Patents by Inventor Loren RUSSELL
Loren RUSSELL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240077516Abstract: Exemplary embodiments of the present disclosure can include, for example, an atomic force microscopy (AFM) system, including a cantilever(s), an optical pickup unit(s) (OPU(s)) including a laser positioned over the cantilever(s), and a power source providing noise with a noise level that is below 300 Picometers. The noise level of the power source can be below 200 Picometers. A digitizing arrangement can be included which can be associated with the OPU. The digitizing arrangement(s) can have a bandwidth of about 2 MHZ. The OPU(s) can have a detection bandwidth of at least 80 MHZ. The exemplary apparatus can be combined with a chemical protocol and statistical signal processing and image analysis procedures to map DNA at high speed and accuracy.Type: ApplicationFiled: August 8, 2023Publication date: March 7, 2024Inventors: Jason REED, Andrey MIKHEYKIN, Loren PICCO, Oliver PAYTON, Freddie RUSSELL-PAVIER
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Publication number: 20230348834Abstract: A packed-bed bioreactor is provided that includes: a vessel having an interior cavity defined by an outer wall; and a center column disposed within the interior cavity. The center column includes a columnar sidewall defining an inner region within the center column, the columnar sidewall separating the inner region from an outer region within the interior cavity. The bioreactor further includes a cell culture substrate disposed in the outer region of the cavity, the cell culture substrate surrounding the center column; at least one port extending through the vessel for at least one supply and removal of media to or from the interior cavity; and a fountain head element disposed above the center column.Type: ApplicationFiled: October 30, 2020Publication date: November 2, 2023Inventors: Sumitava De, Abhijit Rao, Ryann Loren Russell, Yujian Sun
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Publication number: 20230272326Abstract: Devices and systems for product transfer, such as a dissolvable microcarriers, are described. In one example, the product delivery device may include an inlet port; a conical section that may include a wide end and a narrow end; an outlet port flush with the narrow end of the conical section and extending away from the conical section; and a securement feature configured to connect the wide end of the conical section to a container. In another example, a system for aseptic dry product delivery may include a container at least partially filled with the aseptic dry product; a product delivery device; a pressure source connected to an inlet port; and a receiving vessel where the aseptic dry product is collected.Type: ApplicationFiled: May 4, 2023Publication date: August 31, 2023Inventors: Ryann Loren Russell, Paul Kevin Seeto
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Patent number: 11655440Abstract: Devices and systems for product transfer, such as a dissolvable microcarriers, are described. In one example, the product delivery device may include an inlet port; a conical section that may include a wide end and a narrow end; an outlet port flush with the narrow end of the conical section and extending away from the conical section; and a securement feature configured to connect the wide end of the conical section to a container. In another example, a system for aseptic dry product delivery may include a container at least partially filled with the aseptic dry product; a product delivery device; a pressure source connected to an inlet port; and a receiving vessel where the aseptic dry product is collected.Type: GrantFiled: November 26, 2018Date of Patent: May 23, 2023Assignee: CORNING INCORPORATEDInventors: Ryann Loren Russell, Paul Kevin Seeto
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Publication number: 20220411737Abstract: An aseptic bioprocess package is provided herein. The aseptic bioprocess package includes a 2D flexible container including an interior compartment, a height having an upper half and a lower half, an inlet and an outlet, the inlet and the outlet being disposed on the same half of the 2D flexible container and a channel-forming feature in the interior compartment of the container, the channel-forming feature being configured to maintain a fluid flow path that fluidly connects the interior compartment of the flexible container with the outlet.Type: ApplicationFiled: September 1, 2022Publication date: December 29, 2022Inventors: Vasiliy Nikolaevich Goral, Ryann Loren Russell, JR.
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Publication number: 20220235320Abstract: A cell culture article is provided. The cell culture article includes a substrate of a polygalacturonic acid compound crosslinked with a divalent cation, the polygalacturonic acid compound being selected from at least one of: pectic acid; partially esterified pectic acid, partially amidated pectic acid and salts thereof. The substrate is digestible by digestion reagents into components including of galacturonic acid monomers and the divalent cation. Methods of harvesting cells from the cell culture article are also provided. The methods include performing a series of wash and/or centrifugation cycles to reduce components in the harvest solution.Type: ApplicationFiled: June 2, 2020Publication date: July 28, 2022Inventors: Martial Hervy, Liepin Huang, Jinlin Peng, Ryann Loren Russell, Jeffery Joseph Scibek, Yue Zhou
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Publication number: 20210252466Abstract: A removable baffle insert can be used in connection with containers such as bioreactors. The baffle insert can include a plurality of elongated baffle members configured to fit in a tube and contact the interior wall of the tube. The baffle insert can also include interconnection members coupled to the plurality of elongated baffle members. The interconnection members hold the plurality of baffle members together in a spaced apart relationship. In some embodiments, the baffle insert has a cross-sectional geometry that is larger than a cross-sectional geometry of the tube and the interconnection member is configured to bias the plurality of baffle members against the interior wall of the tube.Type: ApplicationFiled: June 4, 2019Publication date: August 19, 2021Inventor: Ryann Loren Russell
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Publication number: 20200360838Abstract: A method for separating at least one target compound from a feed solution is provided. The method includes filling a bioprocess package with a chromatography resin. The bioprocess package includes a 2D flexible container comprising an interior compartment, a height having an upper half and a lower half, an inlet and an outlet, the inlet and the outlet being disposed on the same half of the 2D flexible container, the channel-forming feature being configured to maintain a fluid flow path that fluidly connects the interior compartment of the flexible container with the outlet. The method further includes flowing a feed solution into the bioprocess package to contact the chromatography resin such that substantially all of the at least one target compound binds to the chromatography resin, washing the chromatography resin in the bioprocess package, and eluting the chromatography resin.Type: ApplicationFiled: November 30, 2018Publication date: November 19, 2020Inventors: Vasiliy Nikolaevich Goral, Ryann Loren Russell
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Publication number: 20200354665Abstract: Devices and systems for product transfer, such as a dissolvable microcarriers, are described. In one example, the product delivery device may include an inlet port; a conical section that may include a wide end and a narrow end; an outlet port flush with the narrow end of the conical section and extending away from the conical section; and a securement feature configured to connect the wide end of the conical section to a container. In another example, a system for aseptic dry product delivery may include a container at least partially filled with the aseptic dry product; a product delivery device; a pressure source connected to an inlet port; and a receiving vessel where the aseptic dry product is collected.Type: ApplicationFiled: November 26, 2018Publication date: November 12, 2020Inventors: Ryann Loren Russell, Paul Kevin Seeto
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Publication number: 20200332242Abstract: A perfusion bioreactor system is provided herein. The perfusion bioreactor system includes a vessel having a wall at least partially defining an interior compartment for receiving fluid, at least one port fluidly connected to at least one of a plurality of external sources and at least one outlet fluidly connected to a small pore membrane device.Type: ApplicationFiled: November 20, 2018Publication date: October 22, 2020Inventor: Ryann Loren Russell
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Patent number: 10704571Abstract: A poppet valve system that includes a valve body having a first and second end and defining a valve cavity and a poppet assembly extending from the first end to the second end and through the valve cavity. The poppet assembly can include a movable poppet head disposed at the first end of the poppet assembly and configured generate a seal by contacting a portion of the valve body and configured to define an opening between the valve cavity and a pressure cavity. The poppet assembly can also include a movable guiding element disposed at the second end of the valve body and a shaft extending from the first end to the second end and coupled to the poppet head and guiding element.Type: GrantFiled: June 4, 2018Date of Patent: July 7, 2020Assignee: OTHER LAB, LLCInventors: Pete Lynn, Kevin Albert, Giancarlo Nucci, Tim Swift, Maria Telleria, Loren Russell, Jonathan Pompa
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Publication number: 20200115666Abstract: An aseptic bioprocess package is provided herein. The aseptic bioprocess package includes a 2D flexible container including an interior compartment, a height having an upper half and a lower half, an inlet and an outlet, the inlet and the outlet being disposed on the same half of the 2D flexible container and a channel-forming feature in the interior compartment of the container, the channel-forming feature being configured to maintain a fluid flow path that fluidly connects the interior compartment of the flexible container with the outlet.Type: ApplicationFiled: March 16, 2018Publication date: April 16, 2020Inventors: Vasiliy Nikolaevich Goral, Ryann Loren Russell, JR.
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Patent number: 10279994Abstract: Waste receptacles and retractable casters for such waste receptacles are provided. The waste receptacle includes a housing that has an inner volume accessible by an opening. The housing also includes a base. The waste receptacle includes at least one foot attached to the base that is configured to support the waste receptacle in a standing position. On the housing is at least one retractable caster assembly with a caster moveable between a retracted position and an extended position in which the caster extends past the at least one foot to engage a surface on which the waste receptacle is placed. The waste receptacle is selectively disposed in either a standing position or a mobile position in which the receptacle is moveable along the surface by the retractable caster assembly.Type: GrantFiled: August 27, 2018Date of Patent: May 7, 2019Assignee: Rubbermaid Commercial Products LLCInventors: Christopher Loren Russell, Adam Luedke, Jacob Wayne Connelly, Gary DeCarr
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Publication number: 20190062049Abstract: Waste receptacles and retractable casters for such waste receptacles are provided. The waste receptacle includes a housing that has an inner volume accessible by an opening. The housing also includes a base. The waste receptacle includes at least one foot attached to the base that is configured to support the waste receptacle in a standing position. On the housing is at least one retractable caster assembly with a caster moveable between a retracted position and an extended position in which the caster extends past the at least one foot to engage a surface on which the waste receptacle is placed. The waste receptacle is selectively disposed in either a standing position or a mobile position in which the receptacle is moveable along the surface by the retractable caster assembly.Type: ApplicationFiled: August 27, 2018Publication date: February 28, 2019Inventors: Christopher Loren Russell, Adam Luedke, Jacob Wayne Connelly, Gary DeCarr
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Publication number: 20180283414Abstract: A poppet valve system that includes a valve body having a first and second end and defining a valve cavity and a poppet assembly extending from the first end to the second end and through the valve cavity. The poppet assembly can include a movable poppet head disposed at the first end of the poppet assembly and configured generate a seal by contacting a portion of the valve body and configured to define an opening between the valve cavity and a pressure cavity. The poppet assembly can also include a movable guiding element disposed at the second end of the valve body and a shaft extending from the first end to the second end and coupled to the poppet head and guiding element.Type: ApplicationFiled: June 4, 2018Publication date: October 4, 2018Inventors: Pete LYNN, Kevin ALBERT, Giancarlo NUCCI, Tim SWIFT, Maria TELLERIA, Loren RUSSELL, Jonathan POMPA
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Patent number: 9995321Abstract: A poppet valve system that includes a valve body having a first and second end and defining a valve cavity and a poppet assembly extending from the first end to the second end and through the valve cavity. The poppet assembly can include a movable poppet head disposed at the first end of the poppet assembly and configured generate a seal by contacting a portion of the valve body and configured to define an opening between the valve cavity and a pressure cavity. The poppet assembly can also include a movable guiding element disposed at the second end of the valve body and a shaft extending from the first end to the second end and coupled to the poppet head and guiding element.Type: GrantFiled: March 28, 2016Date of Patent: June 12, 2018Assignee: OTHER LAB, LLCInventors: Pete Lynn, Kevin Albert, Giancarlo Nucci, Tim Swift, Maria Telleria, Loren Russell, Jonathan Pompa
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Publication number: 20160281748Abstract: A poppet valve system that includes a valve body having a first and second end and defining a valve cavity and a poppet assembly extending from the first end to the second end and through the valve cavity. The poppet assembly can include a movable poppet head disposed at the first end of the poppet assembly and configured generate a seal by contacting a portion of the valve body and configured to define an opening between the valve cavity and a pressure cavity. The poppet assembly can also include a movable guiding element disposed at the second end of the valve body and a shaft extending from the first end to the second end and coupled to the poppet head and guiding element.Type: ApplicationFiled: March 28, 2016Publication date: September 29, 2016Inventors: Pete LYNN, Kevin ALBERT, Giancarlo NUCCI, Tim SWIFT, Maria TELLERIA, Loren RUSSELL, Jonathan POMPA