurality of lines of consecutive data items according to the contiguous direction, the length of each line being a multiple of the cache line length; and for each data block column computing dot products between a filter vector and each group of N lines using fused multiply-add instructions for the core.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: A supercomputer system having at least one server, a plurality of compute clients and a distributed file system. The server is configured to distribute computation tickets and each compute client is configured to request a computation ticket. The distributed file system is configured to stock input data for all tasks and output data produced by the compute clients. The supercomputer system is characterized in that it further includes at least one I/O client configured to exchange data with each compute client and with the distributed file system, to distribute input data to at least some of the compute clients or to collect output data produced by at least some of the compute clients.

Abstract: A method of data compression performed by at least one core communicating with a central memory. The input data presents a two-dimensional input array formed by a plurality data items stored contiguously in the central memory according to a contiguous direction. The method comprises a step of wavelet transform comprising the following sub-steps: forming from the input array at least one tile comprising a plurality of consecutive data block columns, each data block column being formed by a plurality of lines of consecutive data items according to the contiguous direction, the length of each line being a multiple of the cache line length; and for each data block column computing dot products between a filter vector and each group of N lines using fused multiply-add instructions for the core.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular weight material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: The present invention belongs to the pharmaceutical field, and in particular, it relates to a pharmaceutical formulation of palbociclib and a preparation method thereof. The pharmaceutical formulation comprises palbociclib, an acidic auxiliary material, and optionally a hydrophilic high-molecular material, which has better solubility and in vitro dissolution property as compared with the conventional formulation and can be used for enhancing in vivo absorption and bioavailability of palbociclib.

Abstract: An adapter card is used to convert the PCI Express X1 slot to CompactPCI Express X1 slot which is compatible with PICMG EXP.0 R1.0 specification in the commercial and industrial control computer. The adapter card includes the impedance controlled circuit board, the connecting circuit board, the PCI Express port, the CPCI Express signal socket, the CPCI power socket, the double row hole socket, the double row bent needle plug, the linking block and a dam-board. The adapter card expands the application of PCI Express X1 slots by a large margin and make it compatible with CPCI Express X1 card.