Abstract: Methods and apparatuses to detect configuration commands from waveforms received at a retina prosthesis device for calibrating the device are described. The device can comprise an array of pixel units to receive light to stimulate neuron cells to cause an effect of visual sensation from the light. The pixel units may have configurable parameters for the stimulation to the neuron cells. The configurable parameters may be updated according to the configuration commands detected without requiring micro processor and non-volatile memory in the device. The stimulation may be generated according to the updated configurable parameters to improve the effect of visual sensation from the light including compensation for the physiological and environmental variations and drifts.

Abstract: An artificial retinal prosthesis is disclosed, which comprises a plurality of pixel group units to output a spatiotemporal electrical stimulation for inducing color perception. Each of the pixel group units comprises a main pixel unit and at least one surrounding pixel unit. The main pixel unit and the surrounding pixel unit respectively outputs an electrical stimulation waveform according to a first stimulation cycle and a second stimulation cycle. Both of the first stimulation cycle and the second stimulation cycle have a first-half duration and a second-half duration. The first-half duration of the first stimulation cycle has inactive period greater than 20% and less than 80% and the rest of the first stimulation cycle is active period. The second-half duration of the first stimulation cycle is inactive period. The first-half duration of the second stimulation cycle is active period and the second-half duration of the second stimulation cycle is inactive period.

Abstract: An artificial prosthesis is disclosed, which comprises a pixel array, a correlated double sampling unit, an analog-to-digital converter, a digital core, and a digital-to-analog converter. The digital core is configured to perform a calculation of electrical stimulation waveform of each of the pixels by using a processing function of an ANN. As such, the neural stimulation levels for artificial vision can be optimized.

Abstract: The invention provides a chip assembly for implantation into a living tissue comprising an electronic element and a biocompatible buffer material. The electronic element is defined to form a first contour, the first contour comprises at least one sharp edge exposed outside, and the buffer material covers the sharp edge and blocks the sharp edge to avoid damage to the living tissue.

Abstract: The present invention relates to a method for testing a retinal implant. After an implantable device for interfacing with retinal cells is provided, an external stimulus is applied to the implantable device so that the implantable device transmits a first pulse to a processing device through a wireless interface. When a conversion unit is controlled to gradually decrease an output voltage until the implantable device outputs an output voltage lower than a reference voltage, the implantable device transmits a signal different from the first pulse to the processing device through the wireless interface. The processing device determines a current value of a pixel unit according to a time difference between the first pulse and the signal.

Abstract: The present invention discloses a high density retinal prosthesis system with equalization comprises a retinal prosthesis chip, a measuring device, a tuning device, and a transmitting device. After the measuring device capable of generating electrical induction with the retinal prosthesis chip obtains a degree of light stimulation received by pixel units in the retinal prosthesis chip, it is equalized by the tuning device, and then a calibration signal is fed to the pixel units to tune the pixel units to make the pixel units in the retinal prosthesis system to achieve an equalization effect.

Abstract: Methods and apparatuses to detect configuration commands from waveforms received at a retina prosthesis device for calibrating the device are described. The device can comprise an array of pixel units to receive light to stimulate neuron cells to cause an effect of visual sensation from the light. The pixel units may have configurable parameters for the stimulation to the neuron cells. The configurable parameters may be updated according to the configuration commands detected without requiring micro processor and non-volatile memory in the device. The stimulation may be generated according to the updated configurable parameters to improve the effect of visual sensation from the light including compensation for the physiological and environmental variations and drifts.

Abstract: The invention provides a system for artificial retinal prosthesis with color vision comprising an artificial retinal prosthesis implanted in a user's body. The artificial retinal prosthesis comprises a plurality of pixel units and a color shutter integrated with the plurality of pixel units structurally. The plurality of pixel units are used to receive an external visual image that enters the eyes of the user, and output a spatiotemporal electrical stimulation to the user's optic nerve according to the external visual image. The color shutter connects with the plurality of pixel units, and determines a spectrum that is allowed to enter the eyes to allow the user to generate a color image perception. By allowing stimulation of the artificial retinal prosthesis to vary with different spaces and times, and synchronously controlling the spectrum that is allowed to enter the eyes, thereby assisting the patient in obtaining color visual perception.

Abstract: The present invention relates to a system for artificial retinal prosthesis comprising a pixel array, a correlated double sampling unit, an analog-to-digital converter, a digital core, and a digital-to-analog converter. The system stimulates retinal cells row-to-row, and therefore can effectively reduce large transient currents and avoid unfavorable condition of power drop due to large transient currents.

Abstract: The present invention relates to a method for testing a retinal implant. After an implantable device for interfacing with retinal cells is provided, an external stimulus is applied to the implantable device so that the implantable device transmits a first pulse to a processing device through a wireless interface. When a conversion unit is controlled to gradually decrease an output voltage until the implantable device outputs an output voltage lower than a reference voltage, the implantable device transmits a signal different from the first pulse to the processing device through the wireless interface. The processing device determines a current value of a pixel unit according to a time difference between the first pulse and the signal.

Abstract: Methods and apparatuses to detect configuration commands from waveforms received at a retina prosthesis device for calibrating the device are described. The device can comprise an array of pixel units to receive light to stimulate neuron cells to cause an effect of visual sensation from the light. The pixel units may have configurable parameters for the stimulation to the neuron cells. The configurable parameters may be updated according to the configuration commands detected without requiring micro processor and non-volatile memory in the device. The stimulation may be generated according to the updated configurable parameters to improve the effect of visual sensation from the light including compensation for the physiological and environmental variations and drifts.

Abstract: Methods and apparatuses to detect configuration commands from waveforms received at a retina prosthesis device for calibrating the device are described. The device can comprise an array of pixel units to receive light to stimulate neuron cells to cause an effect of visual sensation from the light. The pixel units may have configurable parameters for the stimulation to the neuron cells. The configurable parameters may be updated according to the configuration commands detected without requiring micro processor and non-volatile memory in the device. The stimulation may be generated according to the updated configurable parameters to improve the effect of visual sensation from the light including compensation for the physiological and environmental variations and drifts.

Abstract: An implant apparatus comprising a plurality of photo sensors, a plurality of micro electrodes, a plurality of guard rings surrounding the micro electrodes and circuitry coupled to the photo sensors and the micro electrodes are described. The photo sensors may receive incoming light. The circuit may drive the micro electrodes to stimulate neuron cells for enabling perception of a vision of the light captured by the photo sensors. The guard rings may confine electric flows from the micro electrodes to the targeted neuron cells. The apparatus may be implemented in a flexible material to conform to a shape of a human eyeball to allow the micro electrodes aligned with the neuron cells for the stimulation.

Abstract: An implant apparatus comprising a plurality of photo sensors, a plurality of micro electrodes, a plurality of guard rings surrounding the micro electrodes and circuitry coupled to the photo sensors and the micro electrodes are described. The photo sensors may receive incoming light. The circuit may drive the micro electrodes to stimulate neuron cells for enabling perception of a vision of the light captured by the photo sensors. The guard rings may confine electric flows from the micro electrodes to the targeted neuron cells. The apparatus may be implemented in a flexible material to conform to a shape of a human eyeball to allow the micro electrodes aligned with the neuron cells for the stimulation.

Abstract: Methods and apparatuses to detect configuration commands from waveforms received at a retina prosthesis device for calibrating the device are described. The device can comprise an array of pixel units to receive light to stimulate neuron cells to cause an effect of visual sensation from the light. The pixel units may have configurable parameters for the stimulation to the neuron cells. The configurable parameters may be updated according to the configuration commands detected without requiring micro processor and non-volatile memory in the device. The stimulation may be generated according to the updated configurable parameters to improve the effect of visual sensation from the light including compensation for the physiological and environmental variations and drifts.

Abstract: Methods and apparatuses for assembly of a non-planar device based on curved chips are described. Slots may be created as longitudinal openings in the chips to reduce bending stresses to increase allowable degrees of deformation of the chips. The chips may be deformed to a desired deformation within the allowable degrees of deformation via the slots. Holding constraints may be provided on at least a portion of the chips to allow the chips to remain curved according the desired deformation.

Abstract: A non-planner integrated circuit device comprising a flexible structure and at least one fixture structure bonded to the flexible structure is described. The flexible structure may be curved in a desired deformation. A plurality of contact areas may be included in the flexible structure. Circuitry may be embedded within the flexible structure to perform processing operations. In one embodiment, the fixture structure may be bonded with the fixture structure via the contact areas to provide holding constraints allowing the flexible structure to remain curved. The bonding pads can also be used to connect communications in electrical signals.

Abstract: An implant apparatus comprising a plurality of photo sensors, a plurality of micro electrodes and circuitry coupled to the photo sensors and the micro electrodes are described. The photo sensors may receive incoming light. The circuit may drive the micro electrodes to stimulate neuron cells for enabling perception of a vision of the light captured by the photo sensors. The apparatus may be implemented in a flexible material to conform to a shape of a human eyeball to allow the micro electrodes aligned with the neuron cells for the stimulation.

Abstract: Methods and apparatuses for configuring an implantable device to interface with retina cells are described. The device may comprise an array of pixel units capable of stimulating the retina cells are described. The pixel units may operate in a mode of operation selected from a plurality of modes including a normal mode and a calibration mode. A control circuitry of the device may be configured to switch the mode of operation for the pixel units. In one embodiment, the pixel units may be configured to receive light for stimulating the retina cells during the normal mode to enable perception of the light. During the calibration mode, the pixel units may be configured to adjust amount of stimulation to the retina cells.

Abstract: Methods and apparatuses for assembly of a non-planar device based on curved chips are described. Slots may be created as longitudinal openings in the chips to reduce bending stresses to increase allowable degrees of deformation of the chips. The chips may be deformed to a desired deformation within the allowable degrees of deformation via the slots. Holding constraints may be provided on at least a portion of the chips to allow the chips to remain curved according the desired deformation.