Abstract: Catheter-based systems are disclosed for geometrically and temporally controlled deliveries of fluid agents to the heart. Each system includes an elongate catheter shaft, a tissue penetration element at the shaft distal end, and a handle at the shaft proximal end for manipulating the penetrating element. The penetrating element and a proximate conductive coil provide bipolar sensing electrodes. One version of the system includes a fluid lumen through the penetrating element and a contrast fluid lumen open at the catheter shaft distal end. In other versions, the penetrating element contains two fluid lumens. These systems facilitate tissue mapping and therapeutic agent delivery protocols in which several agents can be simultaneously delivered at a depth within heart tissue, prevented from intermingling until they reach the tissue. Treatment and contrast agents can be delivered simultaneously or temporally spaced, directed to the same region or to different regions separated by intervening tissue.

Abstract: An apparatus, system, method, and program for facilitating the design of electronic assemblies include transmitting a user interface application to a user over a publicly-accessible global network. The user interface application is updated in response to electronic assembly design data entered by the user.

Abstract: An apparatus, system, method, and program for facilitating the design of a bare board circuit board include transmitting a user interface application to a user over a publicly-accessible global network. The user interface application is updated in response to circuit board design data entered by the user.

Abstract: Catheter-based systems are disclosed for geometrically and temporally controlled deliveries of fluid agents to the heart. Each system includes an elongate catheter shaft, a helical, linear or curved tissue penetration element at the distal end of the shaft, and a handle at the proximal end of the shaft for manipulating the penetrating element through the catheter shaft. The penetrating element and a conductive coil near the shaft distal end provide a pair of electrodes for bipolar sensing of tissue electrical activity. One version of the system includes a fluid lumen through the penetrating element and a contrast fluid lumen open at the catheter shaft distal end. In other versions of the catheter system, the penetrating element contains two fluid lumens. These systems facilitate a variety of tissue mapping and therapeutic agent delivery protocols in which several agents can be simultaneously delivered at a depth within heart tissue, prevented from intermingling until they reach the tissue.

Abstract: An apparatus, system, method, and program for facilitating the design of a bare board circuit board include transmitting a user interface application to a user over a publicly-accessible global network. The user interface application is updated in response to circuit board design data entered by the user.