Patents by Inventor Loren Walensky

Loren Walensky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Selective Mcl-1 binding peptides
    Patent number: 11142554
    Abstract: Provided herein are stabilized peptides that bind Mcl-1. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
    Type: Grant
    Filed: March 18, 2016
    Date of Patent: October 12, 2021
    Assignees: MASSACHUSETTS INSTITUTE OF TECHNOLOGY, Dana-Farber Cancer Institute, Inc.
    Inventors: Raheleh Rezaei-Araghi, Amy Keating, Gregory H. Bird, Loren Walensky
  • SELECTIVE MCL-1 BINDING PEPTIDES
    Publication number: 20180201658
    Abstract: Provided herein are stabilized peptides that bind Mcl-1. Also provided are compositions containing these polypeptides and methods of using such peptides in the treatment of cancer that include administering to a subject one of the polypeptides.
    Type: Application
    Filed: March 18, 2016
    Publication date: July 19, 2018
    Inventors: Raheleh Rezaei-Araghi, Amy Keating, Gregory H. Bird, Loren Walensky
  • Stabilized alpha helical peptides and uses thereof
    Publication number: 20050250680
    Abstract: Novel polypeptides and methods of making and using the same are described herein. The polypeptides include cross-linking (“hydrocarbon stapling”) moieties to provide a tether between two amino acid moieties, which constrains the secondary structure of the polypeptide. The polypeptides described herein can be used to treat diseases characterized by excessive or inadequate cellular death.
    Type: Application
    Filed: November 5, 2004
    Publication date: November 10, 2005
    Inventors: Loren Walensky, Stanley Korsmeyer, Susan Korsmeyer, Gregory Verdin
  • Sperm receptors
    Patent number: 6159707
    Abstract: The present invention provides a nucleic acid comprising a sequence that encodes a sperm receptor that is related to, but is different from, a receptor of the odorant receptor family. The present invention also provides a method of obtaining a nucleic acid that comprises a sequence that encodes a sperm receptor, as well as a means of using the elements of the invention in a method of contraception, a method of detecting autoimmune infertility, and a method of affecting fertility.
    Type: Grant
    Filed: November 8, 1996
    Date of Patent: December 12, 2000
    Assignee: Johns Hopkins University School of Medicine
    Inventors: Gabriele V. Ronnett, Loren Walensky, Martial Ruat, Solomon H. Snyder