Abstract: The present invention provides a pharmaceutical composition of diltiazem hydrochloride. The pharmaceutical composition is preferably a gel and comprises diltiazem hydrochloride and excipients including propylene glycol, benzoic acid, and a gel matrix, which comprises one or both of povidone and hydroxypropyl cellulose. Based on percentage by weight, the diltiazem hydrochloride accounts for 1%-5%, the gel matrix accounts for 5%-10%, with pH maintained at 3.0-4.5. A preparation method is provided accordingly, with simple and readily available raw materials and stable quality.

Abstract: The present invention provides a pharmaceutical composition of diltiazem hydrochloride. The pharmaceutical composition is preferably a gel and consists of diltiazem hydrochloride and excipients including propylene glycol, benzoic acid, and a gel matrix, which is one of or a mixture of povidone and hydroxypropyl cellulose. Based on percentage by weight, the diltiazem hydrochloride accounts for 1%-5%, the benzoic acid accounts for 0.1%-5.0%, the gel matrix accounts for 5%-10%, and the balance is propylene glycol, with pH maintained at 3.0-4.5. A preparation method is provided accordingly, with simple and readily available raw materials and stable quality.

Abstract: The present invention provides a pharmaceutical composition of diltiazem hydrochloride. The pharmaceutical composition is preferably a gel and consists of diltiazem hydrochloride and excipients including propylene glycol, benzoic acid, and a gel matrix, which is one of or a mixture of povidone and hydroxypropyl cellulose. Based on percentage by weight, the diltiazem hydrochloride accounts for 1%-5%, the benzoic acid accounts for 0.1%-5.0%, the gel matrix accounts for 5%-10%, and the balance is propylene glycol, with pH maintained at 3.0-4.5. A preparation method is provided accordingly, with simple and readily available raw materials and stable quality.

Abstract: Disclosed herein is a fast-dispersing suspending composition which promotes the formation of a suspension for pharmaceutical, food and veterinary products. The composition includes a suspending agent, a diluent, and a glidant, wherein the amounts of these agents are selected to enable the dispersion of the composition and the formation of the suspension. Also disclosed are a method of forming a suspension of a solid dosage form and a method of administering the resulting suspension to a subject.

Abstract: Disclosed herein is a fast-dispersing suspending composition which promotes the formation of a suspension for pharmaceutical, food and veterinary products. The composition includes a suspending agent, a diluent, and a glidant, wherein the amounts of these agents are selected to enable the dispersion of the composition and the formation of the suspension. Also disclosed are a method of forming a suspension of a solid dosage form and a method of administering the resulting suspension to a subject.